在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LGR6 Antibody

LGR6 Antibody

  • 中文名稱(chēng)：
    LGR6兔多克隆抗體
  • 貨號(hào)：
    CSB-PA003149
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HuvEc cells using LGR6 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ14471 antibody; Gonadotropin receptor antibody; GPCR antibody; Leucine rich repeat containing G protein coupled receptor 6 antibody; Leucine-rich repeat-containing G-protein coupled receptor 6 antibody; Lgr6 antibody; LGR6_HUMAN antibody; VTS20631 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human LGR6.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
  • 基因功能參考文獻(xiàn)：
    1. Inhibition of LGR6 promoted the osteogenic differentiation of bone marrow stromal cells in vitro. PMID: 29625528
    2. Lgr6 has a tumorpromoting role in the development of colorectal cancer. PMID: 29693156
    3. Lgr6 marks mammary gland progenitor cells that can initiate tumours, and cells of luminal breast tumours required for efficient tumour maintenance. PMID: 27798604
    4. Two of the three monoclonal antibodies recognized the large N-terminal extracellular domain of leucine rich repeat containing G protein-coupled receptor 6 (LGR6), and competitively blocked the binding of R-spondin 1, which is known to be the ligand for LGR6. PMID: 28013222
    5. LGR6 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    6. Overexpression of wild-type LGR6 in HeLa cells leads to increased cell migration. PMID: 22615920

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 19719

    OMIM: 606653

    KEGG: hsa:59352

    STRING: 9606.ENSP00000356247

    UniGene: Hs.497402



主站蜘蛛池模板： 无码区国产区在线播放| 亚洲精品suv精品一区二区| 国产日本精品视频在线观看| av国産精品毛片一区二区视频 | 日韩在线 | 中文| 最新国产在线拍揄自揄视频| 高中生自慰www网站| 日本三级韩国三级欧美三级| 九九热线精品视频16| 日日碰狠狠躁久久躁9| 亚洲欧美精品午睡沙发| 国产三级久久久精品麻豆三级| 欧美日韩精品无码一本二本三本色| 久久久女人与动物群交毛片| 国产亚洲精品久久久久丝瓜| 国产人妻人伦精品1国产丝袜| 青青草国产精品一区二区| 沈阳熟女露脸对白视频| 无码免费一区二区三区| 亚洲国产精品成人天堂| 巨大乳做爰视频在线看| 国产成人精品免费视频大全软件| 大胸少妇午夜三级| 久久精品中文字幕无码绿巨人| 亚洲人成精品久久久久桥| 一边做一边喷17p亚洲乱妇50p| 天堂网www在线资源网| 四虎国产成人永久精品免费| 欧美猛少妇色xxxxx猛交| 欧美人禽zozo动人物杂交| 绝顶丰满少妇av无码| 天天看片视频免费观看| 国产sp调教打屁股视频网站| 国产精品永久在线观看| 日韩精品中文字幕无码一区| 狠狠狠色丁香综合婷婷久久| 亚洲欧洲精品成人久久曰影片| 国产麻花豆剧传媒精品mv在线| 美女裸体十八禁免费网站| 免费能直接看黄的视频| 亚洲成a人片在线观看天堂无码|