在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LGR6 Antibody

LGR6 Antibody

  • 中文名稱(chēng)：
    LGR6兔多克隆抗體
  • 貨號(hào)：
    CSB-PA003149
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HuvEc cells using LGR6 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ14471 antibody; Gonadotropin receptor antibody; GPCR antibody; Leucine rich repeat containing G protein coupled receptor 6 antibody; Leucine-rich repeat-containing G-protein coupled receptor 6 antibody; Lgr6 antibody; LGR6_HUMAN antibody; VTS20631 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human LGR6.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
  • 基因功能參考文獻(xiàn)：
    1. Inhibition of LGR6 promoted the osteogenic differentiation of bone marrow stromal cells in vitro. PMID: 29625528
    2. Lgr6 has a tumorpromoting role in the development of colorectal cancer. PMID: 29693156
    3. Lgr6 marks mammary gland progenitor cells that can initiate tumours, and cells of luminal breast tumours required for efficient tumour maintenance. PMID: 27798604
    4. Two of the three monoclonal antibodies recognized the large N-terminal extracellular domain of leucine rich repeat containing G protein-coupled receptor 6 (LGR6), and competitively blocked the binding of R-spondin 1, which is known to be the ligand for LGR6. PMID: 28013222
    5. LGR6 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    6. Overexpression of wild-type LGR6 in HeLa cells leads to increased cell migration. PMID: 22615920

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 19719

    OMIM: 606653

    KEGG: hsa:59352

    STRING: 9606.ENSP00000356247

    UniGene: Hs.497402



主站蜘蛛池模板： 制服视频在线一区二区| 人妻丰满熟妇aⅴ无码| 风流老熟女一区二区三区| 国产激情无码视频在线播放| 色欲天天天无码视频| 午夜一区一品日本| 97香蕉碰碰人妻国产欧美| 亚洲精品无码久久久久久| 乱人伦中文视频在线| 国产清纯在线一区二区www| 国产一卡2卡3卡四卡精品app| 人妻体内射精一区二区三四| 国产精品99久久久精品无码| 成人试看30分钟免费视频 | 国产午夜精品久久久久免费视| 国产成人精品一区二区在线小狼| 久久国产精品福利一区二区三区| 国产有奶水哺乳期无码avav| 欧美精品亚洲精品日韩专区| 狠狠躁夜夜躁人人躁婷婷视频| 国产69精品久久久久久久| 人妻丝袜av先锋影音先| 激情文学小说区另类小说同性| 国产做a爰片久久毛片a片| 3d动漫精品啪啪一区二区| 国产女人喷潮视频免费| 精品综合久久久久久97| 欧美丰满熟妇bbb久久久| 天天av天天爽无码中文| 国产制服丝袜亚洲高清| 日韩精品成人av在线观看| 99久久精品无码一区二区三区| 四虎一区二区成人免费影院网址| 女人摸下面自熨视频在线播放| 国产无遮挡又黄又爽在线观看| 欧美巨鞭大战丰满少妇| 国产精品尹人在线观看| 黑人大战日本人妻嗷嗷叫不卡视频| 风间由美性色一区二区三区| 丰满人妻一区二区三区无码av| 99国产成人精品视频|