在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MYBPC1 Antibody

MYBPC1 Antibody

  • 中文名稱：
    MYBPC1兔多克隆抗體
  • 貨號：
    CSB-PA010297
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of 293 cells using MYBPC1 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MYBPC1
  • 別名：
    C protein, skeletal muscle slow isoform antibody; C-protein antibody; MYBPC1 antibody; MYBPCC antibody; MYBPCS antibody; Myosin binding protein C, slow type antibody; Myosin-binding protein C antibody; MYPC1_HUMAN antibody; skeletal muscle C protein antibody; skeletal muscle slow isoform antibody; Slow MyBP C antibody; Slow MyBP-C antibody; slow-type antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human MYBPC1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. Slow skeletal protein that binds to both myosin and actin. In vitro, binds to native thin filaments and modifies the activity of actin-activated myosin ATPase. May modulate muscle contraction or may play a more structural role.
  • 基因功能參考文獻：
    1. A novel milder MYBPC1 homozygous phenotype causes arthrogryposis multiplex congenita in a consanguineous Israeli Druze pedigree. PMID: 26661508
    2. Ca(2+) modulates the interaction of cMyBP-C with the thin filament in the sarcomere. PMID: 26831109
    3. Two novel mutations in myosin binding protein C slow causing distal arthrogryposis type 2 were both found to occur in the C2 immunoglobulin domain, which constitutes part of the binding site for the S2 subfragment of myosin. PMID: 25679999
    4. Mutations in the MYH7 gene, rather than in the MYBPC3 gene, were also related to a worse prognosis. This is the first work characterizing HC molecular epidemiology in the Brazilian population for the 3 most important genes. PMID: 24093860
    5. Autosomal recessive lethal congenital contractural syndrome type 4 (LCCS4) caused by a mutation in MYBPC1 PMID: 22610851
    6. Significant molecule MYBPC1 phosphoprotein network from 12 frontal cortex of HIV encephalitis (HIVE) control patients and 16 HIVE, was identified and constructed. PMID: 21061152
    7. MyBPC1 acts as an adaptor to connect the ATP consumer (myosin) and the regenerator (muscle type creatine kinase) for efficient energy metabolism and homoeostasis. PMID: 21426302
    8. These findings reveal that the MYBPC1 is a novel gene responsible for DA1, though the mechanism of disease may differ from how some cardiac MYBPC3 mutations cause hypertrophic cardiomyopathy. PMID: 20045868
    9. Screening patients with dilated cardiomyopathy, as well as hypertrophic cardiomyopathy, for this mutation is of signifiant importance with this mutation diagnosing dilated cardiomyopathy. PMID: 12628722
    10. The present study demonstrates slow skeletal muscle type C-protein in moderate amount in right atrium and interatrial septum of adult human, rabbit, rat and bovine hearts using both immunocytochemical and immunoblotting procedures. PMID: 16003462
    11. to determine whether HCM mutations in beta myosin heavy chain located within the light meromyosin portion alter the binding of cMyBP-C, and to define the precise region of this binding. PMID: 16918501

    顯示更多

    收起更多

  • 相關疾病：
    Arthrogryposis, distal, 1B (DA1B); Lethal congenital contracture syndrome 4 (LCCS4)
  • 蛋白家族：
    Immunoglobulin superfamily, MyBP family
  • 數據庫鏈接：

    HGNC: 7549

    OMIM: 160794

    KEGG: hsa:4604

    STRING: 9606.ENSP00000354849

    UniGene: Hs.654589



主站蜘蛛池模板： 亚洲人成网站在线播放2019| 极品粉嫩国产18尤物在线观看| 国产精品成人久久电影| 亚洲国产午夜精品理论片妓女| 2019亚洲午夜无码天堂| 国产乱子伦在线一区二区| 亚洲精品午夜国产va久久成人| 中文字幕亚洲无线码| 69久久精品无码一区二区| 欧美一性一乱一交一视频| 大陆国产乱人伦| 国产吃奶在线观看| 国内精品视频一区二区三区 | 国产精品免费大片| 久久久久国产精品人妻| 亚洲欧洲无卡二区视頻| 无码av岛国片在线播放| √天堂资源中文| 嫩草av久久伊人妇女超级a| 国产精品 无码专区| 久久婷婷五月综合色首页| a毛片免费全部播放自慰| 又粗又长又硬义又黄又爽| 久久亚洲一区二区三区四区| 亚洲色欲www综合网| 鲁鲁夜夜天天综合视频| 国产天堂亚洲国产碰碰| 国产99久久久国产精品～～牛 | 热99re久久精品国产首页免费| 国产福利一区二区麻豆| 亚洲人成网线在线播放va蜜芽| 久久人人爽人人爽人人爽| 日日噜噜夜夜狠狠久久无码区| 少妇无码精油按摩专区| 粗大的内捧猛烈进出| 玩弄少妇高潮ⅹxxxyw| 天天做天天欢摸夜夜摸狠狠摸| 久久久国产精品麻豆a片| 国产av一区最新精品| 成 人色 网 站 欧美大片在线观看| 婷婷激情综合色五月久久竹菊影视|