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Your Good Partner in Biology Research

NXN Antibody

  • 中文名稱:
    NXN兔多克隆抗體
  • 貨號:
    CSB-PA016224GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    NXN
  • 別名:
    FLJ12614 antibody; NRX antibody; nucleoredoxin 1 antibody; Nucleoredoxin antibody; Nxn antibody; NXN_HUMAN antibody; OTTHUMP00000115356 antibody; TRG 4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human NXN
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).
  • 基因功能參考文獻:
    1. identified nucleoredoxin as an interaction partner of Sec63; characterized this interaction; Sec63 is linked to the Wnt signaling pathways and this interaction may be the reason why mutations in SEC63 can lead to polycystic liver disease PMID: 21251912
    2. Nucleoredoxin is a novel thioredoxin family member involved in cell growth and differentiation [review] PMID: 17567240
  • 亞細胞定位:
    Cytoplasm, cytosol. Nucleus.
  • 蛋白家族:
    Nucleoredoxin family
  • 數據庫鏈接:

    HGNC: 18008

    OMIM: 612895

    KEGG: hsa:64359

    STRING: 9606.ENSP00000337443

    UniGene: Hs.527989



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