在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MYBPC1 Antibody, FITC conjugated

  • 中文名稱:
    MYBPC1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA717389LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MYBPC1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MYBPC1
  • 別名:
    C protein, skeletal muscle slow isoform antibody; C-protein antibody; MYBPC1 antibody; MYBPCC antibody; MYBPCS antibody; Myosin binding protein C, slow type antibody; Myosin-binding protein C antibody; MYPC1_HUMAN antibody; skeletal muscle C protein antibody; skeletal muscle slow isoform antibody; Slow MyBP C antibody; Slow MyBP-C antibody; slow-type antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Myosin-binding protein C, slow-type protein (618-779AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. Slow skeletal protein that binds to both myosin and actin. In vitro, binds to native thin filaments and modifies the activity of actin-activated myosin ATPase. May modulate muscle contraction or may play a more structural role.
  • 基因功能參考文獻:
    1. A novel milder MYBPC1 homozygous phenotype causes arthrogryposis multiplex congenita in a consanguineous Israeli Druze pedigree. PMID: 26661508
    2. Ca(2+) modulates the interaction of cMyBP-C with the thin filament in the sarcomere. PMID: 26831109
    3. Two novel mutations in myosin binding protein C slow causing distal arthrogryposis type 2 were both found to occur in the C2 immunoglobulin domain, which constitutes part of the binding site for the S2 subfragment of myosin. PMID: 25679999
    4. Mutations in the MYH7 gene, rather than in the MYBPC3 gene, were also related to a worse prognosis. This is the first work characterizing HC molecular epidemiology in the Brazilian population for the 3 most important genes. PMID: 24093860
    5. Autosomal recessive lethal congenital contractural syndrome type 4 (LCCS4) caused by a mutation in MYBPC1 PMID: 22610851
    6. Significant molecule MYBPC1 phosphoprotein network from 12 frontal cortex of HIV encephalitis (HIVE) control patients and 16 HIVE, was identified and constructed. PMID: 21061152
    7. MyBPC1 acts as an adaptor to connect the ATP consumer (myosin) and the regenerator (muscle type creatine kinase) for efficient energy metabolism and homoeostasis. PMID: 21426302
    8. These findings reveal that the MYBPC1 is a novel gene responsible for DA1, though the mechanism of disease may differ from how some cardiac MYBPC3 mutations cause hypertrophic cardiomyopathy. PMID: 20045868
    9. Screening patients with dilated cardiomyopathy, as well as hypertrophic cardiomyopathy, for this mutation is of signifiant importance with this mutation diagnosing dilated cardiomyopathy. PMID: 12628722
    10. The present study demonstrates slow skeletal muscle type C-protein in moderate amount in right atrium and interatrial septum of adult human, rabbit, rat and bovine hearts using both immunocytochemical and immunoblotting procedures. PMID: 16003462
    11. to determine whether HCM mutations in beta myosin heavy chain located within the light meromyosin portion alter the binding of cMyBP-C, and to define the precise region of this binding. PMID: 16918501

    顯示更多

    收起更多

  • 相關疾病:
    Arthrogryposis, distal, 1B (DA1B); Lethal congenital contracture syndrome 4 (LCCS4)
  • 蛋白家族:
    Immunoglobulin superfamily, MyBP family
  • 數據庫鏈接:

    HGNC: 7549

    OMIM: 160794

    KEGG: hsa:4604

    STRING: 9606.ENSP00000354849

    UniGene: Hs.654589



主站蜘蛛池模板: 国产99视频精品专区| 久久不见久久见中文字幕免费| 午夜精品久久久内射近拍高清 | 特黄做受又粗又长又大又硬| 人妻精品久久无码区| 久久亚洲熟女cc98cm| 无码福利一区二区三区| 国内偷自第一区二区三区| 蜜芽av无码精品国产午夜| 久久精品国产久精久精| 澳门永久av免费网站| 人人做人人妻人人精| 国产精品国产三级国产剧情| 美女18禁一区二区三区视频| 亚洲精品一区二区久久| 久久精品亚洲一区二区三区浴池| 国产精品久久人妻无码网站蜜臀| 无码中文av波多野结衣一区| 午夜视频体内射.com.com| 亚洲国色天香卡2卡3卡4 | 欧美熟妇性xxx交潮喷| ww国产内射精品后入国产| 51社区精品视频| 国产成+人+综合+亚洲欧美| 玩两个丰满老熟女| 国产福利视频| 亚洲欧洲日产韩国在线看片| 亚洲区激情区无码区日韩区| 国产精品国产高清国产av| 国产喷水福利在线视频| 久久精品亚洲乱码伦伦中文| 国产精品毛片一区二区三区| 日本电影一区二区三区| 激情射精爆插热吻无码视频| 亚洲精品无码aⅴ中文字幕蜜桃| 日本少妇毛茸茸高潮| 色情无码一区二区三区| 丰满人妻无奈张开双腿av| 国产欧美日韩va另类在线播放| 人妻精油按摩bd高清中文字幕| 亚洲香蕉网久久综合影视|