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MAB21L1 Antibody, FITC conjugated

  • 中文名稱:
    MAB21L1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA623800LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) MAB21L1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    MAB21L1
  • 別名:
    MAB21L1 antibody; CAGR1 antibody; Nbla00126Putative nucleotidyltransferase MAB21L1 antibody; EC 2.7.7.- antibody; Protein mab-21-like 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Putative nucleotidyltransferase MAB21L1 protein (1-359AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye. It is unclear whether it displays nucleotidyltransferase activity in vivo. Binds single-stranded RNA (ssRNA).
  • 基因功能參考文獻:
    1. Mab21l1-/- osteoblasts also expressed higher levels of adipocyte genes and interferon-regulated genes at early stages of osteogenesis PMID: 29156428
    2. offer a structure-based explanation for the effects of MAB21L2 mutations in patients with eye malformations PMID: 27271801
    3. mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review] PMID: 27558071
    4. We hypothesize that MAB21L1 haploinsufficiency cause a previously undescribed syndrome with scrotal agenesis, ophthalmological anomalies, facial dysmorphism and gross psychomotor delay as remarkable hallmarks. PMID: 27103078
    5. MEF is involved in PTH suppression of osteoblasts through activating the MKK4/JNK1 pathway and subsequently up-regulating Mab21l1 expression. PMID: 21465527

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  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Mab-21 family
  • 組織特異性:
    Expressed in brain, cerebellum and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 6757

    OMIM: 601280

    KEGG: hsa:4081

    STRING: 9606.ENSP00000369251

    UniGene: Hs.584776



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