在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MNAT1 Antibody

MNAT1 Antibody

  • 中文名稱：
    MNAT1兔多克隆抗體
  • 貨號：
    CSB-PA014686GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    MNAT 1 antibody; CAP35 antibody; CDK activating kinase assembly factor MAT1 antibody; CDK-activating kinase assembly factor MAT1 antibody; CDK7/cyclin H assembly factor antibody; CDK7/cyclin-H assembly factor antibody; Cyclin G1 interacting protein antibody; Cyclin-G1-interacting protein antibody; MAT1 antibody; MAT1_HUMAN antibody; Menage a trois 1 (CAK assembly factor) antibody; Menage a trois antibody; Menage a trois homolog 1; cyclin H assembly factor (Xenopus laevis) antibody; MNAT CDK activating kinase assembly factor 1 antibody; Mnat1 antibody; p35 antibody; p36 antibody; RING finger protein 66 antibody; RING finger protein MAT1 antibody; RNF66 antibody; TFB3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human MNAT1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
  • 基因功能參考文獻：
    1. Expressions of components of the CAK complex, CDK7, MAT1, and Cyclin H are elevated in breast cancer. PMID: 27301701
    2. The intrinsically programmed MAT1 expression and fragmentation regulate granulopoiesis. PMID: 23765726
    3. The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H. PMID: 12140753
    4. Retinoid-induced G1 arrest and differentiation activation are associated with a switch to enzyme hypophosphorylation of retinoic acid receptor alpha. PMID: 12213824
    5. interaction with MTA1 and role in regulating estrogen receptor transactivation functions PMID: 12527756
    6. In response to ATRA, PML/RARalpha is dissociated from CAK, leading to MAT1 degradation, G1 arrest, and decreased CAK phosphorylation of PML/RARalpha PMID: 16935935
    7. Retinoic-acid-induced RAR-CAK signaling events appear to proceed intrinsically during granulocytic development of normal primitive hematopoietic cells. ALDH-governed RA availability may mediate this process by initiating RAR-CAK signaling. PMID: 17628022
    8. These results suggested that genetic variants in CAK genes, Cdk7, cyclin H, MAT1, might modulate the risk of lung cancer in a gene-gene interaction mode, which consist to the biochemical interaction of corresponding proteins. PMID: 17707548

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes.
  • 數據庫鏈接：

    HGNC: 7181

    OMIM: 602659

    KEGG: hsa:4331

    STRING: 9606.ENSP00000261245

    UniGene: Hs.509523



主站蜘蛛池模板： 西西人体做爰大胆gogo| 上海少妇高潮狂叫喷水了| 亚洲精品久久久狠狠爱小说 | 在线亚洲视频网站www色| 日本看片一二三区高清| 99久久国产露脸精品竹菊传媒| 中文字幕人妻熟女人妻| 亚洲欧美日韩成人一区| 亚洲vav在线男人的天堂| 国内少妇高潮嗷嗷叫在线播放 | 日日摸日日碰夜夜爽无码| 欧美精品一区二区三区在线| 久久综合伊人77777| 无码专区—va亚洲v专区vr| 国产免费福利在线视频| 性高湖久久久久久久久| 亚洲国产一区二区三区| 色欲天天婬色婬香综合网完整版| 女人19水真多免费毛片| 欧美影院成年免费版| 中文字幕乱码一区av久久不卡 | 宅男色影视亚洲人在线| 欧美日韩综合一区二区三区| 久久99精品国产麻豆婷婷| 美女扒开奶罩露出奶头视频网站| 亚洲a∨无码国产精品久久网| 国产人与禽zoz0性伦| 尤物国精品午夜福利视频| 国产卡1卡2卡3麻豆精品免费| 中文区中文字幕免费看| 国产男生午夜福利免费网站 | 久久久国产精品亚洲一区| 色哟哟国产精品免费观看| 丁香婷婷综合久久来来去| 久久精品国自产拍| 国产精品盗摄!偷窥盗摄| 熟妇人妻无码xxx视频| 久久99精品久久久久久2021| 欧洲美女粗暴牲交免费观看| 大肉大捧一进一出好爽app| 亚洲精品伦理熟女国产一区二区|