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NUP93 Antibody

  • 中文名稱:
    NUP93兔多克隆抗體
  • 貨號:
    CSB-PA016208GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    NUP93
  • 別名:
    NUP93 antibody; KIAA0095Nuclear pore complex protein Nup93 antibody; 93 kDa nucleoporin antibody; Nucleoporin Nup93 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human NUP93
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
  • 基因功能參考文獻:
    1. we show that knockdown of Nup188 or its binding partner Nup93 leads to a loss of cilia during embryonic development while leaving NPC function largely intact. Many data, including the localization of endogenous Nup188/93 at cilia bases, support their direct role at cilia. Super-resolution imaging of Nup188 shows two barrel-like structures PMID: 27593162
    2. NUP93 and exportin 5 interact with the signaling protein SMAD4 and that NUP93 mutations abrogated interaction with SMAD4 PMID: 26878725
    3. Caspases target only Nup93 and Nup96 within the core structure of the nuclear pore complex PMID: 16286466
  • 相關疾病:
    Nephrotic syndrome 12 (NPHS12)
  • 亞細胞定位:
    Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Nucleus envelope.
  • 蛋白家族:
    Nucleoporin interacting component (NIC) family
  • 數據庫鏈接:

    HGNC: 28958

    OMIM: 614351

    KEGG: hsa:9688

    STRING: 9606.ENSP00000310668

    UniGene: Hs.276878



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