在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

MAPRE2 Antibody, Biotin conjugated

  • 中文名稱:
    MAPRE2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA618987LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MAPRE2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MAPRE2
  • 別名:
    APC binding protein EB1 antibody; APC binding protein EB2 antibody; APC-binding protein EB2 antibody; EB1 antibody; EB2 antibody; End binding protein 2 antibody; End-binding protein 2 antibody; H.sapiens mRNA for novel T cell activation protein antibody; MAPRE2 antibody; MARE2_HUMAN antibody; Microtubule associated protein RP/EB family member 2 antibody; Microtubule-associated protein RP/EB family member 2 antibody; RP1 antibody; T cell activation protein EB1 family antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Microtubule-associated protein RP/EB family member 2 protein (159-240AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
  • 基因功能參考文獻:
    1. Aurora B and CDK1 temporally regulate the binding affinity of EB2 for microtubules, thereby ensuring kinetochore microtubule dynamics, proper mitotic progression and genome stability. PMID: 27030108
    2. Mutations in either TUBB or MAPRE2 cause circumferential skin creases Kunze type. PMID: 26637975
    3. EB2 is evidently important for initial microtubule reorganisation during epithelial polarisation, whereas its downregulation facilitates EB1 and ACF7 microtubule lattice association, microtubule-actin filament co-alignment and bundle formation. PMID: 23813963
    4. results suggest that EB1 and ClipCG12 act cooperatively to regulate microtubule dynamics (EB1) PMID: 22424550
    5. heterodimer formation between EB1 and EB3, but not between EB2 and the other two EBs, occurs both in vitro and in cells as revealed by live cell imaging PMID: 20008324
    6. Data suggest that a functional interaction between EB1 and p150(Glued) is required for microtubule minus end anchoring at centrosomes during the assembly and maintenance of a radial microtubule array. PMID: 12388762
    7. EB1 may modulate kinetochore microtubule polymerization and/or attachment PMID: 12475954
    8. results support the novel hypothesis that EB1 overexpression may play a role in the development of esophageal squamous cell carcinoma by affecting APC function and activating the beta-catenin/TCF pathway PMID: 16007168
    9. Impaired EB1 or APC function generates lesions invisible to the spindle checkpoint and thereby promotes low levels of chromosomal loss (CIN) expected to fuel aneuploidy and possibly tumorigenesis. PMID: 16763565
    10. These data demonstrate that the COP9 signalosome-dependent protection of EB1 is important for microtubule function. PMID: 17350042
    11. Crystal structures of the tubulin binding domains of XMAP215 (yeast Stu2p and Drosophila Msps), EB1 (yeast Bim1p and human EB1), and CLIP-170 (human), which reveal diverse tubulin binding interfaces, are reported. PMID: 17889670
    12. p150Glued may activate and thereby facilitate the recruitment of EB1 to the tips of microtubules to regulate their dynamics. PMID: 18081319
    13. EB1-tubulin interactions are mediated in part by the same tubulin acidic tails utilized by other MAPs PMID: 19778897
    14. MAPRE2 is highly expressed in pancreatic cancer cells, and seems to be involved in perineural invasion PMID: 19787265

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Skin creases, congenital symmetric circumferential, 2 (CSCSC2)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton. Note=Associated with the microtubule network. Accumulates at the plus end of microtubules.
  • 蛋白家族:
    MAPRE family
  • 組織特異性:
    Expressed in different tumor cell lines. Up-regulated in activated B- and T-lymphocytes.
  • 數據庫鏈接:

    HGNC: 6891

    OMIM: 605789

    KEGG: hsa:10982

    STRING: 9606.ENSP00000300249

    UniGene: Hs.532824



主站蜘蛛池模板: 色窝窝免费一区二区三区| 国产精品亚洲a∨天堂| 亚洲熟妇丰满大屁股熟妇| 少妇扒开粉嫩小泬视频| 久久久亚洲色| 99精品国产丝袜在线拍国语| 男男又爽又黄又无遮挡网站| 国产偷亚洲偷欧美偷精品| 国内自产少妇自拍区免费| 国产成人精品久久一区二区| 国产亚洲精品a片久久久| 内射后入在线观看一区| 亚洲乱码国产乱码精品精大量| 欧美日韩亚洲tv不卡久久| 精品人成视频免费国产| 大又大粗又爽又黄少妇毛片| 日韩av无码久久一区二区| 首页 国产 亚洲 丝袜图片区| 久久av高潮av无码av喷吹| 久久五月精品中文字幕| 精品无码欧美黑人又粗又| 国产欧美日韩精品专区| 国产又大又硬又粗| 国产免费一区二区三区免费视频| 日本欧美一区二区三区在线播放| 鲁鲁网亚洲站内射污| 国精产品一二三区精华液| 久久国产美女精品久久| 人妻性奴波多野结衣无码| 亚洲丰满熟女一区二区v| 双腿张开被9个男人调教| 秋霞无码久久久精品交换| 日本高清视频wwww色| 国产乱人伦在线播放| 亚洲欧美另类成人综合图片| 欧美人与动性xxxxx交性| 黑人玩弄出轨人妻松雪| 成在人线av无码免费高潮水老板| 国自产拍偷拍精品啪啪av| 久久国产福利国产秒拍| 久久午夜无码鲁丝片秋霞|