在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NPTX2 Antibody

  • 中文名稱:
    NPTX2兔多克隆抗體
  • 貨號:
    CSB-PA016030GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    apexin antibody; NARP antibody; neuronal activity-regulated pentaxin antibody; Neuronal pentraxin 2 antibody; Neuronal pentraxin II antibody; Neuronal pentraxin-2 antibody; NP 2 antibody; NP-II antibody; NP2 antibody; NPII antibody; NPTX2 antibody; NPTX2_HUMAN antibody; pentraxin II, neuronal antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human NPTX2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Likely to play role in the modification of cellular properties that underlie long-term plasticity. Binds to agar matrix in a calcium-dependent manner.
  • 基因功能參考文獻:
    1. Neuronal pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer's disease spectrum. This research may advance the current understanding of Alzheimer's disease etiopathogenesis, while expanding early diagnostic techniques through the use of novel pro-inflammatory biomarkers, such as NPTX2. PMID: 27444967
    2. NPTX2 in human cerebrospinal fluid is reduced in subjects with Alzheimer's disease and shows robust correlations with cognitive performance and hippocampal volume. PMID: 28440221
    3. Decreased NPTX2 expression in rectal adenocarcinomas is associated with improved response to neoadjuvant chemoradiation and improved prognosis. PMID: 27083956
    4. we show that NPTX2 is a marker of poor prognosis for neuroblastoma patients. PMID: 26294210
    5. NPTX2 is overexpressed specifically in ccRCC primary tumors. PMID: 24962026
    6. NPTX2 repressed NF-kappaB activity by inhibiting AKT through a p53-PTEN-dependent pathway, thus explaining the hypermethylation and downregulation of NPTX2 in NF-kappaB-activated high-risk glioblastomas. PMID: 24078801
    7. Promoter methylation of NPTX2 is associated with glioblastoma. PMID: 23624749
    8. Detection of aberrant methylation of NPTX2 in pure pancreatic juice samples could be useful as a molecular marker to discriminate between patients with malignant and benign disease of the pancreas PMID: 23360791
    9. The visual cortex of NARP-deficient transgenic mice is hyperexcitable and unable to express ocular dominance, although many aspects of visual function are unimpaired. PMID: 23889936
    10. This study showed that the NPTX2 protein is down-regulated in human primary pancreatic cancers and in pancreatic cancer cell lines. PMID: 22806544
    11. This study demonistrated that childhood-onset mood disorders and suicide attempt association between HOMER1 rs2290639 and between NPTX2 markers rs705315 and rs1681248. PMID: 22460132
    12. Demonstrate for the first time that NARP mutation significantly enhances apoptotic death as a result of three distinct lethal mitochondrial apoptotic insults including oxidative, Ca(2+), and lipid stress. PMID: 21812817
    13. Data indicate that the aberrantly methylated NPTX2 gene may help to distinguish between chronic pancreatitis and pancreatic cancer with conventional diagnostic tools and could become a valuable diagnostic marker. PMID: 21778928
    14. NPTX2, as a tumor-suppressor, plays an anti-tumor effect on pancreatic cancer and its low expression, due to promoter hypermethylation, may play a role in the tumorigenesis of pancreatic cancer. PMID: 21161403
    15. study tested for the association of four SNPs of NPTX2 & haplotypes consisting of the SNPs with autism, between autistic patients & controls in a Japanese population; no significant difference was observed in allele, genotype or haplotype frequencies PMID: 17408830
    16. pancreatic cancer cytology samples had statistically significant higher levels of NPTX2 methylation compared with benign diseases PMID: 17895837
    17. Neuronal pentraxin II is highly upregulated in Parkinson's disease and a novel component of Lewy bodies. PMID: 17987278
    18. Homoplasmic cybrids harboring the 8993T-->G NARP mutation were also protected from death (75% vs 15% survival at 72 hours) by the supplemented medium and their ATP content was similar to controls PMID: 19667215

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 組織特異性:
    Brain, pancreas, liver, heart and skeletal muscle. Highest levels are seen in the testis.
  • 數據庫鏈接:

    HGNC: 7953

    OMIM: 600750

    KEGG: hsa:4885

    STRING: 9606.ENSP00000265634

    UniGene: Hs.3281



主站蜘蛛池模板: 久久久亚洲欧洲日产国码606| 精品无码国产日韩制服丝袜| 国产精品久久久久久久伊一| 中文字幕精品av乱码在线| 欧美人与性囗牲恔配| 99久久综合精品五月天| 亚洲一区二区三区在线播放无码| 亚洲一区波多野结衣在线| 无码av片在线观看免费| 成人影院yy111111| 国产精品老热丝在线观看| 极品少妇hdxx麻豆hdxx| 日韩欧美亚洲综合久久影院d3| 亚洲成在人网站无码天堂| 亚洲一区二区三区日本久久九| 色一情一乱一伦一区二区三区日本| 婷婷四房综合激情五月在线| 国产成人亚洲精品无码车a| 久久中文骚妇内射| 久久欧美与黑人双交男男| 午夜私人成年影院| 美女扒开腿让男人桶爽app免费看| 亚洲日韩一区精品射精| 蜜臀久久99精品久久久久久| 亚洲熟女综合一区二区三区| 天堂а√在线最新版中文| 大香网伊人久久综合网2018| 国产亚洲精久久久久久无码| 亚洲日韩国产成网在线观看| 在阳台上玩弄人妻的乳球| 99精品国产福利一区二区| 无码丰满少妇2在线观看| 老妇肥熟凸凹丰满刺激| 欧美成aⅴ人高清免费| 四虎成人精品永久网站| 麻豆亚洲一区| 国精产品999一区二区三区有限| 又爆又大又粗又硬又黄的a片| 日韩精品射精管理在线观看| 国产成人无码区免费内射一片色欲 | 无码免费无线观看在线视|