在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MINK1 Antibody

MINK1 Antibody

  • 中文名稱：
    MINK1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA003241
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using MINK1 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    MINK1
  • 別名：
    MINK1 antibody; B55 antibody; MAP4K6 antibody; MINK antibody; YSK2 antibody; ZC3 antibody; Misshapen-like kinase 1 antibody; EC 2.7.11.1 antibody; GCK family kinase MiNK antibody; MAPK/ERK kinase kinase kinase 6 antibody; MEK kinase kinase 6 antibody; MEKKK 6 antibody; Misshapen/NIK-related kinase antibody; Mitogen-activated protein kinase kinase kinase kinase 6 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human MINK1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates: TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection of thymocytes, perhaps by coupling NCK1 to activation of JNK1.; Isoform 4 can activate the JNK pathway. Involved in the regulation of actin cytoskeleton reorganization, cell-matrix adhesion, cell-cell adhesion and cell migration.
  • 基因功能參考文獻(xiàn)：
    1. MINK plays a functional role in the IRES-mediated translation of EV71 viral RNA and may provide a potential target for the development of specific antiviral strategies against EV71 infection PMID: 25747578
    2. Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis. PMID: 22665485
    3. MINK1 interacts with and phosphorylates PRICKLE1 and PRICKLE2. PMID: 22037766
    4. MINK interaction with Rap2 plays a critical role in maintaining the morphological integrity of dendrites and synaptic transmission. PMID: 21048137
    5. Analysis of the coding region of the NIK gene in progressive supranuclear palsy (PSP) patients through single strand conformation polymorphism and direct sequencing does not support a pathogenic role of the NIK gene in PSP. PMID: 12668260
    6. results suggest that human Misshapen/NIKs-related kinase beta (hMINK beta) plays an important role in cytoskeleton reorganization, cell adhesion, and cell motility(hMINKbeta) PMID: 15469942

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cell junction, synapse, postsynaptic density. Cell projection, axon. Cell projection, dendrite.; [Isoform 4]: Golgi apparatus.
  • 蛋白家族：
    Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily
  • 組織特異性：
    Expressed in the brain, isoform 2 is more abundant than isoform 1. Isoform 3 is ubiquitously expressed. Isoform 1 is most abundant in the skeletal muscle. Isoform 4 is ubiquitously expressed with relative high levels in brain, skeletal muscle, pancreas an
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17565

    OMIM: 609426

    KEGG: hsa:50488

    STRING: 9606.ENSP00000347427

    UniGene: Hs.443417



主站蜘蛛池模板： 国产精品情侣呻吟对白视频 | 色一情一乱一伦一区二区三区小说| 国产经典三级av在线播放| 夜夜香夜夜摸夜夜添视频| 无套内内射视频网站| 亚洲乱亚洲乱妇| 日韩精品真人荷官无码| 国产成人综合久久免费| 亚洲熟妇av一区| 亚洲va在线∨a天堂va欧美va| 国产欧美高清在线观看| 中文字幕亚洲乱码熟女一区二区| 久久香蕉国产线看观看手机| 国产成熟女人性满足视频| 特级毛片内射www无码| 少妇高潮毛片色欲ava片| 久久本色成人综合网| 狠狠综合久久久久尤物| 精品蜜臀久久久久99网站| 人人澡人人透人人爽| 国语做受对白xxxxx在线| 亚洲精品国产一区二区在线观看| 欧美日韩不卡合集视频| 日产电影一区二区三区| 1000部又爽又黄无遮挡的视频| 天天av天天av天天透| 亚洲小说春色综合另类| 亚洲2022国产成人精品无码区| 麻豆av字幕无码中文| 亚洲国产成人无码精品| 国产精品一品二区三区的使用体验| 九个美女露脸撒尿嘘嘘视频| 亚洲国产成人高清影视| 大胆欧美熟妇xx| 性夜夜春夜夜爽aa片a | 人妻少妇-嫩草影院| 成人无码在线视频网站| 一本一久本久a久久精品综合| 57pao成人国产永久免费视频| 亚洲久久中文字幕www网站| 丁香五月综合久久激情|