在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. NFKBIL1 Antibody

NFKBIL1 Antibody

  • 中文名稱：
    NFKBIL1兔多克隆抗體
  • 貨號：
    CSB-PA887001LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA887001LA01HU diluted at 1:600 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) NFKBIL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    NFKBIL1
  • 別名：
    NFKBIL1 antibody; IKBL antibody; NF-kappa-B inhibitor-like protein 1 antibody; Inhibitor of kappa B-like protein antibody; I-kappa-B-like protein antibody; IkappaBL antibody; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human NF-kappa-B inhibitor-like protein 1 protein (185-312AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，NFKBIL1 Antibody (CSB-PA887001LA01HU)，的標記方式是Non-conjugated。對于NFKBIL1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA887001LB01HU NFKBIL1 Antibody, HRP conjugated ELISA
    FITC CSB-PA887001LC01HU NFKBIL1 Antibody, FITC conjugated
    Biotin CSB-PA887001LD01HU NFKBIL1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli.
  • 基因功能參考文獻：
    1. genetic association studies in a population of black women in South Africa: Data suggest that an SNP in NFKBIL1 (rs2071592) is associated with iron status/iron-deficiency anemia in the population studied. PMID: 25809685
    2. These observations suggest a functional involvement of IkappaBL in the regulation of alternative splicing in both human and viral genes, which is a novel link of HLA locus to the regulation of immunity and infection in humans. PMID: 23953137
    3. an association was noted between IKBL-62T and idiopathic inflammatory myopathy, with increased risk noted in anti-Jo-1- and -PM-Scl antibody-positive patients; the IKBL-62T association is dependent on TNF-308A and HLA-B*08, due to strong shared linkage disequilibrium between these alleles PMID: 22210660
    4. results do not provide evidence for the association between the -62A/T NFKBIL1 polymorphism and obsessive-compulsive disorder in this Brazilian sample. PMID: 19578685
    5. Results of the present study do not provide evidence for the association between the NFKBIL1 exon 4 polymorphism and MS predisposition in the investigated Polish population. PMID: 20568399
    6. The DPB1 gene controlled the severity of the vascular lesion, whereas the IKBL gene (NFKBIL1) was associated with a relatively mild phenotype. PMID: 19165231
    7. identifed the second rheumatoid arthritis -susceptibility locus within the HLA region, as the T allele of SNP 96452 (T/A), in the promoter region (position -62) of the I kappa BL gene (P=.0062) PMID: 12509789
    8. study shows that the estimated haplotype IkBL -421 8T/-62 T tends to be associated with susceptibility to rheumatoid arthritis in Taiwan PMID: 16644022
    9. no association between polymorphisms and hypertension, myocardial infarct and angina in Irish PMID: 17485095
    10. Minor homozygous genotypes of polymorphisms in NFKBIL1 were associated with moderately protective effects against myocardial infarction. PMID: 17517687
    11. The IKBL locus itself or another critical gene in this region may confer susceptibility to the development of chronic Chagas cardiomyopathy. PMID: 17544510
    12. IL1RN VNTR and the IKBL + 738T > C gene polymorphisms are not risk factors for myocardial infarct in Caucasians with type 2 diabetes PMID: 17847930
    13. A potential role for NFkBL1 in the pathogenesis of rheumatoid arthritis and in mRNA processing or the regulation of translation. PMID: 17855452
    14. IkappaBL allele polymorphisms influences risk of acquiring systemic lupus erythematosus and Sjogren's syndrome. PMID: 18295675

    顯示更多

    收起更多

  • 相關疾病：
    Rheumatoid arthritis (RA)
  • 亞細胞定位：
    Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus.
  • 組織特異性：
    Detected in different cell types including monocytes, T-cells, B-cells and hepatocytes.
  • 數據庫鏈接：

    HGNC: 7800

    OMIM: 180300

    KEGG: hsa:4795

    STRING: 9606.ENSP00000365318

    UniGene: Hs.2764



主站蜘蛛池模板： 国产午夜福利精品一区| 久久se精品一区精品二区| 小雪好紧好滑好湿好爽视频| 成人做爰高潮片免费视频| 8x国产精品视频| 国产精品爽爽久久久久久蜜臀| 99久久精品美女高潮喷水| 99久久无色码中文字幕人妻 | 老熟妇仑乱一区二区视頻| 中文字幕精品久久久久人妻红杏ⅰ| 女人高潮抽搐潮喷小视频| 宝贝腿开大点我添添公视频免费| 五月av综合av国产av| 成人精品一区日本无码网站| 亚洲乱码av中文一区二区软件| 顶级少妇做爰视频在线观看| 国产丰满麻豆videossexhd | 国产成人无码精品午夜福利a| 五月婷婷激情第四季| 亚洲精品国男人在线视频| 国产成人精品久久| 亚洲乱码国产乱码精品精大量| 国产白丝精品爽爽久久久久久蜜臀| 国产精品9999久久久久| 久久综合五月丁香六月丁香 | 在线观看成人无码中文av天堂| 久久精品国产大片免费观看| 四虎永久免费地址入口| 无码人妻精品一区二区三区下载| 亚洲精品一区二区三区四区乱码| 亚洲日韩激情无码一区| 偷窥村妇洗澡毛毛多| 天堂无码人妻精品一区二区三区| 天天弄天天模| 一本一道中文字幕无码东京热| 大伊香蕉精品视频在线直播| 色婷婷一区二区三区四区成人网| 性强烈的欧美三级视频| 亚洲欧美综合精品成人网站| 国产乱人伦精品一区二区| 在线亚洲精品国产一区麻豆|