在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MTERF1 Antibody, Biotin conjugated

MTERF1 Antibody, Biotin conjugated

  • 中文名稱：
    MTERF1兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA811872LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MTERF1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MTERF1
  • 別名：
    mitochondrial antibody; Mitochondrial transcription termination factor 1 antibody; mTERF antibody; MTERF_HUMAN antibody; Transcription termination factor antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Transcription termination factor 1, mitochondrial protein (63-232AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Transcription termination activity appears to be polarized with highest specificity for transcripts initiated on the light strand.
  • 基因功能參考文獻(xiàn)：
    1. MTERF1 has the ability to accommodate alternate active conformations. PMID: 26523681
    2. It has been demonstrated that MTERF1 arrests mitochondrial DNA (mtDNA) replication with distinct polarity whereby MTERF1 acts as a directional contra-helicase, blocking mtDNA unwinding by the mitochondrial helicase TWINKLE. PMID: 27112570
    3. Studies indicate that the structure of the mitochondrial transcription termination factor (MTERF1) provides insight into the mechanism of binding, recognition of the termination sequence and the conformational changes involved in mediating termination. PMID: 21326908
    4. Single nucleotide polymorphism in MTERF gene is associated with epithelial ovarian cancer. PMID: 21447778
    5. data suggested that hMTERF4 is an essential factor for cell proliferation, which is probably modulated by mitochondrial transcription to promote cell proliferation PMID: 21450691
    6. Data show that mTERF protein levels materially affect the amount of readthrough transcription on the antisense strand of mtDNA, whilst the effects on sense-strand transcripts are complex, and suggest the influence of compensatory mechanisms. PMID: 20846394
    7. Presented are the crystal structures of human mitochondrial regulator MTERF, a transcription termination factor also implicated in replication pausing, in complex with double-stranded DNA oligonucleotides containing the tRNA(Leu)(UUR) gene sequence. PMID: 20543826
    8. The structure indicates that upon sequence recognition MTERF1 unwinds the DNA molecule, promoting eversion of three nucleotides. PMID: 20550934
    9. mTERF mRNA levels were higher in elite athletes compared with moderately active subjects PMID: 19681768
    10. mTERF exists in mitochondria in two forms, an active monomer and an inactive large size complex PMID: 14744862
    11. monomeric human mTERF is fully active in its non-phosphorylated form and that the protein does not require additional cellular factors to terminate mitochondrial transcription in vitro PMID: 15899902
    12. analysis of DNA light-strand preferential recognition of human mitochondria transcription termination factor mTERF PMID: 16336784
    13. Results indicate a role for mTERF in mtDNA replication, in addition to its role in transcription. PMID: 17884915

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    MTERF family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 21463

    OMIM: 602318

    KEGG: hsa:7978

    STRING: 9606.ENSP00000248643

    UniGene: Hs.532216



主站蜘蛛池模板： 日本韩国亚洲欧美在线| 超碰香蕉人人网99精品| 国内精品免费久久久久软件| 亚洲综合网站精品一区二区| 中文字幕有码无码人妻在线| 午夜亚洲国产理论片二级港台二级 | 色噜噜亚洲男人的天堂www| 欧美人与zoxxxx另类| 搡老熟女老女人一区二区| 精品无码av无码专区| 久久九九精品国产综合喷水| 无码人妻天天拍夜夜爽| 69综合精品国产二区无码| 99久久无码私人网站| 国产成人无码va在线观看| 亚洲无线码中文字幕在线| 1000部夫妻午夜免费| 秋霞国产午夜伦午夜福利片| 日本理论片午午伦夜理片2021| 在线精品亚洲第一区焦香| 超碰aⅴ人人做人人爽欧美| 国产suv精品一区二区五| 亚洲女教师丝祙在线播放| 人人妻人人妻人人人人妻人人| 成人无码精品1区2区3区免费看| 国产肥熟女视频一区二区三区| 欧美日韩国产亚洲沙发| 无码乱肉视频免费大全合集| 婷婷成人综合激情在线视频播放| 97色偷偷色噜噜狠狠爱网站97 | 久久精品国产精油按摩| 国产女人喷潮视频在线观看| 欧美性白人极品hd| 国产 精品 自在 线免费 | 香蕉精品亚洲二区在线观看| 正在播放熟妇群老熟妇456 | 久久高清超碰av热热久久| 99精品欧美一区二区三区| 日日摸日日添日日碰9学生露脸| 特黄做受又大又粗又长大片| 无码色av一二区在线播放|