在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MAP1B Antibody

MAP1B Antibody

  • 中文名稱：
    MAP1B兔多克隆抗體
  • 貨號：
    CSB-PA218026
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA218026(MAP1B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA218026(MAP1B Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    MAP1B
  • 別名：
    FUTSCH antibody; LC1 antibody; MAP-1B antibody; MAP1 light chain LC1 antibody; Map1b antibody; MAP1B_HUMAN antibody; MAP5 antibody; Microtubule associated protein 1B antibody; Mtap1b antibody; Mtap5 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human MAP1B
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:3000-1:10000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Facilitates tyrosination of alpha-tubulin in neuronal microtubules. Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.
  • 基因功能參考文獻：
    1. All of the patients with a microtubule associated protein 1B (MAP1B) variant had a similar brain abnormality, and at least one of the parents who transmitted the variant to their child was also similarly affected. PMID: 29738522
    2. MAP1B heavy chain has a unique binding site for a calcium-binding protein ALG-2. PMID: 29432744
    3. These results suggest that a change in the intracellular calcium level plays a role in regulation of the secretory pathway via interaction of ALG-2 with MISSL and MAP1B. PMID: 28864773
    4. The found of this study suggested that possible roles of MAP1B genes in working memory performance in ADHD patients PMID: 26233433
    5. KIRREL3 interacting proteins MAP1B and MYO16 are potential candidates for intellectual disability and autism spectrum disorder. PMID: 25902260
    6. signal transduction pathways downstream of 5-HT6R are regulated by MAP1B, which might play a role in 5-HT6R-mediated signaling in the brain. PMID: 24614691
    7. The the MAP1B-LC1-mediated regulation most likely involves an internalization of the channels via a dynamin and clathrin-dependent pathway. PMID: 25483588
    8. An interaction between MAP1B LC1 and the ubiquitin-conjugating enzyme UBE2L3. PMID: 24566975
    9. Localization of MAP1B is altered in amyotrophic lateral sclerosis spinal cords in a transgenic animal model. PMID: 25429138
    10. Yeast-two-hybrid screening using human LRRK2 kinase domain as bait identified microtubule associated protein 1B (MAP1B) as a LRRK2 interactor. PMID: 24754922
    11. We suggest a role for Stau2 in the generation and regulation of Map1b mRNA containing granules that are required for mGluR-long-term depression PMID: 21508097
    12. These observations define a new and crucial function of MAP1B that is required for efficient cross-talk between microtubules and the actin cytoskeleton during neuronal polarization. PMID: 20719958
    13. MAP1B action is modulated by mapmodulin/leucine-rich acidic nuclear protein PMID: 12807913
    14. The light chain (LC1) of microtubule-associated protein 1B (MAP1B)-5-HT(3A) receptor interaction contributes to a mechanism that regulates receptor desensitization kinetics. PMID: 18063656
    15. Amyloid-beta 1-42 binds to a peptide comprising the microtubule binding domain of the heavy chain of microtubule-associated protein 1B by the screening of a human brain cDNA library expressed on M13 phage. PMID: 18079022
    16. a role for MAP1B in DAPK-1-dependent signaling in autophagy and membrane blebbing. PMID: 18195017
    17. MAP1B light chain can interact with the tumor suppressor p53. PMID: 18656471
    18. a new protein involved in the terminal differentiation of odontoblasts PMID: 19567321

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm. Cell junction, synapse. Cell projection, dendritic spine.; [MAP1 light chain LC1]: Cytoplasm.
  • 蛋白家族：
    MAP1 family
  • 數據庫鏈接：

    HGNC: 6836

    OMIM: 157129

    KEGG: hsa:4131

    STRING: 9606.ENSP00000296755

    UniGene: Hs.335079



主站蜘蛛池模板： 亚洲精品无码久久久| 欧洲精品一卡2卡三卡4卡影视 | 欧美日韩人人模人人爽人人喊| 在线视频 亚太 国产 欧美 一区二区 | 无码国内精品久久人妻蜜桃| 国产精品天干在线观看| 国产欧美日韩一区二区三区| 日本极品少妇xxxx| 日本www一道久久久免费| 久久理论片午夜琪琪电影网 | 亚洲成av人片在线观看橙子| 亚洲男人天堂| 精品乱码一区二区三区四区| 国产一卡三卡四卡无卡精品 | 96亚洲精华国产精华精华液| 人妻少妇精品无码专区动漫| 狠狠干狠狠爱| 久久综合a∨色老头免费观看| 怡红院一区二区三区在线| www污污污抽搐喷潮com| 成人影片一区免费观看| 中文字幕第一区高清av| 中字幕久久久人妻熟女天美传媒 | 亚洲欧美中文字幕日韩一区二区| 影音先锋中文字幕人妻| 无遮挡国产高潮视频免费观看| 又粗又紧又湿又爽的视频| 天天天天躁天天爱天天碰| 风间由美性色一区二区三区| 亚洲国产精品无码专区| 日韩免费人妻av无码专区蜜桃| 大胸美女被吃奶爽死视频| 亚洲中文字幕无码一区在线| 欧美肥婆性猛交xxxx| 好想被狂躁无码视频在线观看| 国产精品久线在线观看| 成人无码视频在线观看大全| 午夜成人性刺激免费视频| 久久av高清无码| 欧美 国产日韩 综合在线| 欧美成人天天综合在线|