在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NUSAP1 Antibody

  • 中文名稱:
    NUSAP1兔多克隆抗體
  • 貨號:
    CSB-PA222749
  • 規格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HT-29 cells, using NUSAP1 antibody.
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) NUSAP1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    NUSAP1
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human NUSAP1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Microtubule-associated protein with the capacity to bundle and stabilize microtubules. May associate with chromosomes and promote the organization of mitotic spindle microtubules around them.
  • 基因功能參考文獻:
    1. Study suggests that NUSAP1 might be involved in glioma progression and can serve as a prognosis biomarker for glioma patients. NUSAP1 silencing suppresses malignant phenotypes of glioma cells, which offer a theoretical foundation for further investigation of NUSAP1 as a possible target with advantages for glioma treatment. PMID: 29336114
    2. NUSAP1 is overexpressed in colon cancer and high expression of NUSAP1 acts as an independent predictive factor for poor prognosis in colon cancer PMID: 29853313
    3. Findings indicated that NUSAP1 played an important role in promoting aggressiveness in astrocytoma via activating the HH pathway. PMID: 28899410
    4. our work provides a better understanding of the function of NUSAP1 in aggressive prostate cancers, provides rationale for using NUSAP1 as a prognostic biomarker, and sets the stage for developing improved therapeutic strategies for prostate and other cancers. PMID: 28404898
    5. NUSAP1 contributes to accurate chromosome segregation by acting as a co-factor for RanBP2-RanGAP1-UBC9 during cell division. PMID: 28900032
    6. NuSAP governs chromosome oscillation via regulation of Kid, facilitating the Kid-generated polar ejection force. Depletion of NuSAP significantly suppresses the amplitude and velocity of chromosome oscillation. PMID: 26839278
    7. NUSAP1 may be a crucial biomarker for oral squamous cell carcinoma. down-regulated NUSAP1 expression suppresses tumor proliferation and also enhances anti-tumor effect of paclitaxel by activating apoptotic pathways. PMID: 26554377
    8. High levels of NuSAP1 expression were related to poor disease-free survival, particularly in triple-negative breast cancer. PMID: 26485712
    9. A novel association between BRCA1 and NUSAP1 is revealed and a mechanism whereby NUSAP1 is involved in carcinogenesis was elusidated. PMID: 24521615
    10. High NUSAP1 expression is associated with cervical cancer. PMID: 23405241
    11. NuSAP is a novel biomarker for prostate cancer recurrence after surgery and its overexpression appears to be driven in part by E2F1 activation PMID: 22349817
    12. Phosphorylation of NuSAP by Cdk1 is an important mechanism to regulate microtubule dynamics during cell cycle progression. PMID: 22101338
    13. Interphase NuSAP-chromatin interaction suggests additional functions for NuSAP, as recently identified for other nuclear spindle assembly factors with a role in gene expression or DNA damage response. PMID: 21782797
    14. NuSAP1 is recognized as an immunogenic antigen in 65% of patients with AML following allogeneic HCT and suggests a tumor antigen role. PMID: 20053754

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus, nucleolus. Cytoplasm, cytoskeleton, spindle. Chromosome.
  • 蛋白家族:
    NUSAP family
  • 數據庫鏈接:

    HGNC: 18538

    OMIM: 612818

    KEGG: hsa:51203

    STRING: 9606.ENSP00000453403

    UniGene: Hs.615092



主站蜘蛛池模板: 免费人成网站视频在线观看国内| 国产综合色在线视频区| 高清国产一区二区三区在线| 国产极品久久久久久久久| 97久久草草超级碰碰碰| 少妇扒开粉嫩小泬视频| 狠狠色噜噜狠狠色综合久| 少妇被粗大的猛进出69影院| 加勒比东京热无码一区| 國产一二三内射在线看片| 欧美牲交a欧美牲交aⅴ另类| 国产成人精品一区二区不卡| 日本污ww视频网站| 亚洲国产婷婷六月丁香| 3344永久在线观看视频| 日本亚州视频在线八a| 8888四色奇米在线观看| 久久久久久国产精品无码超碰| 亚洲精品国产精品国产自2022| 337p日本欧洲亚洲大胆人人| www一区二区www免费| 亚洲日韩欧美一区二区三区在线| 无码中文字幕免费一区二区三区 | 久久久精品2019免费观看 | 久久九九久精品国产免费直播| 少妇粉嫩小泬喷水视频| 成人无码潮喷在线观看| 国产精品亚洲第一区在线观看| 精品国产aⅴ无码一区二区 | 女人被爽到高潮视频免费国产| 区二区欧美性插b在线视频网站| 五十路熟妇亲子交尾| 久久综合久久爱久久综合伊人| 国产精品久久久久aaaa| 精品国产一区av天美传媒| 亚洲精品av一二三区无码 | 欧美激情a∨在线视频播放| 精品无码人妻一区二区三区品| 欧美精品a∨在线观看| 色综合久久一区二区三区| 激情综合色综合久久综合|