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MAB21L2 Antibody, HRP conjugated

  • 中文名稱:
    MAB21L2兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA896901LB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MAB21L2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MAB21L2
  • 別名:
    MAB21L2 antibody; Protein mab-21-like 2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein mab-21-like 2 protein (1-300AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for several aspects of embryonic development including normal development of the eye.
  • 基因功能參考文獻:
    1. mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review] PMID: 27558071
    2. The two unrelated individuals with a novel oculo-skeletal syndrome with intellectual disability described are heterozygous carriers of the same de novo missense mutation c.151C > T (p.Arg51Cys) in MAB21L2. PMID: 26116559
    3. These findings support the identification of MAB21L2 as a novel factor involved in human coloboma and highlight the power of genome editing manipulation in model organisms for analysis of the effects of whole exome variation in humans. PMID: 25719200
    4. This report provides compelling human genomic and genetic evidence that mutations in MAB21L2 cause major eye malformations. PMID: 24906020
  • 相關疾病:
    Microphthalmia/coloboma and skeletal dysplasia syndrome (MCSKS)
  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Mab-21 family
  • 數據庫鏈接:

    HGNC: 6758

    OMIM: 604357

    KEGG: hsa:10586

    STRING: 9606.ENSP00000324701

    UniGene: Hs.584852



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