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  4. MAB21L1 Antibody, Biotin conjugated

MAB21L1 Antibody, Biotin conjugated

  • 中文名稱：
    MAB21L1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA623800LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) MAB21L1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    MAB21L1
  • 別名：
    MAB21L1 antibody; CAGR1 antibody; Nbla00126Putative nucleotidyltransferase MAB21L1 antibody; EC 2.7.7.- antibody; Protein mab-21-like 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Putative nucleotidyltransferase MAB21L1 protein (1-359AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye. It is unclear whether it displays nucleotidyltransferase activity in vivo. Binds single-stranded RNA (ssRNA).
  • 基因功能參考文獻：
    1. Mab21l1-/- osteoblasts also expressed higher levels of adipocyte genes and interferon-regulated genes at early stages of osteogenesis PMID: 29156428
    2. offer a structure-based explanation for the effects of MAB21L2 mutations in patients with eye malformations PMID: 27271801
    3. mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. [review] PMID: 27558071
    4. We hypothesize that MAB21L1 haploinsufficiency cause a previously undescribed syndrome with scrotal agenesis, ophthalmological anomalies, facial dysmorphism and gross psychomotor delay as remarkable hallmarks. PMID: 27103078
    5. MEF is involved in PTH suppression of osteoblasts through activating the MKK4/JNK1 pathway and subsequently up-regulating Mab21l1 expression. PMID: 21465527

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  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Mab-21 family
  • 組織特異性：
    Expressed in brain, cerebellum and skeletal muscle.
  • 數據庫鏈接：

    HGNC: 6757

    OMIM: 601280

    KEGG: hsa:4081

    STRING: 9606.ENSP00000369251

    UniGene: Hs.584776



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