在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MAT2B Antibody, Biotin conjugated

  • 中文名稱:
    MAT2B兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA882157LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MAT2B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    1110064C04Rik antibody; 2410018D16Rik antibody; AI182287 antibody; AU022853 antibody; Beta regulatory subunit of methionine adenosyltransferase antibody; dTDP 4 keto 6 deoxy D glucose 4 reductase antibody; DTDP-4-keto-6-deoxy-D-glucose 4-reductase antibody; MAT II antibody; MAT II beta antibody; Mat2b antibody; MAT2B_HUMAN antibody; MATIIbeta antibody; Methionine adenosyltransferase 2 beta subunit antibody; Methionine adenosyltransferase 2 subunit beta antibody; Methionine adenosyltransferase II beta antibody; MGC12237 antibody; MSTP045 antibody; Nbla02999 antibody; OTTMUSP00000005600 antibody; Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase antibody; Putative protein product of Nbla02999 antibody; RP23-382C18.2 antibody; SDR23E1 antibody; Short chain dehydrogenase/reductase family 23E member 1 antibody; TGR antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Methionine adenosyltransferase 2 subunit beta protein (85-143AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. Can bind NADP (in vitro).
  • 基因功能參考文獻:
    1. Results show that MAT2B expression is frequently upregulated in malignant melanoma tissues. MAT2B downregulation delays tumor growth in vivo, and suppressed cell growth, colony formation ability and induced apoptosis in vitro indicating that MAT2B is critical for melanoma cell proliferation and tumorigenicity. PMID: 27573889
    2. Interaction between MAT2B and GIT1 serves as a scaffold and facilitates signaling in multiple steps of the Ras/Raf/MEK/ERK pathway PMID: 25794709
    3. Mutagenesis of MATalpha2 and MATbeta phospho-sites destabilized them and prevented hepatic stellate cell trans-differentiation. PMID: 25294683
    4. MAT2B and GIT1 form a scaffold, which recruits and activates MEK and ERK to promote growth and tumorigenesis. PMID: 23325601
    5. The structure of MAT2B reveals a short-chain dehydrogenase/reductase (SDR) core with specificity for the NADP/H cofactor, and harbors the SDR catalytic triad. PMID: 23425511
    6. Coexpression of MAT2A and MAT2B in COS-1 cells resulted in significantly increased MAT enzyme activity. PMID: 21813468
    7. Data show MAT2beta variants reside mostly in the nucleus and regulate HuR subcellular content to affect cell proliferation. PMID: 20421296
    8. Lower expression of both MAT2A and MAT2beta and interfere with leptin signaling in liver cancer cells. PMID: 18041713
    9. Splicing variants of MAT2beta are up-regulated in hepatocellular carcinoma and regulated tumor cell growth and death. PMID: 18045590
    10. a switch in MAT expression in liver cancer was accompanied by increasing expression of MAT2B PMID: 18698677
    11. differences in malignant cell survival, effected by MAT-IIbeta ablation, suggest that it may be possible to use this approach to disadvantage leukemic cell survival in vivo with little to no harm to normal cells. PMID: 18753136

    顯示更多

    收起更多

  • 蛋白家族:
    DTDP-4-dehydrorhamnose reductase family, MAT2B subfamily
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 6905

    OMIM: 605527

    KEGG: hsa:27430

    STRING: 9606.ENSP00000325425

    UniGene: Hs.54642



主站蜘蛛池模板: 很黄很黄的曰批视频| 日日拍夜夜嗷嗷叫|日日摸| 精品国产国语对白久久免费| 人妻丰满av无码中文字幕| 三级无码在钱av无码在钱| 人妻精品久久久久中文字幕| 伊人久久久精品区aaa片| 国产精品美女久久久久av爽李琼| 欧美国产亚洲日韩在线二区 | 在线观看片a免费不卡观看| 嫩草av久久伊人妇女超级a| 免费无码又爽又刺激高潮视频| 2020最新国产在线不卡a| 久久视热这里只有精品| 久久久国产精品无码免费专区 | 免费午夜无码片在线观看影院| 亚洲人成网站18禁止大| 五十路熟妇高熟无码视频| 天天躁日日躁很很很躁| 又色又爽又黄的gif动态图 | 国产成人三级一区二区在线观看一 | 波多野结衣aⅴ在线| 亚洲中文字幕乱码一区| 精品综合久久久久久8888| 色八区人妻在线视频| 黑人上司粗大拔不出来电影| 无码人妻一区二区三区免费n鬼逝 好爽好湿好硬好大免费视频 | 国产免费又色又爽又黄软件| 中文字幕无码无码专区| 日日躁夜夜躁狠狠躁超碰97| 麻豆精产一二三产区| 中文天堂最新版资源www官网| 久久精品国产精品亚洲毛片| 亚洲va无码专区国产乱码| 日射精情感性色视频| 又粗又大又黄又爽的免费视频| 国模无码一区二区三区| 久久综合少妇11p| 中文字幕久热精品视频在线| 无码人妻精品一区二区在线视频| 国产真实偷乱视频|