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  4. NUP93 Antibody, FITC conjugated

NUP93 Antibody, FITC conjugated

  • 中文名稱：
    NUP93兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA822683LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NUP93 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NUP93
  • 別名：
    NUP93 antibody; KIAA0095Nuclear pore complex protein Nup93 antibody; 93 kDa nucleoporin antibody; Nucleoporin Nup93 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Nuclear pore complex protein Nup93 protein (14-180AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. During renal development, regulates podocyte migration and proliferation through SMAD4 signaling.
  • 基因功能參考文獻：
    1. we show that knockdown of Nup188 or its binding partner Nup93 leads to a loss of cilia during embryonic development while leaving NPC function largely intact. Many data, including the localization of endogenous Nup188/93 at cilia bases, support their direct role at cilia. Super-resolution imaging of Nup188 shows two barrel-like structures PMID: 27593162
    2. NUP93 and exportin 5 interact with the signaling protein SMAD4 and that NUP93 mutations abrogated interaction with SMAD4 PMID: 26878725
    3. Caspases target only Nup93 and Nup96 within the core structure of the nuclear pore complex PMID: 16286466
  • 相關疾病：
    Nephrotic syndrome 12 (NPHS12)
  • 亞細胞定位：
    Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Nucleus envelope.
  • 蛋白家族：
    Nucleoporin interacting component (NIC) family
  • 數據庫鏈接：

    HGNC: 28958

    OMIM: 614351

    KEGG: hsa:9688

    STRING: 9606.ENSP00000310668

    UniGene: Hs.276878



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