在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MAPRE2 Antibody, HRP conjugated

  • 中文名稱:
    MAPRE2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA618987LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MAPRE2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MAPRE2
  • 別名:
    APC binding protein EB1 antibody; APC binding protein EB2 antibody; APC-binding protein EB2 antibody; EB1 antibody; EB2 antibody; End binding protein 2 antibody; End-binding protein 2 antibody; H.sapiens mRNA for novel T cell activation protein antibody; MAPRE2 antibody; MARE2_HUMAN antibody; Microtubule associated protein RP/EB family member 2 antibody; Microtubule-associated protein RP/EB family member 2 antibody; RP1 antibody; T cell activation protein EB1 family antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Microtubule-associated protein RP/EB family member 2 protein (159-240AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
  • 基因功能參考文獻:
    1. Aurora B and CDK1 temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability. PMID: 27030108
    2. Mutations in either TUBB or MAPRE2 cause circumferential skin creases Kunze type. PMID: 26637975
    3. EB2 is evidently important for initial microtubule reorganisation during epithelial polarisation, whereas its downregulation facilitates EB1 and ACF7 microtubule lattice association, microtubule-actin filament co-alignment and bundle formation. PMID: 23813963
    4. results suggest that EB1 and ClipCG12 act cooperatively to regulate microtubule dynamics (EB1) PMID: 22424550
    5. heterodimer formation between EB1 and EB3, but not between EB2 and the other two EBs, occurs both in vitro and in cells as revealed by live cell imaging PMID: 20008324
    6. Data suggest that a functional interaction between EB1 and p150(Glued) is required for microtubule minus end anchoring at centrosomes during the assembly and maintenance of a radial microtubule array. PMID: 12388762
    7. EB1 may modulate kinetochore microtubule polymerization and/or attachment PMID: 12475954
    8. results support the novel hypothesis that EB1 overexpression may play a role in the development of esophageal squamous cell carcinoma by affecting APC function and activating the beta-catenin/TCF pathway PMID: 16007168
    9. Impaired EB1 or APC function generates lesions invisible to the spindle checkpoint and thereby promotes low levels of chromosomal loss (CIN) expected to fuel aneuploidy and possibly tumorigenesis. PMID: 16763565
    10. These data demonstrate that the COP9 signalosome-dependent protection of EB1 is important for microtubule function. PMID: 17350042
    11. Crystal structures of the tubulin binding domains of XMAP215 (yeast Stu2p and Drosophila Msps), EB1 (yeast Bim1p and human EB1), and CLIP-170 (human), which reveal diverse tubulin binding interfaces, are reported. PMID: 17889670
    12. p150Glued may activate and thereby facilitate the recruitment of EB1 to the tips of microtubules to regulate their dynamics. PMID: 18081319
    13. EB1-tubulin interactions are mediated in part by the same tubulin acidic tails utilized by other MAPs PMID: 19778897
    14. MAPRE2 is highly expressed in pancreatic cancer cells, and seems to be involved in perineural invasion PMID: 19787265

    顯示更多

    收起更多

  • 相關疾病:
    Skin creases, congenital symmetric circumferential, 2 (CSCSC2)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules.
  • 蛋白家族:
    MAPRE family
  • 組織特異性:
    Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
  • 數據庫鏈接:

    HGNC: 6891

    OMIM: 605789

    KEGG: hsa:10982

    STRING: 9606.ENSP00000300249

    UniGene: Hs.532824



主站蜘蛛池模板: 亚洲欧美人成网站aaa| 人妻少妇乱子伦精品无码专区电影| 97久久超碰国产精品旧版麻豆| 早起邻居人妻奶罩太松av| 成人国产亚洲精品a区天堂| 中国精品少妇hd| 欧美亚洲国产精品久久蜜芽| 亚洲中文字幕av每天更新| 久久一卡二卡三卡四卡| 精品无人码麻豆乱码1区2区 | 蜜桃网站入口在线进入| 精品国产免费一区二区三区香蕉| 亚洲第一无码专区天堂| 久久99亚洲精品久久久久| 日本精品aⅴ一区二区三区| 国产精品偷窥熟女精品视频| 国产乱妇无乱码大黄aa片| 纯肉无遮挡无码日本动漫| 人人妻人人澡人人爽偷拍台湾| 特黄做受又粗又大又硬老头| 看免费真人视频网站| 国产精品成人a区在线观看| 99视频有精品视频高清| 免费1级做爰片在线观看爱| 久久精品午夜福利| 丰满诱人的人妻3| 捆绑白丝粉色jk震动捧喷白浆| 伊人久久大香线蕉影院| 国产成年无码久久久久下载 | 女人被狂c躁到高潮视频| 国产私拍大尺度在线视频| 色欲久久综合亚洲精品蜜桃| 午夜一区二区亚洲福利| 日本饥渴人妻欲求不满| 亚洲成色在线综合网站| 亚洲欧洲精品a片久久99| 国产精品久久久久久不卡盗摄 | 少妇富婆高级按摩出水高潮| 日本高清在线一区二区三区 | 精品国模一区二区三区| 亚洲人精品午夜射精日韩|