在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. MAEL Antibody, HRP conjugated

MAEL Antibody, HRP conjugated

  • 中文名稱：
    MAEL兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA842695LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MAEL Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MAEL
  • 別名：
    cancer/testis antigen 128 antibody; CT128 antibody; FLJ14904 antibody; mael antibody; MAEL_HUMAN antibody; maelstrom homolog (Drosophila) antibody; Maelstrom homolog antibody; OTTHUMP00000032344 antibody; Protein maelstrom homolog antibody; RP11-102C16.1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein maelstrom homolog protein (1-200AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.
  • 基因功能參考文獻(xiàn)：
    1. MAEL promoter hypermethylation may have a role in de-repression of LINE-1 in human hypospermatogenesis PMID: 29095993
    2. Report found that Mael is activated in proliferating cancer cells, where it serves to maintain genetic stability. Its depletion results in an increase in reactive oxygen species, followed by apoptosis or senescence. PMID: 27926513
    3. Data suggest that overexpression of MAEL, caused by gene amplification and/or decreased miR-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1. PMID: 27181205
    4. Study demonstrated that MAEL interacts with Snail and inhibit E-cadherin promoter activity. MAEL is an oncogene that plays an important role in the development and progression of colon cancer. PMID: 27537253
    5. Immunofluorescence analysis showed that MAEL co-localizes with the stress granule marker PABPC1 in stress granules during oxidative stress. MAEL may be involved in miRNA-mediated gene silencing in SGs. PMID: 24189637
    6. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt/GSK-3beta/Snail signaling. PMID: 23929794
    7. These results suggest that MAEL is a novel cancer/testis-associated gene and is regulated by DNA methylation. PMID: 19693694

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Maelstrom family
  • 組織特異性：
    Testis-specific. Expressed in various cancer cell lines, probably due to demethylation of its promoter.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25929

    OMIM: 611368

    KEGG: hsa:84944

    STRING: 9606.ENSP00000356846

    UniGene: Hs.651245



主站蜘蛛池模板： 高潮毛片又色又爽免费| 中文字幕大看蕉在线观看| 国产精品一区二区 尿失禁| 人妻少妇中文字幕乱码| 精品www日韩熟女人妻| 国产素人在线观看人成视频 | 无码中文av有码中文av| 久久综合九色综合欧美就去吻 | 粉嫩极品国产在线观看| 国产精品欧美亚洲韩国日本久久| 人人妻人人澡人人爽欧美一区九九| 无套内谢少妇毛片aaaa片免费 | 精品久久久久久久久午夜福利| 又色又爽又黄的美女裸体网站| 国产精品va无码免费| 女人与拘性猛交视频| 亚洲日本va午夜中文字幕久久| 国产成人a在线观看视频| 99精品众筹模特自拍视频| 亚洲伊人色欲综合网| 色欲天天婬色婬香综合网完整版| 亚洲精品aa片在线观看国产| 亚洲自偷精品视频自拍| 香蕉久久一区二区三区啪啪| 久久99亚洲含羞草影院| 中文字幕丝袜第1页| 午夜精品久久久久久久无码| 漂亮人妻熟睡中被公侵犯中文版| 国产精品无码久久综合网| 日本少妇春药特殊按摩3| 天堂资源在线www中文| 色欲天天网站欧美成人福利网| 免费无码又爽又刺激毛片| 国产熟妇另类久久久久| 国产成人无码精品久久久免费| 欧美激烈精交gif动态图| 国产偷窥熟女高潮精品视频| 日韩精品区一区二区三vr| 美女黄频视频大全免费的国内| 一区二区三区无码免费看| 亚洲精品乱码久久久久久蜜桃图片|