在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MLXIP Antibody

  • 中文名稱:
    MLXIP兔多克隆抗體
  • 貨號:
    CSB-PA862054LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA862054LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MLXIP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MLXIP
  • 別名:
    MLXIP antibody; BHLHE36 antibody; KIAA0867 antibody; MIR antibody; MONDOA antibody; MLX-interacting protein antibody; Class E basic helix-loop-helix protein 36 antibody; bHLHe36 antibody; Transcriptional activator MondoA antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human MLX-interacting protein (1-217AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,MLXIP Antibody (CSB-PA862054LA01HU),的標記方式是Non-conjugated。對于MLXIP Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA862054LB01HU MLXIP Antibody, HRP conjugated ELISA
    FITC CSB-PA862054LC01HU MLXIP Antibody, FITC conjugated
    Biotin CSB-PA862054LD01HU MLXIP Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
  • 基因功能參考文獻:
    1. Data (including data from studies in knockout mice) suggest that MONDOA shuttles to nucleus of pancreatic beta-cells where it is required for induction of glucose-responsive genes arrestin domain-containing protein 4 (ARRDC4) and thioredoxin interacting protein (TXNIP). PMID: 29282201
    2. MondoA-directed programs have a key role in the coordinated control of myocyte lipid balance and insulin signaling PMID: 27500491
    3. Evaluation of the conservation of ChREBP and MondoA sequences demonstrate that MondoA is better conserved and potentially mediates more ancient function in glucose metabolism. PMID: 26910886
    4. These results suggest that C771G polymorphism of MLXIPL gene is associated with coronary stenosis and its severity. PMID: 25179879
    5. Knockdown of MondoA, or its dimerization partner Mlx, blocks Myc-induced reprogramming of multiple metabolic pathways, resulting in apoptosis PMID: 25640402
    6. An important contribution of MondoA to leukemia aggressiveness, which makes MondoA a potential candidate for targeted treatment of acute lymphoblastic leukemia. PMID: 22748921
    7. Glucose is required at two additional steps to stimulate the transcription activation function of MondoA-Mlx complexes. PMID: 20385767
    8. Data show that for both MondoA and Mlx, the C-terminal domain CRM-1 has cytoplasmic localization activity that is required by the protein monomers to accumulate in the cytoplasm. PMID: 12446771
    9. Endogenous MondoA and Mlx associate with mitochondria in primary skeletal muscle. PMID: 16782875
    10. Data suggest that glutamine-dependent mitochondrial anapleurosis dictates glucose uptake and aerobic glycolysis by blocking MondoA:Mlx-dependent transcriptional activation of TXNIP. PMID: 19706488

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Mitochondrion outer membrane.
  • 組織特異性:
    Widely expressed in adult tissues. Most abundant in skeletal muscle.
  • 數據庫鏈接:

    HGNC: 17055

    OMIM: 608090

    KEGG: hsa:22877

    STRING: 9606.ENSP00000312834

    UniGene: Hs.437153



主站蜘蛛池模板: 国产精品人妻| 久久九九久精品国产免费直播| 深夜福利视频在线播放| 国产免费一区二区视频| 最近中文字幕免费大全在线| 国产山东熟女48嗷嗷叫| 青青草视频在线观看 | 伊人久久大香线蕉av综合| 2021无码天堂在线| 亚洲精品无码国产片| 人妻无码中文专区久久app| 日本道精品一区二区三区| 亚洲自偷自偷偷色无码中文| 无遮挡1000部拍拍拍免费| 色综合久久久久综合体桃花网| 日本亚洲vr欧美不卡高清专区| 精品国产在天天在线观看| 少妇高潮一区二区三区99| 欧洲-级毛片内射| 亚洲欧美人高清精品a∨| 中文字幕人乱码中文| 狠狠色噜噜狠狠狠狠av| 在线精品视频一区二区 | av无码免费永久在线观看| 欧美日韩精品一区二区三区不卡| 青草伊人久久综在合线亚洲观看| 日本免费一本一二区三区| 色悠久久久久综合网国产| 国产成人免费爽爽爽视频| 人人妻人人爽人人澡av| 欧美人禽zozo动人物杂交| 99亚洲男女激情在线观看| 丝袜无码一区二区三区| 国产精品久人妻精品老妇| 中文字幕美人妻亅u乚一596| 久久精品欧美日韩精品| 9l国产精品久久久久麻豆| 中文字幕资源网| 午夜寂寞少妇aaa片毛片| 欧美人禽杂交狂配免费看| 亚洲综合在线一区二区三区|