在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NUMBL Antibody, Biotin conjugated

NUMBL Antibody, Biotin conjugated

  • 中文名稱：
    NUMBL兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA897595LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NUMBL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CAG 3A antibody; CAG3A antibody; CTG 3a antibody; CTG3a antibody; NBL antibody; NUMB Drosophilia Homolog Like antibody; Numb homolog (Drosophila) like antibody; Numb homolog like antibody; Numb like protein antibody; NUMB R antibody; Numb-like protein antibody; Numb-R antibody; Numb-related gene antibody; Numb-related protein antibody; NUMBL antibody; NUMBL_HUMAN antibody; NUMBLIKE antibody; NUMBR antibody; TNRC 23 antibody; TNRC23 antibody; Trinucleotide repeat-containing gene 23 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Numb-like protein (447-576AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
  • 基因功能參考文獻：
    1. NumbL can act as an independent tumor suppressor inhibiting the Notch pathway and regulating the cancer stem cell pool PMID: 27613838
    2. let-7c inhibits Notch and progression markers but up-regulates Numbl in pancreatic cancer treated with quercetin PMID: 27521217
    3. Numbl might be involved in the inhibition of growth, proliferation, and invasion of 95-D lung cancer cells. PMID: 23681800
    4. Numbl-Klf4 signaling is critical to maintain multiple nodes of metastatic progression, including persistence of cancer-initiating cells. PMID: 23440423
    5. data suggest that Numbl regulates glioma cell migration and invasion by abrogating TRAF5-induced activation of NF-KappaB PMID: 22593207
    6. NUMBL interacts with TRAF6 and promotes the degradation of TRAF6 in vivo, leading to the inhibition of NF-kappaB signaling pathway. PMID: 20079715
    7. Both gene sequence alterations and amplifications of LNX1 and Numbl are present in a subset of human gliomas. PMID: 18940473

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 數據庫鏈接：

    HGNC: 8061

    OMIM: 604018

    KEGG: hsa:9253

    STRING: 9606.ENSP00000252891

    UniGene: Hs.326953



主站蜘蛛池模板： 成人综合婷婷国产精品久久 | 国产成人综合亚洲看片| 久久久精品94久久精品| 亚洲欧美色中文字幕在线| 麻花传媒在线mv免费观看视频| 成人精品视频一区二区三区尤物| 丰满岳乱妇在线观看中字| 国产情侣真实54分钟在线| 欧美人与禽z0zo牲伦交| 又黄又爽的60分钟视频| 窝窝午夜色视频国产精品破| 又粗又大又硬又长又爽| 四虎成人精品无码永久在线| 蜜臀性色av免费| 久久精品免费一区二区三区| 夜夜高潮夜夜爽夜夜爱爱一区| 国产成人精品一区二区三区视频| 久久久欧美国产精品人妻噜噜| 久久久久免费看成人影片| 色香阁综合无码国产在线| 中文在线www天堂网| 亚洲一卡二卡三卡四卡| 在线人人车操人人看视频| 国产a线视频播放| 亚洲一卡2卡3卡4卡精品 | 成人av一本不卡二卡| 毛片内射久久久一区| 97精品久久久久中文字幕| 中文字幕一二三区波多野结衣| 亚洲v国产v天堂a无码二区| 亚洲日韩中文字幕在线播放 | 欧美午夜成人片在线观看| 内射国产内射夫妻免费频道| 99久久国语露脸精品国产色| 久久se精品一区二区三区 | 亚洲日韩乱码中文无码蜜桃臀网站| 国产suv精品一区二区69| 高清一区二区三区日本久| 国产又黄又爽又色的免费| 人人超碰人人超级碰国| 精品少妇无码av无码专区 |