在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MIEF1 Antibody, HRP conjugated

MIEF1 Antibody, HRP conjugated

  • 中文名稱：
    MIEF1兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA873622LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MIEF1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MIEF1
  • 別名：
    MIEF1 antibody; MID51 antibody; SMCR7L antibody; Mitochondrial dynamics protein MID51 antibody; Mitochondrial dynamics protein of 51 kDa antibody; Mitochondrial elongation factor 1 antibody; Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like antibody; SMCR7-like protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Mitochondrial dynamics protein MID51 protein (51-309AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.
  • 基因功能參考文獻：
    1. MiD51 inhibits Drp1, whereas ADP promotes MiD51-mediated fission. [review] PMID: 27660309
    2. The results indicate that Drp1-dependent mitochondrial fission through MiD49/MiD51 regulates cristae remodeling during intrinsic apoptosis. PMID: 26903540
    3. The cytoplasmic domain of MiD51 was overexpressed, purified and crystallized. PMID: 24817717
    4. MIEF1 and MIEF2 are differentially expressed in human tissues during development PMID: 23880462
    5. MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and suggest that they provide specificity to the division of mitochondria. PMID: 23921378
    6. we find that either MiD49 or MiD51 can mediate Drp1 recruitment and mitochondrial fission in the absence of Fis1 and Mff PMID: 23283981
    7. elevated MIEF1 levels induce mitochondrial fusion; depletion of MIEF1 causes mitochondrial fragmentation; MIEF1 interacts with and recruits Drp1 to mitochondria but inhibits Drp1 activity, executing a negative effect on mitochondrial fission PMID: 21701560
    8. MiD49/51 are new mediators of mitochondrial division affecting Drp1 action at mitochondria. PMID: 21508961
    9. Mitochondrial outer membrane protein that recruits fission mediator Drp1 to the mitochondrial surface. PMID: 21508961

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion outer membrane; Single-pass membrane protein.
  • 蛋白家族：
    SMCR7 family
  • 組織特異性：
    Expression is relatively high in heart, skeletal muscle, pancreas and kidney.
  • 數據庫鏈接：

    HGNC: 25979

    OMIM: 615497

    KEGG: hsa:54471

    STRING: 9606.ENSP00000327124

    UniGene: Hs.728085



主站蜘蛛池模板： 狠日狠干日日射| 成人网站免费大全日韩国产| 老子午夜理论影院理论| 国模国产精品嫩模大尺度视频| 欧美人与动性xxxxbbbb| 亚欧色一区w666天堂| 亚洲精品无码久久千人斩| 伊人成伊人成综合网222| 国产乱人伦偷精精品视频| 肥老熟妇伦子伦456视频| 乱码人妻一区二区三区| 人妻丰满熟妇av无码处处不卡| 真人床震高潮全部视频免费| 欧美黑人巨大xxxxx| 中年人妻丰满av无码久久不卡 | 色综合色欲色综合色综合色综合r 四虎亚洲欧美成人网站 | 日韩精品人妻系列无码专区免费| 永久免费的av在线电影网| 青青草免费国产线观720| 亚洲多毛妓女毛茸茸的| 欧美成人免费全部| 免费无码作爱视频| а天堂中文在线官网在线| 极品少妇被后入内射视| 免费全部高h视频无码| 无码专区6080yy国产电影| 国产精品a无线| 97夜夜澡人人爽人人喊a| 亚洲精品无码mv在线观看网站| 99久久免费国产精精品| 精品无码国产自产拍在线观看蜜| 国产精品久久自在自线不卡| 午夜福利av无码一区二区| 娇妻玩4p被三个男人伺候电影| 婷婷五月深爱憿情网| 四虎免费最新在线永久4hu| 波多野结衣中文字幕一区二区三区 | 无码av最新无码av专区| 人妻少妇无码专视频在线| 日本一区二区在线播放| 精品成人免费一区二区不卡|