在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LGR6 Antibody

LGR6 Antibody

  • 中文名稱：
    LGR6兔多克隆抗體
  • 貨號：
    CSB-PA012907GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ14471 antibody; Gonadotropin receptor antibody; GPCR antibody; Leucine rich repeat containing G protein coupled receptor 6 antibody; Leucine-rich repeat-containing G-protein coupled receptor 6 antibody; Lgr6 antibody; LGR6_HUMAN antibody; VTS20631 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human LGR6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
  • 基因功能參考文獻：
    1. Inhibition of LGR6 promoted the osteogenic differentiation of bone marrow stromal cells in vitro. PMID: 29625528
    2. Lgr6 has a tumorpromoting role in the development of colorectal cancer. PMID: 29693156
    3. Lgr6 marks mammary gland progenitor cells that can initiate tumours, and cells of luminal breast tumours required for efficient tumour maintenance. PMID: 27798604
    4. Two of the three monoclonal antibodies recognized the large N-terminal extracellular domain of leucine rich repeat containing G protein-coupled receptor 6 (LGR6), and competitively blocked the binding of R-spondin 1, which is known to be the ligand for LGR6. PMID: 28013222
    5. LGR6 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    6. Overexpression of wild-type LGR6 in HeLa cells leads to increased cell migration. PMID: 22615920

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：

    HGNC: 19719

    OMIM: 606653

    KEGG: hsa:59352

    STRING: 9606.ENSP00000356247

    UniGene: Hs.497402



主站蜘蛛池模板： 在厨房拨开内裤进入毛片| 亚洲精品gv天堂无码男同| 美丽的熟妇中文字幕| 婷婷无套内射影院| 久久激情日本亚洲欧洲国产中文| 天堂网在线www资源| 制服丝袜另类专区制服| 久久免费的精品国产v∧| 亚洲中文在线播放一区| 亚洲成av人片在线观看橙子| 久久久久久久久888| 香港三日本8a三级少妇三级99| 国产亚洲日本精品成人专区| 五月丁香六月综合缴情在线| 先锋影音男人av资源| 人人澡超碰碰97碰碰碰| 青青青草国产线观| 把腿张开老子臊烂你多p视频| 精品久久无码中文字幕| 欧美乱妇高清无乱码免费| 琪琪秋霞午夜av影视在线| 亚洲综合久久成人a片| 免费无遮挡无码永久在线观看视频| 人妻系列无码专区久久五月天| 美女mm131午夜福利在线| 国产午夜高潮熟女精品av软件| 内射老妇bbwx0c0ck| 免费观看潮喷到高潮中文字幕| 亚洲午夜久久久无码精品网红a片 国产亚洲日韩一区二区三区 | 最新国产精品久久精品| 国产精品久久久久久久久久久久人四虎| 国产三级精品三级在专区| 国产精品人成在线播放新网站| 亚洲精品无码鲁网午夜| 国产又粗又猛又大爽又黄| 直接观看黄网站免费视频| 日韩免费无砖专区2020狼 | 日韩av无码中文字幕| 久久99精品国产自在现线小黄鸭 | 无码av高潮抽搐流白浆| 亚洲欧洲日产最新|