在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MLXIP Antibody, Biotin conjugated

  • 中文名稱:
    MLXIP兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA862054LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) MLXIP Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MLXIP
  • 別名:
    MLXIP antibody; BHLHE36 antibody; KIAA0867 antibody; MIR antibody; MONDOA antibody; MLX-interacting protein antibody; Class E basic helix-loop-helix protein 36 antibody; bHLHe36 antibody; Transcriptional activator MondoA antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human MLX-interacting protein (1-217AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類(lèi)型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3'. Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation.
  • 基因功能參考文獻(xiàn):
    1. Data (including data from studies in knockout mice) suggest that MONDOA shuttles to nucleus of pancreatic beta-cells where it is required for induction of glucose-responsive genes arrestin domain-containing protein 4 (ARRDC4) and thioredoxin interacting protein (TXNIP). PMID: 29282201
    2. MondoA-directed programs have a key role in the coordinated control of myocyte lipid balance and insulin signaling PMID: 27500491
    3. Evaluation of the conservation of ChREBP and MondoA sequences demonstrate that MondoA is better conserved and potentially mediates more ancient function in glucose metabolism. PMID: 26910886
    4. These results suggest that C771G polymorphism of MLXIPL gene is associated with coronary stenosis and its severity. PMID: 25179879
    5. Knockdown of MondoA, or its dimerization partner Mlx, blocks Myc-induced reprogramming of multiple metabolic pathways, resulting in apoptosis PMID: 25640402
    6. An important contribution of MondoA to leukemia aggressiveness, which makes MondoA a potential candidate for targeted treatment of acute lymphoblastic leukemia. PMID: 22748921
    7. Glucose is required at two additional steps to stimulate the transcription activation function of MondoA-Mlx complexes. PMID: 20385767
    8. Data show that for both MondoA and Mlx, the C-terminal domain CRM-1 has cytoplasmic localization activity that is required by the protein monomers to accumulate in the cytoplasm. PMID: 12446771
    9. Endogenous MondoA and Mlx associate with mitochondria in primary skeletal muscle. PMID: 16782875
    10. Data suggest that glutamine-dependent mitochondrial anapleurosis dictates glucose uptake and aerobic glycolysis by blocking MondoA:Mlx-dependent transcriptional activation of TXNIP. PMID: 19706488

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus. Mitochondrion outer membrane.
  • 組織特異性:
    Widely expressed in adult tissues. Most abundant in skeletal muscle.
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 17055

    OMIM: 608090

    KEGG: hsa:22877

    STRING: 9606.ENSP00000312834

    UniGene: Hs.437153



主站蜘蛛池模板: 欧美老熟妇乱xxxxx| 久久久久国色av∨免费看| 天堂av成年av影视| 大地资源中文第三页| 久久婷婷五月综合色欧美| 无码成人片在线播放| 亚洲国产日韩制服在线观看| 国产极品粉嫩福利姬萌白酱| 欧美精品国产aⅴ一区二区在线| 久激情内射婷内射蜜桃人妖| 区二区三区国产精华液区别大吗| 欧美性猛交xxxx乱大交3| 亚洲熟妇久久精品| 欧美99久久无码一区人妻a片| 国产一区视频一区欧美| 无码国产69精品久久久孕妇| 怡红院免费的全部视频| 亚洲精品无码高潮喷水a片软| 亚瑟av亚洲精品一区二区| 欧美日韩在线视频| 亚洲无线观看国产精品| 国产精品亚洲а∨天堂| 亚洲人成网7777777国产| 日韩人妻熟女中文字幕a美景之屋| 日本xxxx色视频在线观看| 成人无码a∨电影免费| 免费又黄又硬又爽大片| 无码少妇一区二区三区芒果| 日韩制服国产精品一区| 欧美三级在线播放| 色婷婷狠狠久久综合五月| 国产如狼似虎富婆找强壮黑人| 国产乱子伦60女人的皮视频 | 中文国产成人精品久久不卡| 亚洲aⅴ综合色区无码一区| 真实国产乱子伦在线视频| 日本无遮挡吸乳视频| 国产精品亚洲一区二区三区喷水 | 欧美亚洲综合在线一区| 久久亚洲精品无码播放| 国产三级视频在线播放线观看|