在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

LLGL2 Antibody

  • 中文名稱:
    LLGL2兔多克隆抗體
  • 貨號:
    CSB-PA889962
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA889962(LLGL2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    HGL antibody; Human giant larvae homolog antibody; L2GL2 antibody; L2GL2_HUMAN antibody; Lethal 2 giant larvae protein homolog 2 antibody; Lethal giant larvae homolog 2 antibody; Lethal(2) giant larvae protein homolog 2 antibody; LGL2 antibody; LLGL2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthetic peptide of Human LLGL2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
  • 基因功能參考文獻:
    1. The crystal structures of the Dlg4 GK domain in complex with two phosphor-Lgl2 peptides reveal the molecular mechanism underlying the specific and phosphorylation-dependent Dlg/Lgl complex formation. PMID: 24513855
    2. It is correlated with lymphatic invasion and lymph node metastasis. PMID: 24318287
    3. Loss or aberrant Lgl2 staining was useful in identifying Barrett gastric foveolar dysplasia PMID: 23332925
    4. Hugl-2 induces MET and suppresses Snail tumorigenesis. PMID: 22580609
    5. Hugl1 and Hugl2 play an essential role in the maintenance of breast epithelial polarity and differentiated cell morphology, as well as growth control. PMID: 23110097
    6. There is a role of Lgl2 immunohistochemistry as an adjunct in the diagnosis of foveolar-type gastric dysplasia. PMID: 20941506
    7. Lgl2 differentiates pancreatic intraepithelial neoplasia-3 and ductal adenocarcinoma of the pancreas from lower-grade pancreatic intraepithelial neoplasias. PMID: 20233622
    8. binding between Lgl2 and LGN play a role in mitotic spindle organization through regulating formation of the LGN.NuMA complex; Lgl2 forms a Lgl2.Par-6.aPKC.LGN complex, which responds to mitotic signaling to establish normal cell division PMID: 15632202
    9. The identification and functional characterization of the promoter region ( approximately 1.2kb) of the Hugl-2 gene are reported. PMID: 18155665
    10. Retention of Lgl2 expression is critical for the epithelial phenotype;its loss might be involved in metastasis. PMID: 18199550
    11. We propose that Lgl2 may be a potential marker to rule out gastric epithelial dysplasia and adenocarcinoma in diagnostic specimens. PMID: 19407852

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.
  • 蛋白家族:
    WD repeat L(2)GL family
  • 數據庫鏈接:

    HGNC: 6629

    KEGG: hsa:3993

    STRING: 9606.ENSP00000376333

    UniGene: Hs.514477



主站蜘蛛池模板: 把女邻居弄到潮喷的性经历| 少妇做爰免费视频了| 强开小婷嫩苞又嫩又紧视频| 娇妻被黑人粗大高潮白浆| 免费人成网站在线观看欧美| 三级做a全过程在线观看| 99国产成人精品视频| 四虎成人国产精品永久在线| 亚洲人成人网站在线观看| av无码精品一区二区三区| 狠狠干狠狠爱| 午夜无码性爽快影院6080| 国产精品极品在线拍| 色综合久久网| 欧美人与动牲交a欧美精品| 大陆熟妇丰满多毛xxxⅹ| 亚拍精品一区二区三区探花| 午夜高清国产拍精品| 国产精品久久久久久久久久| 国产成人艳妇aa视频在线| 国内精品久久久久久影院| 黄网站色视频免费观看| 日韩不卡1卡2卡三卡网站| 毛片免费视频观看| 中文字幕无码中文字幕有码| 日韩去日本高清在线| 无码被窝影院午夜看片爽爽jk | 亚洲va中文字幕无码久久| 国产在线不卡人成视频| 国产精品成人午夜久久| 亚洲精品高清无码视频| 成人免费看吃奶视频网站| 无码h黄肉动漫在线观看| 2019一級特黃色毛片免費看| 青青久在线视频免费观看| 成人麻豆日韩在无码视频| 亚洲国产精品无码7777一线| 国产成人三级在线视频网站观看| 水蜜桃色314在线观看| 日本免费人成视频播放| 亚洲色欲色欲天天天www|