在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MNAT1 Antibody

MNAT1 Antibody

  • 中文名稱：
    MNAT1兔多克隆抗體
  • 貨號：
    CSB-PA583349
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from HeLa cells, HepG2 cells and 293 cells, using MAT1 antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MNAT1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from internal of Human MAT1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
  • 基因功能參考文獻：
    1. Expressions of components of the CAK complex, CDK7, MAT1, and Cyclin H are elevated in breast cancer. PMID: 27301701
    2. The intrinsically programmed MAT1 expression and fragmentation regulate granulopoiesis. PMID: 23765726
    3. The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H. PMID: 12140753
    4. Retinoid-induced G1 arrest and differentiation activation are associated with a switch to enzyme hypophosphorylation of retinoic acid receptor alpha. PMID: 12213824
    5. interaction with MTA1 and role in regulating estrogen receptor transactivation functions PMID: 12527756
    6. In response to ATRA, PML/RARalpha is dissociated from CAK, leading to MAT1 degradation, G1 arrest, and decreased CAK phosphorylation of PML/RARalpha PMID: 16935935
    7. Retinoic-acid-induced RAR-CAK signaling events appear to proceed intrinsically during granulocytic development of normal primitive hematopoietic cells. ALDH-governed RA availability may mediate this process by initiating RAR-CAK signaling. PMID: 17628022
    8. These results suggested that genetic variants in CAK genes, Cdk7, cyclin H, MAT1, might modulate the risk of lung cancer in a gene-gene interaction mode, which consist to the biochemical interaction of corresponding proteins. PMID: 17707548

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes.
  • 數據庫鏈接：

    HGNC: 7181

    OMIM: 602659

    KEGG: hsa:4331

    STRING: 9606.ENSP00000261245

    UniGene: Hs.509523



主站蜘蛛池模板： 亚洲精品无码久久毛片波多野吉衣| 特级a欧美做爰片第一次| 色情无码www视频无码区澳门 | 久久精品亚洲精品无码白云tv| 亚洲国产欧美在线人成aaaa| 久久午夜神器| 性欧美高清come| 国产亚洲精品久久久久久久软件| 亚洲伊人久久综合成人| 亚洲国产精品久久久久秋霞小说| 亚洲人成网站18禁止一区| 激情无码人妻又粗又大| 熟女人妻一区二区三区免费看| 国产在线 | 欧洲| 电影久久久久久| 亚洲人成人无码网www电影首页| 久久精品无码专区免费| 奇米影视777四色米奇影院| 特黄 做受又硬又粗又大视频| 亚洲欧美日韩综合一区在线| 久久青青草免费线频观| 国产成人无码一区二区在线观看| 国产又大又粗又爽的毛片| 肉感饱满中年熟妇日本| 国模大尺度福利视频在线| 国产精品久久久久无码av| 中国女人和老外的毛片| 国产亚洲一卡2卡3卡4卡网站| 亚州日本乱码一区二区三区| 国产人成无码视频在线观看| 亚洲精品字幕在线观看| 亚洲аv电影天堂网| 国内高清a自拍视频| 国产精品视频一区二区三区不卡| 狠狠热精品免费视频| 精品无码久久久久国产手机版 | 国产真实夫妇交换视频| 免费观看四虎精品国产地址| 337p日本欧洲亚洲大胆69影院| 日本人妻丰满熟妇久久久久久| 欧美性黑人极品hd另类|