在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

NFIX Antibody, HRP conjugated

  • 中文名稱:
    NFIX兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA617941LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) NFIX Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    NFIX
  • 別名:
    CCAAT box binding transcription factor antibody; CCAAT-box-binding transcription factor antibody; CTF antibody; NF-I/X antibody; NF1-X antibody; NF1A antibody; NF1X antibody; NFI X antibody; NFI-X antibody; NFI/X antibody; NFIX antibody; NFIX_HUMAN antibody; Nuclear factor 1 X type antibody; Nuclear factor 1 X-type antibody; Nuclear factor 1/X antibody; Nuclear factor I/X antibody; TGGCA binding protein antibody; TGGCA-binding protein antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Nuclear factor 1 X-type protein (201-440AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
  • 基因功能參考文獻:
    1. Microduplications encompassing NFIX cause intellectual disability, short stature and small head circumference. PMID: 29184170
    2. Compared to noncancerous esophageal mucosa, miR-1290 expression was upregulated, while NFIX mRNA expression was downregulated in ESCC tissues. Data suggest that the dysregulation of miR-1290-NFIX axis may play crucial roles in esophageal carcinogenesis and progression. PMID: 28800311
    3. A novel de novo pathogenic variant in the NFIX gene identified in a case of Marshall-Smith syndrome with precocious puberty and aortic root dilatation. PMID: 28442439
    4. Plasma miR-1914* and -1915 interact with NFIX RNA. PMID: 26695693
    5. Report novel mutations of NFIX gene causing Marshall-Smith syndrome or Sotos-like syndrome. PMID: 26200704
    6. miR-1290 functions as a tumor oncogene in the progression of esophageal squamous cell carcinoma by targeting NFIX PMID: 26653554
    7. NFIX analysis should be considered in patients presenting with overgrowth, macrocephaly and developmental delay including those in whom Sotos syndrome has been considered clinically but are negative for pathogenic NSD1 variants. PMID: 25118028
    8. Deletions in the 3' part of the NFIX gene including a recurrent Alu-mediated deletion of exon 6 and 7 account for previously unexplained cases of Marshall-Smith syndrome. PMID: 24924640
    9. missense mutations in NFIX were able to cause Sotos-like features. PMID: 22301465
    10. DNA methylation shows genome-wide association of NFIX, RAPGEF2 and MSRB3 with gestational age at birth. PMID: 22422452
    11. NFI-X3 and STAT3 control the migration of differentiating astrocytes as well as migration and invasion of glioma cells via regulating YKL-40 expression. PMID: 21953450
    12. NFI-X3 activates GFAP expression, in part, by inducing alterations in the nucleosome architecture that lead to the increased recruitment of RNA polymerase II PMID: 21189253
    13. These findings demonstrate that allelic NFIX mutations trigger distinct phenotypes, depending specifically on their impact on nonsense-mediated mRNA decay. PMID: 20673863
    14. Nuclear factor IA may play a role in astrocytoma biology. PMID: 20150379
    15. NFI-X cooperates with (activator protein 1)AP-1 by an unknown mechanism in astrocytes, which results in the expression of a subset of astrocyte-specific genes. PMID: 16565071
    16. temporal and dose-dependent interference by an AP-1 family member, c-Jun, upon NF-1 proteins binding an NF-1 consensus site derived from JC virus promoter sequence PMID: 16928756
    17. First report of structural alterations of the NFIA gene in hematopoietic diseases (polycythemia vera and chronic myelomonocytic leukemia, type 1). PMID: 18754024
    18. an expression program of NFIs is executed during the differentiation of astrocytes, with NFI-X and -C controlling the expression of astrocytic markers at late stages of differentiation. PMID: 19418463

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Sotos syndrome 2 (SOTOS2); Marshall-Smith syndrome (MRSHSS)
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    CTF/NF-I family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 7788

    OMIM: 164005

    KEGG: hsa:4784

    STRING: 9606.ENSP00000380781

    UniGene: Hs.257970



主站蜘蛛池模板: 成在人线av无码免费看网站| 亚洲国产婷婷综合在线精品| 成人免费乱码大片a毛片| 丰满岳乱妇久久久| 性欧美大战久久久久久久久| 中文字幕无线码一区2020青青| 人妻少妇av无码一区二区| 天堂а√在线最新版中文| 国产无遮挡又黄又爽动态图| 亚洲精品成人av在线| 波多野结衣在线观看一码 | 亚洲欧美色一区二区三区| 日韩人妻精品一区二区三区视频| 国产av中文av无码av狼人| 国产精品欧美久久久久无广告| 国产精品免费看久久久无码| 在线看片人成视频免费无遮挡| 寂寞少妇做spa按摩无码| 天无日天天射天天视| 99精品国产高清一区二区麻豆| 免费无码肉片在线观看| 国产一区二区三区乱码在线观看| 色综合久久久久无码专区| 亚 洲 成 人 网站在线观看| 国产无遮挡a片又黄又爽漫画 | 亚洲欧美日韩国产精品一区| 亚洲国产精品一区二区成人片| 日韩va中文字幕无码电影| 亚洲国产高清av网站| 人人澡人人妻人人爽人人蜜桃麻豆 | 久久综合丝袜日本网| 国产成人精品久久久久精品日日| 真实国产乱子伦对白在线播放 | 久久精品国产精品亚洲色婷婷| 97一区二区国产好的精华液| 特黄做受又大又粗又长大片| 亚洲色无码中文字幕手机在线| 无套内谢孕妇毛片免费看看| 亚洲欧美国产毛片在线| 国产成人剧情av麻豆果冻| 最新在线精品国自产拍福利|