在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

OPN3 Antibody, FITC conjugated

  • 中文名稱:
    OPN3兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA872435LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) OPN3 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    OPN3; ECPN; Opsin-3; Encephalopsin; Panopsin
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Opsin-3 protein (313-402AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    G-protein coupled receptor which selectively activates G proteins via ultraviolet A (UVA) light-mediated activation in the skin. Binds both 11-cis retinal and all-trans retinal. Regulates melanogenesis in melanocytes via inhibition of alpha-MSH-induced MC1R-mediated cAMP signaling, modulation of calcium flux, regulation of CAMK2 phosphorylation, and subsequently phosphorylation of CREB, p38, ERK and MITF in response to blue light. Plays a role in melanocyte survival through regulation of intracellular calcium levels and subsequent BCL2/RAF1 signaling. Additionally regulates apoptosis via cytochrome c release and subsequent activation of the caspase cascade. Required for TYR and DCT blue light-induced complex formation in melanocytes. Involved in keratinocyte differentiation in response to blue-light. Required for the UVA-mediated induction of calcium and mitogen-activated protein kinase signaling resulting in the expression of MMP1, MMP2, MMP3, MMP9 and TIMP1 in dermal fibroblasts. Plays a role in light-mediated glucose uptake, mitochondrial respiration and fatty acid metabolism in brown adipocyte tissues. May be involved in photorelaxation of airway smooth muscle cells, via blue-light dependent GPCR signaling pathways.
  • 基因功能參考文獻:
    1. Decreased OPN3 levels in Bel7402(5-FU) cells activated the anti-apoptotic pathway through increasing phospho-Akt and the Bcl2/Bax ratio, while overexpression of OPN3 inactivated this pathway. PMID: 22313545
    2. Assignment of panopsin (OPN3) to human chromosome band 1q43 PMID: 12063405
    3. Human OPN3 gene consists of six exons and expresses various splice variants. PMID: 12242008
    4. Polymorphisms in the OPN3 and CHML genes are associated with asthma and atopic asthma. PMID: 18344558
    5. Related persons with heterozygous germline deletions of 1q42.3, which includes EXO1, RGS7, KMO, CHML, and OPN3, showed no phenotypic abnormalities other than multiple leiomyomatosis. PMID: 14623461

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cytoplasm.
  • 蛋白家族:
    G-protein coupled receptor 1 family, Opsin subfamily
  • 組織特異性:
    Expressed in tracheal airway smooth muscle (at protein level). Expressed throughout the epidermis and dermis, predominantly in the basal layer on the facial and abdominal skin (at protein level). Expressed in dermal fibroblasts (at protein level). Express
  • 數據庫鏈接:

    HGNC: 14007

    OMIM: 606695

    KEGG: hsa:23596

    STRING: 9606.ENSP00000355512

    UniGene: Hs.409081



主站蜘蛛池模板: 超清制服丝袜无码av福利网| 国产av丝袜一区二区三区| 欧美日韩精品一区二区性色a+v | 97人洗澡从澡人人爽人人模| 精品国产一区二区三区国产区| 国产美女精品视频线播放| 亚洲欧美成aⅴ人在线观看| 欧美激情精品久久| 久久99精品国产.久久久久| 强迫大乳人妻中文字幕| 久久婷婷五月综合色俺也想去 | 亚洲综合熟女久久久40p| 少妇被粗大的猛烈进出动视频| 国产成人精品无码a区在线观看| 欧美xxxx做受性欧美88| 亚洲国产精品成人无码区| 国产欧美另类久久久精品不卡| 亚洲暴爽av人人爽日日碰| 久久躁狠狠躁夜夜av| 免费无码又爽又刺激高潮 | 欧美国产日韩a欧美在线观看| 国产亚洲精品资源在线26u| 久久综合狠狠综合久久综合88| 天天躁日日躁狠狠很躁| 丁香婷婷激情综合俺也去| 国产精品亚洲а∨怡红院| 露脸内射熟女--69xx| 国产xxx69麻豆国语对白| 成 人 在 线 免费观看| 韩国乱码片免费看| 免费无码久久成人网站入口 | 国产精品调教视频一区| a亚洲va欧美va国产综合| 亚洲成在人线av| 99精品国产福利在线观看| 成人做受120秒试看试看视频| 中文无码乱人伦中文视频在线| 男人添女人下部高潮视频| 色综合天天天天综合狠狠爱| 巨乳美乳一区二区三区| 蜜桃视频一区二区在线观看|