在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LLGL2 Antibody

LLGL2 Antibody

  • 中文名稱：
    LLGL2兔多克隆抗體
  • 貨號：
    CSB-PA889962
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA889962(LLGL2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    HGL antibody; Human giant larvae homolog antibody; L2GL2 antibody; L2GL2_HUMAN antibody; Lethal 2 giant larvae protein homolog 2 antibody; Lethal giant larvae homolog 2 antibody; Lethal(2) giant larvae protein homolog 2 antibody; LGL2 antibody; LLGL2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human LLGL2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division. This complex plays roles in the initial phase of the establishment of epithelial cell polarity.
  • 基因功能參考文獻：
    1. The crystal structures of the Dlg4 GK domain in complex with two phosphor-Lgl2 peptides reveal the molecular mechanism underlying the specific and phosphorylation-dependent Dlg/Lgl complex formation. PMID: 24513855
    2. It is correlated with lymphatic invasion and lymph node metastasis. PMID: 24318287
    3. Loss or aberrant Lgl2 staining was useful in identifying Barrett gastric foveolar dysplasia PMID: 23332925
    4. Hugl-2 induces MET and suppresses Snail tumorigenesis. PMID: 22580609
    5. Hugl1 and Hugl2 play an essential role in the maintenance of breast epithelial polarity and differentiated cell morphology, as well as growth control. PMID: 23110097
    6. There is a role of Lgl2 immunohistochemistry as an adjunct in the diagnosis of foveolar-type gastric dysplasia. PMID: 20941506
    7. Lgl2 differentiates pancreatic intraepithelial neoplasia-3 and ductal adenocarcinoma of the pancreas from lower-grade pancreatic intraepithelial neoplasias. PMID: 20233622
    8. binding between Lgl2 and LGN play a role in mitotic spindle organization through regulating formation of the LGN.NuMA complex; Lgl2 forms a Lgl2.Par-6.aPKC.LGN complex, which responds to mitotic signaling to establish normal cell division PMID: 15632202
    9. The identification and functional characterization of the promoter region ( approximately 1.2kb) of the Hugl-2 gene are reported. PMID: 18155665
    10. Retention of Lgl2 expression is critical for the epithelial phenotype;its loss might be involved in metastasis. PMID: 18199550
    11. We propose that Lgl2 may be a potential marker to rule out gastric epithelial dysplasia and adenocarcinoma in diagnostic specimens. PMID: 19407852

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells. Found in the lateral region of polarized epithelial cells.
  • 蛋白家族：
    WD repeat L(2)GL family
  • 數據庫鏈接：

    HGNC: 6629

    KEGG: hsa:3993

    STRING: 9606.ENSP00000376333

    UniGene: Hs.514477



主站蜘蛛池模板： 久久国产精品福利一区二区三区| 国产高清在线精品一区免费| 国产精品久久久久久av| 无码人妻精品一区二区蜜桃百度 | 国产亚洲美女精品久久久| 亚洲va在线va天堂xx xx| 美女扒开腿让男人桶爽app免费看| 精品国产一区二区三区久久久狼| 性欧美高清come| 久久精品国产99国产精2020丨 | 中文字幕高清免费日韩视频在线| 无码国产乱人伦偷精品视频| 欧美精品成人v高清视频| 巨爆乳中文字幕巨爆区巨爆乳无码| 午夜在线观看免费线无码视频| 日本特黄特色特爽大片| 美女视频黄的全免费视频网站| 亚洲一卡2卡3卡4卡5卡乱码观看| 亚洲欧美成人一区二区三区| 国产精品igao视频网| 国产黄网永久免费视频大全| 亚洲综合天堂一区二区三区| 久久久久成人片免费观看蜜芽| 日本一卡二卡不卡视频查询| 老熟妇乱子交视频一区| 人澡人人澡人人澡欧美| 欧洲熟妇精品视频| 无人区码一码二码w358cc| 色偷偷人人澡久久超碰97| 在线观看国产精品普通话对白精品| 4hu四虎永久免费地址ww416| 后进式无遮挡啪啪摇乳动态图| 精品综合久久久久久97| 丰满人妻被黑人猛烈进入| 国产成人无码精品久久久免费| 激情97综合亚洲色婷婷五| 国产交换配乱婬视频| 一本色道久久88综合日韩精品| 满春阁精品a∨在线观看| 欧美另类精品xxxx| 精品久久久久久中文字幕|