在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NKD1 Antibody

NKD1 Antibody

  • 中文名稱：
    NKD1兔多克隆抗體
  • 貨號：
    CSB-PA853369LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Rat heart tissue
      All lanes: NKD1 antibody at 1.8μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 53 kDa
      Observed band size: 53 kDa
    • Immunofluorescence staining of HepG2 cells with CSB-PA853369LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NKD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    NKD1 antibody; NKD antibody; PP7246 antibody; Protein naked cuticle homolog 1 antibody; Naked-1 antibody; hNkd antibody; hNkd1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Rat
  • 免疫原：
    Recombinant Human Protein naked cuticle homolog 1 protein (269-384AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，NKD1 Antibody (CSB-PA853369LA01HU)，的標記方式是Non-conjugated。對于NKD1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA853369LB01HU NKD1 Antibody, HRP conjugated ELISA
    FITC CSB-PA853369LC01HU NKD1 Antibody, FITC conjugated
    Biotin CSB-PA853369LD01HU NKD1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
  • 基因功能參考文獻：
    1. the downregulation of NKD1 may be involved in the proliferation and migration of osteosarcoma cells through the activation of the canonical Wnt signaling pathway. PMID: 29115501
    2. The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocellular carcinoma cells. PMID: 27231134
    3. HNF1A-AS1 promoted HCC cell proliferation by repressing the NKD1 and p21 expression. PMID: 28292020
    4. Data indicate that microRNA miR-744 activated Wnt/beta-catenin pathway by targeting multiple negative regulators of Wnt/beta-catenin signaling, including SFRP1, GSK3beta, TLE3 and NKD1, and that NKD1 is a major functional target of miR-744. PMID: 28107193
    5. NKD1 showed significantly increased level after induction chemotherapy achieved complete remission in follow-up paired acute myeloid leukemia patients ( p < 0.001). These findings indicated that reduced NKD1 expression is associated with unfavorable clinical outcome in cytogenetically normal acute myeloid leukemia. PMID: 28443469
    6. Low NKD1 expression is associated with hepatocellular carcinoma. PMID: 27507614
    7. Silencing of NKD1 significantly inhibited the proliferation and invasion of osteosarcoma cells. PMID: 28032380
    8. Suggest that NKD1 plays an important role in invasion in human breast cancer and it appears to be a potential prognostic marker for patients with breast cancer. PMID: 26097589
    9. Reduced NKD1 protein expression correlates with a poor prognosis in NSCLC PMID: 21599923
    10. Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling PMID: 19956716

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane. Cytoplasm.
  • 蛋白家族：
    NKD family
  • 組織特異性：
    Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen.
  • 數據庫鏈接：

    HGNC: 17045

    OMIM: 607851

    KEGG: hsa:85407

    STRING: 9606.ENSP00000268459

    UniGene: Hs.187578



主站蜘蛛池模板： 人人爽久久久噜噜噜婷婷| 欧美高清freexxxx性| 久久男人av资源站| 国产乱人伦偷精品视频下| 人妻中文乱码在线网站| 色狠狠成人综合网| 欧美国产日产一区二区| 欧美亚洲日本国产黑白配| 国产精品玩偶在线观看| 精品久久人人爽天天玩人人妻 | 亚洲乱码一区二区三区在线观看| 国产亚洲精品aaaa片小说| 久久亚洲精品国产精品777777| 人妻老妇乱子伦精品无码专区| 国产精品毛片一区二区三区| 99久久99久久精品国产片| 伊人久久大香线蕉av最新| 亚洲日韩一中文字暮av| 真人二十三式性视频(动)| 黑人糟蹋人妻hd中文字幕| 在线观看潮喷失禁大喷水无码| 国产女人高潮抽搐喷水视频| 新国产三级视频在线播放| 亚洲国产成人综合一区二区三区 | 777米奇影院狠狠色| 极品美女扒开粉嫩小泬| 18禁美女黄网站色大片免费看| 男女猛烈xx00免费视频试看| 护士的小嫩嫩好紧好爽| 男女裸交无遮挡啪啪激情试看 | 国产午夜福利在线观看视频| √8天堂资源地址中文在线| 国产午夜成人无码免费| 一本大道东京热无码| 风流老熟女一区二区三区| 2021最新精品国自产拍视频| 亚洲午夜福利院在线观看| 精品国产美女福到在线不卡 | 亚洲丁香五月激情综合| 亚洲精品毛片一区二区三区| 日日狠狠久久8888偷偷色|