在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NKD1 Antibody, Biotin conjugated

  • 中文名稱:
    NKD1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA853369LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) NKD1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    NKD1 antibody; NKD antibody; PP7246 antibody; Protein naked cuticle homolog 1 antibody; Naked-1 antibody; hNkd antibody; hNkd1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein naked cuticle homolog 1 protein (269-384AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cell autonomous antagonist of the canonical Wnt signaling pathway. May activate a second Wnt signaling pathway that controls planar cell polarity.
  • 基因功能參考文獻:
    1. the downregulation of NKD1 may be involved in the proliferation and migration of osteosarcoma cells through the activation of the canonical Wnt signaling pathway. PMID: 29115501
    2. The NKD1/Rac1 feedback loop regulates the invasion and migration ability of hepatocellular carcinoma cells. PMID: 27231134
    3. HNF1A-AS1 promoted HCC cell proliferation by repressing the NKD1 and p21 expression. PMID: 28292020
    4. Data indicate that microRNA miR-744 activated Wnt/beta-catenin pathway by targeting multiple negative regulators of Wnt/beta-catenin signaling, including SFRP1, GSK3beta, TLE3 and NKD1, and that NKD1 is a major functional target of miR-744. PMID: 28107193
    5. NKD1 showed significantly increased level after induction chemotherapy achieved complete remission in follow-up paired acute myeloid leukemia patients ( p < 0.001). These findings indicated that reduced NKD1 expression is associated with unfavorable clinical outcome in cytogenetically normal acute myeloid leukemia. PMID: 28443469
    6. Low NKD1 expression is associated with hepatocellular carcinoma. PMID: 27507614
    7. Silencing of NKD1 significantly inhibited the proliferation and invasion of osteosarcoma cells. PMID: 28032380
    8. Suggest that NKD1 plays an important role in invasion in human breast cancer and it appears to be a potential prognostic marker for patients with breast cancer. PMID: 26097589
    9. Reduced NKD1 protein expression correlates with a poor prognosis in NSCLC PMID: 21599923
    10. Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling PMID: 19956716

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane. Cytoplasm.
  • 蛋白家族:
    NKD family
  • 組織特異性:
    Expressed in colon, heart, kidney, leukocyte, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine and spleen.
  • 數據庫鏈接:

    HGNC: 17045

    OMIM: 607851

    KEGG: hsa:85407

    STRING: 9606.ENSP00000268459

    UniGene: Hs.187578



主站蜘蛛池模板: 天天av天天av天天透| 国内精品视这里只有精品| 全部av―极品视觉盛宴| 欧洲免费无线码在线一区| 18禁无遮挡羞羞污污污污免费| 免费无码又爽又刺激毛片| 14萝自慰专用网站| 国产成人一区二区三区别| 人妻免费一区二区三区最新| 欧美综合乱图图区乱图图区| 国产精品人成视频免费国产| 欧美日本韩国亚洲| 久久不见久久见中文字幕免费| 欧美日韩精品无码一本二本三本色 | 国产精品原创巨作av| 亚洲成h人av无码动漫无遮挡| 国产午夜无码片在线观看影视| 日韩欧美群交p片內射中文| 国产成人精品123区免费视频| 最近中文2019字幕第二页| 风韵犹存丰满大屁股熟妇视频 | 国产素人在线观看人成视频| 国产午夜高清高清在线观看| 久久婷婷成人综合色| 肉岳疯狂69式激情的高潮| 天天狠天天天天透在线| 亚洲va天堂va欧美ⅴa在线| 无码人妻一区二区三区免费n鬼逝 好爽好湿好硬好大免费视频 | 综合网日日天干夜夜久久| 国产午夜亚洲精品区| 国产一区二区三区在线视頻| 午夜福利免费0948视频| 亚洲精品nv久久久久久久久久 | 人妻体内射精一区二区| 亚洲国产成人av人片久久| 国产成 人 综合 亚洲| 成人做爰69片免费看网站野花| 欧美成人精品高清视频在线观看 | 成在人线av无码免费高潮喷水| 中国猛少妇色xxxxx| www国产亚洲精品|