在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MAP3K9 Antibody, Biotin conjugated

MAP3K9 Antibody, Biotin conjugated

  • 中文名稱：
    MAP3K9兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA013434LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MAP3K9 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MAP3K9
  • 別名：
    M3K9_HUMAN antibody; Map3k9 antibody; MEKK9 antibody; Mitogen activated protein kinase kinase kinase 9 antibody; Mitogen-activated protein kinase kinase kinase 9 antibody; Mixed lineage kinase 1 (tyr and ser/thr specificity) antibody; Mixed lineage kinase 1 antibody; MLK1 antibody; PRKE1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Mitogen-activated protein kinase kinase kinase 9 protein (864-1098AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.
  • 基因功能參考文獻：
    1. Data report that MKL1 was both sufficient and necessary for p65-dependent pro-inflammatory transcriptional program. MKL1 deficiency erased key histone modifications synonymous with transactivation on p65 target promoters. Specifically, MKL1 defined histone H3K4 trimethylation landscape for NF-kappaB dependent transcription. PMID: 28298643
    2. There was a negatively relationship between miR-15a and MAP3K9 expression in NP cells. PMID: 28081468
    3. miR148b directly targeted mitogenactivated protein kinase (MAPK) kinase kinase 9 (MAP3K9), an upstream activator of MAPK kinase/cJun Nterminal kinase (JNK) signaling, suppressing the protein but not the mRNA levels. PMID: 26573018
    4. identified three kinases with gain-of-function mutations in lung cancer, namely FGFR4, MAP3K9, and PAK5. Mutations in these kinases are activating toward the ERK pathway, and targeted depletion of the mutated kinases inhibits proliferation PMID: 23836671
    5. estrogen receptor-alpha transcriptional activity is repressed by the Rho/megakaryoblastic leukemia 1 signaling pathway PMID: 19826002

    顯示更多

    收起更多

  • 相關疾?。?/div>
    May play a role in esophageal cancer susceptibility and/or development.
  • 蛋白家族：
    Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
  • 組織特異性：
    Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.
  • 數據庫鏈接：

    HGNC: 6861

    OMIM: 600136

    KEGG: hsa:4293

    STRING: 9606.ENSP00000451263

    UniGene: Hs.445496



主站蜘蛛池模板： 国产成人精品永久免费视频| 欧美午夜成人片在线观看| 国产精品门事件av| 一二三四在线观看视频韩国| 精品无人国产偷自产在线 | 1000部精品久久久久久久久| 中文天堂在线www最新版官网| 99re8精品视频热线观看| 国产三级aⅴ在在线观看| 午夜羞羞影院男女爽爽爽| av色欲无码人妻中文字幕| 亚洲影院天堂中文av色| 国产精品乱子伦xxxx| 上海少妇高潮狂叫喷水了| 国产成人av综合色| 免费人成在线观看视频播放| 色情久久久av熟女人妻网站| 国产成人无码精品一区二区三区| 五 月 丁 香 综合中文| 国产一码二码三码区别| 国产美女在线精品免费观看| 亚洲小说图区综合在线| 中文字幕有码无码人妻在线| 日日摸日日碰夜夜爽亚洲 | 亚洲精品成人老司机影视| 无码专区亚洲制服丝袜| 制服丝袜另类专区制服| 92久久精品一区二区| 日韩国产高清一区二区| 伊人狼人大焦香久久网| 人禽伦免费交视频播放| 女的被弄到高潮娇喘喷水视频| 一区二区视频传媒有限公司| 欧美不卡视频一区发布| 久久久久久av无码免费看大片| 久久久久99人妻一区二区三区| 国产无套粉嫩白浆在线| 亚洲精品无码专区在线| 性动态图av无码专区| 酒店大战丝袜高跟鞋人妻| 久国产精品人妻aⅴ|