在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NVL Antibody

NVL Antibody

  • 中文名稱(chēng)：
    NVL兔多克隆抗體
  • 貨號(hào)：
    CSB-PA016216GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    NVL
  • 別名：
    Nuclear valosin containing protein like antibody; Nuclear valosin-containing protein-like antibody; Nuclear VCP like antibody; Nuclear VCP-like protein antibody; Nvl antibody; NVL_HUMAN antibody; NVLp antibody; OTTHUMP00000035641 antibody; OTTHUMP00000216593 antibody; OTTHUMP00000216594 antibody; OTTHUMP00000216599 antibody; OTTHUMP00000216600 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human NVL
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Participates in the assembly of the telomerase holoenzyme and effecting of telomerase activity via its interaction with TERT. Involved in both early and late stages of the pre-rRNA processing pathways. Spatiotemporally regulates 60S ribosomal subunit biogenesis in the nucleolus. Catalyzes the release of specific assembly factors, such as WDR74, from pre-60S ribosomal particles through the ATPase activity.
  • 基因功能參考文獻(xiàn)：
    1. knockdown of WDR74 leads to significant defects in the pre-rRNA cleavage within the internal transcribed spacer 1, occurring in an early stage of the processing pathway. When the dissociation of WDR74 from the MTR4-containing exonuclease complex was impaired upon expression of mutant NVL2, the same processing defect, with partial migration of WDR74 from the nucleolus towards the nucleoplasm, was observed. PMID: 29107693
    2. Results indicated that the NVL gene may contain overlapping common genetic risk factors for major depressive disorder and schizophrenia in the Han Chinese population PMID: 25891250
    3. results suggest that WDR74 is a novel regulatory protein of the MTR4-exsosome complex whose interaction is regulated by NVL2 and is involved in ribosome biogenesis PMID: 26456651
    4. suggest that NVL2 is involved in pre-rRNA processing by associating with the nuclear exosome complex and that MPP6 is required for maintaining the integrity of this rRNA processing complex PMID: 26166824
    5. these findings suggest that NVL2 is essential for telomerase biogenesis and provides an alternative approach for inhibiting telomerase activity in cancer. PMID: 22226966
    6. interaction of NVL2 with ribosomal protein L5 is ATP-dependent and likely contributes to the nucleolar translocation of NVL2 PMID: 15469983
    7. Nuclear VCP/p97-like protein 2 might regulate the association/dissociation reaction of DOB1 with pre-ribosomal particles by acting as a molecular chaperone. PMID: 16782053

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    [Isoform 2]: Nucleus, nucleoplasm.; [Isoform 1]: Nucleus, nucleolus. Nucleus, nucleoplasm.
  • 蛋白家族：
    AAA ATPase family
  • 組織特異性：
    Widely expressed. Highest level of expression in heart, placenta, skeletal muscle, pancreas and retina.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 8070

    OMIM: 602426

    KEGG: hsa:4931

    STRING: 9606.ENSP00000281701

    UniGene: Hs.497867



主站蜘蛛池模板： 丰满少妇被猛烈进av毛片| 天干天干夜啦天干天干国产| 2021年精品国产福利在线| 国产精品白浆无码流出视频| 熟女内射v888av| 中文字幕无码免费不卡视频| 日产欧美国产日韩精品| 人妻熟女一区二区aⅴ清水理纱| 国产亚洲视频中文字幕97精品| 色欲色香天天天综合vvv| 久久久国产打桩机| 国产亚洲精品久久久久久打不开 | 久久久橹橹橹久久久久| 久久久久成人精品| 国产精品多人p群无码| 国产美女精品自在线拍免费| 英语老师丝袜娇喘好爽视频| 五月丁香啪啪| 色欲aⅴ亚洲情无码av蜜桃| 国产办公室无码视频在线观看| 成人无码a∨电影免费| 人人入人人爱| 欧美老人巨大xxxx做受视频| 成人区精品一区二区不卡| 亚洲aⅴ在线无码播放毛片一线天| 国产色秀视频在线播放| 日日噜噜噜夜夜爽爽狠狠| 午夜影视啪啪免费体验区入口 | 一区二区三区四区在线 | 中国| 国产精品毛片更新无码| 久久久久国产a免费观看rela| 日韩乱码人妻无码中文字幕视频| 国产偷窥盗摄一区二区| 亚洲日韩中文字幕在线播放| 欧美性插b在线视频网站| 看成年全黄大色黄大片| 日韩不卡1卡2卡三卡网站| 久久综合伊人77777麻豆| 欧美日韩不卡视频合集| 免费精品国偷自产在线2020| 夜夜春夜夜爽|