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NXN Antibody, FITC conjugated

  • 中文名稱(chēng)：
    NXN兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào)：
    CSB-PA016224HC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) NXN Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NXN
  • 別名：
    FLJ12614 antibody; NRX antibody; nucleoredoxin 1 antibody; Nucleoredoxin antibody; Nxn antibody; NXN_HUMAN antibody; OTTHUMP00000115356 antibody; TRG 4 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Nucleoredoxin protein (155-435AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A).
  • 基因功能參考文獻(xiàn)：
    1. identified nucleoredoxin as an interaction partner of Sec63; characterized this interaction; Sec63 is linked to the Wnt signaling pathways and this interaction may be the reason why mutations in SEC63 can lead to polycystic liver disease PMID: 21251912
    2. Nucleoredoxin is a novel thioredoxin family member involved in cell growth and differentiation [review] PMID: 17567240
  • 亞細(xì)胞定位：
    Cytoplasm, cytosol. Nucleus.
  • 蛋白家族：
    Nucleoredoxin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 18008

    OMIM: 612895

    KEGG: hsa:64359

    STRING: 9606.ENSP00000337443

    UniGene: Hs.527989



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