在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MAPRE3 Antibody

MAPRE3 Antibody

  • 中文名稱：
    MAPRE3兔多克隆抗體
  • 貨號：
    CSB-PA994832
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA994832(MAPRE3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA994832(MAPRE3 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human fetal brain tissue, mouse brain tissue, Primary antibody: CSB-PA994832(MAPRE3 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MAPRE3
  • 別名：
    APC binding protein antibody; EB 3 antibody; EB1 protein family member 3 antibody; EB3 antibody; EBF 3 antibody; EBF-3 antibody; EBF3 antibody; EBF3 S antibody; End binding protein 3 antibody; End-binding protein 3 antibody; MAPRE 3 antibody; MAPRE3 antibody; MARE3_HUMAN antibody; Member 3 antibody; Microtubule Associated Protein antibody; Microtubule associated protein RP/EB family member 3 antibody; Microtubule-associated protein RP/EB family member 3 antibody; OTTHUMP00000200910 antibody; RP 3 antibody; RP/EB Family antibody; RP3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human MAPRE3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. Promotes elongation of CAMSAP2-decorated microtubule stretches on the minus-end of microtubules. May play a role in cell migration.
  • 基因功能參考文獻：
    1. One candidate pathway coupling actin filaments to microtubules consists of the actin filament-binding protein drebrin and the microtubule-binding +TIP protein EB3. This pathway is regulated proximally by cyclin-dependent kinase 5 phosphorylation of drebrin but the upstream elements in the pathway have yet to be identified. PMID: 28865014
    2. Findings show that co-ordination of dynamic microtubules and actin filaments by the drebrin/EB3 pathway drives prostate cancer cell invasion and is therefore implicated in disease progression. PMID: 28319065
    3. Findings suggest that methylation-associated down-regulation of EBF3 and IRX1 genes may play an important role in a pathogenic effect of TGF-beta on RASFs. PMID: 23456299
    4. Daughter cell adhesion and cytokinesis completion are spatially regulated by distinct states of EB3 phosphorylation on serine 176 by Aurora B. PMID: 23712260
    5. decreasing the drebrin E levels disrupted the normal subapical F-actin-myosin-IIB-betaII-spectrin network and the apical accumulation of EB3, a microtubule-plus-end-binding protein PMID: 22275434
    6. VE-cadherin outside-in signaling regulates cytosolic calcium homeostasis and EB3 phosphorylation. PMID: 23159740
    7. study found a polycytosine repeat (C8) in exon 5 of MAPRE3 that could be a potential mutation target in cancers with microsatellite instability (MSI); found that the C8 is frequently mutated in gastric and colorectal carcinomas with MSI PMID: 20632835
    8. The RP3 protein is involved in SATB1-mediated gene repression of Bcl2 and dynein subunit rp3 has functions independent of the dynein motor. PMID: 16079286
    9. Data show that two mitotic kinases, Aurora-A and Aurora-B, phosphorylate endogenous EB3 at Ser-176, and the phosphorylation triggers disruption of the EB3-SIAH-1 complex, resulting in EB3 stabilization during mitosis. PMID: 19696028

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    MAPRE family
  • 組織特異性：
    Predominantly expressed in brain and muscle.
  • 數據庫鏈接：

    HGNC: 6892

    OMIM: 605788

    KEGG: hsa:22924

    STRING: 9606.ENSP00000233121

    UniGene: Hs.515860



主站蜘蛛池模板： 麻豆果冻精东九一传媒mv| 韩国理伦片一区二区三区在线播放| 亚洲人成色777777精品音频| 欧美videos另类极品| 精品亚洲卡一卡2卡三卡乱码| 欧美裸体xxxx极品| 蜜臀av色欲a片无码一区二区| 国产卡一卡二卡三无线乱码新区| 波多野结衣中文字幕久久| 无码人妻精品一区二区三区免费| 国产成年女人毛片80s网站| 亚洲成a人片在线观看无码专区| 亚洲电影在线观看| 午夜时刻免费入口| 精品系列无码一区二区三区 | 久久久综合九色综合88| 无码av在线一本无码| 免费人成小说在线观看网站 | 18禁免费观看网站| 国产女人爽的流水毛片| 无码东京热一区二区三区| 一卡二卡3卡四卡网站精品| 情人伊人久久综合亚洲| 欧美最猛黑人xxxx黑人猛交| 国产国产成人久久精品| 亚洲老熟女av一区二区在线播放 | 日本高清视频www夜色资源| 国产精品国产三级国产av麻豆| 99热这里只有是精品2| 日韩人妻一区二区三区蜜桃视频| 欧美日韩精品一区二区视频| 狠狠久久精品中文字幕无码| av片在线观看永久免费| 夜夜嗨av一区二区三区| 国产黑色丝袜在线观看下| 欧美黑人又粗又大xxx| 国产乱人伦无无码视频试看| 国产又色又爽又黄又免费软件| 日本中文字幕乱码aa高清电影| 麻豆av久久av盛宴av| 亚洲 小说区 图片区 都市|