在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MLXIP Antibody

  • 中文名稱:
    MLXIP兔多克隆抗體
  • 貨號:
    CSB-PA862054LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA862054LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MLXIP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MLXIP
  • 別名:
    MLXIP antibody; BHLHE36 antibody; KIAA0867 antibody; MIR antibody; MONDOA antibody; MLX-interacting protein antibody; Class E basic helix-loop-helix protein 36 antibody; bHLHe36 antibody; Transcriptional activator MondoA antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human MLX-interacting protein (1-217AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,MLXIP Antibody (CSB-PA862054LA01HU),的標記方式是Non-conjugated。對于MLXIP Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA862054LB01HU MLXIP Antibody, HRP conjugated ELISA
    FITC CSB-PA862054LC01HU MLXIP Antibody, FITC conjugated
    Biotin CSB-PA862054LD01HU MLXIP Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
  • 基因功能參考文獻:
    1. Data (including data from studies in knockout mice) suggest that MONDOA shuttles to nucleus of pancreatic beta-cells where it is required for induction of glucose-responsive genes arrestin domain-containing protein 4 (ARRDC4) and thioredoxin interacting protein (TXNIP). PMID: 29282201
    2. MondoA-directed programs have a key role in the coordinated control of myocyte lipid balance and insulin signaling PMID: 27500491
    3. Evaluation of the conservation of ChREBP and MondoA sequences demonstrate that MondoA is better conserved and potentially mediates more ancient function in glucose metabolism. PMID: 26910886
    4. These results suggest that C771G polymorphism of MLXIPL gene is associated with coronary stenosis and its severity. PMID: 25179879
    5. Knockdown of MondoA, or its dimerization partner Mlx, blocks Myc-induced reprogramming of multiple metabolic pathways, resulting in apoptosis PMID: 25640402
    6. An important contribution of MondoA to leukemia aggressiveness, which makes MondoA a potential candidate for targeted treatment of acute lymphoblastic leukemia. PMID: 22748921
    7. Glucose is required at two additional steps to stimulate the transcription activation function of MondoA-Mlx complexes. PMID: 20385767
    8. Data show that for both MondoA and Mlx, the C-terminal domain CRM-1 has cytoplasmic localization activity that is required by the protein monomers to accumulate in the cytoplasm. PMID: 12446771
    9. Endogenous MondoA and Mlx associate with mitochondria in primary skeletal muscle. PMID: 16782875
    10. Data suggest that glutamine-dependent mitochondrial anapleurosis dictates glucose uptake and aerobic glycolysis by blocking MondoA:Mlx-dependent transcriptional activation of TXNIP. PMID: 19706488

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus. Mitochondrion outer membrane.
  • 組織特異性:
    Widely expressed in adult tissues. Most abundant in skeletal muscle.
  • 數據庫鏈接:

    HGNC: 17055

    OMIM: 608090

    KEGG: hsa:22877

    STRING: 9606.ENSP00000312834

    UniGene: Hs.437153



主站蜘蛛池模板: 欧美激欧美啪啪片| 欧洲熟妇色 欧美| 中文字幕在线观看| 久久久久国产精品人妻aⅴ天堂 | 久久国产精品无码hdav| 无码手机线免费观看| 激情97综合亚洲色婷婷五| 亚洲天天做日日做天天欢毛片| 7777奇米四色成人眼影| 国产人妖xxxx做受视频| 亚洲成亚洲成网| 国产精品久久久久影院亚瑟| 麻豆一区二区在我观看| 亚洲欧美日韩国产成人精品影院| 九九综合九色综合网站| 久久国产福利一区二区| 一区二区三区四区在线 | 欧洲| 人人添人人澡人人澡人人人人| 久久av高清无码| 久久久精品国产sm调教网站| 国产一卡三卡四卡无卡精品 | 亚洲国产成人av在线观看| 亚洲综合最新无码专区| 三级无码在钱av无码在钱 | 欧美精品无码一区二区三区| 午夜精品久久久久久久99热| 亚洲精品久久久一二三区| 色先锋影音岛国av资源| 性色欲情网站iwww九文堂| 亚洲国产精品第一区二区| 欧美一区内射最近更新| 真实国产乱子伦视频| 亚洲国产婷婷香蕉久久久久久| 在线综合亚洲欧洲综合网站| 亚洲最大激情中文字幕| 男女啪啪高清无遮挡免费| 人人妻人人澡人人爽不卡视频 | 国产精品国产三级在线...| 中国白嫩丰满人妻videos| 精品久久久无码人妻字幂| 青青爽无码视频在线观看|