在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

OLA1 Antibody

  • 中文名稱:
    OLA1兔多克隆抗體
  • 貨號:
    CSB-PA016318GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    OLA1
  • 別名:
    DKFZp313H1942 antibody; DNA damage-regulated overexpressed in cancer 45 protein antibody; DOC45 antibody; EC 3.6.3 antibody; GBP45 antibody; GTP-binding protein 9 (putative) antibody; GTP-binding protein 9 antibody; GTP-binding protein PTD004 antibody; homologous yeast-44.2 protein antibody; Obg like ATPase 1 antibody; Obg-like ATPase 1 antibody; OLA1 antibody; OLA1_HUMAN antibody; PTD004 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human OLA1
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
  • 基因功能參考文獻:
    1. No germline mutations were found in the OLA1 gene in in patients with BRCA1/2 mutation-negative suspected hereditary breast and ovarian cancer. PMID: 27271530
    2. OLA1 contributes to epithelial-mesenchymal transition by modulating the GSK3beta/Snail/E-cadherin signaling, and its overexpression is associated with clinical progression and poor survival in lung cancer patients. PMID: 26863455
    3. Our work suggests that OLA1 is a novel translational GTPase and plays a suppressive role in translation and cell survival, as well as cancer growth and progression. PMID: 26283179
    4. OLA1 plays an important negative role in cell adhesion and spreading, in part through the regulation of FAK expression and cofilin phosphorylation, and manipulation of OLA1 may lead to significant changes in cell adhesion and the associated phenotypes. PMID: 24486488
    5. OLA1 plays an important role in centrosome regulation together with BRCA1. PMID: 24289923
    6. Downregulation of OLA1 in mammalian cells by either RNAi or targeted gene disruption results in reduced steady-state levels of HSP70, impaired HSP70 induction by heat, and functionally, increased cellular sensitivity to heat shock. PMID: 23412384
    7. DOC45 is a novel ATPase that is linked to cellular stress response and tumorigenesis, and may also serve as a valuable tumor marker. PMID: 20053727
    8. knockdown of OLA1 inhibits breast cancer cell migration and invasion through a mechanism that involves the modulation of intracellular ROS levels PMID: 19882753
    9. Results indicate that Gbp45/OLA1 plays important roles in cell proliferation and death related to mitochondrial function. PMID: 18536999
    10. OLA1 suppresses the antioxidant response through nontranscriptional mechanisms. PMID: 19706404

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Nucleus, nucleolus.
  • 蛋白家族:
    TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family, YchF/OLA1 subfamily
  • 組織特異性:
    Expressed in all tissues tested but its expression is more abundant in testis, liver, lung, and brain. Overexpressed in several malignancies, including cancers of the colon, rectum, ovary, lung, stomach, and uterus.
  • 數據庫鏈接:

    HGNC: 28833

    OMIM: 611175

    KEGG: hsa:29789

    STRING: 9606.ENSP00000284719

    UniGene: Hs.157351



主站蜘蛛池模板: 国产福利萌白酱精品一区| 成人免费无码大片a毛片小说| 亚洲成a人片在线观看的电影| 99久久精品视香蕉蕉| 久久综合九色综合久99| 无码人妻一区二区三区免费看| 久久影院午夜理论片无码| 日韩欧美群交p内射捆绑| 欧美亚洲另类丝袜综合网| 国产成人av大片在线播放| 波多野结衣人妻| 欧洲熟妇色xxxx欧美老妇多毛网站| 亚洲欧洲日韩国内高清| 蜜芽av无码精品国产午夜| 奇米影视7777狠狠狠狠影视| 午夜免费男女aaaa片| 一本一道波多野结衣av一区| 成av人片在线观看www| 欧洲人免费视频网站在线| 在线播放国产麻豆va剧情| 欧美黑人大战白嫩在线| 黑人巨大精品欧美黑寡妇| 国产麻豆成人精品av| 在线日产精品一区| 天堂av色综合久久天堂| 国产成人a区在线观看视频 | 国产97色在线 | 亚洲| а√8天堂中文官网资源| 亚洲美女高清无水av| 亚洲人成黄网站69影院| 精品香蕉一区二区三区| 日韩人妻无码精品免费shipin| 亚洲成国产人片在线观看| 欧美又黄又大又爽a片三年片| 欧洲美熟女乱又伦| 隔壁老王国产在线精品| 精产国品一二三产区9977| 日本 精品 高清不卡| 国产欧美久久一区二区 | 国产揄拍国产精品| 免费国产黄网站在线观看可以下载|