在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. LGR6 Antibody

LGR6 Antibody

  • 中文名稱：
    LGR6兔多克隆抗體
  • 貨號：
    CSB-PA012907GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ14471 antibody; Gonadotropin receptor antibody; GPCR antibody; Leucine rich repeat containing G protein coupled receptor 6 antibody; Leucine-rich repeat-containing G-protein coupled receptor 6 antibody; Lgr6 antibody; LGR6_HUMAN antibody; VTS20631 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human LGR6
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.
  • 基因功能參考文獻：
    1. Inhibition of LGR6 promoted the osteogenic differentiation of bone marrow stromal cells in vitro. PMID: 29625528
    2. Lgr6 has a tumorpromoting role in the development of colorectal cancer. PMID: 29693156
    3. Lgr6 marks mammary gland progenitor cells that can initiate tumours, and cells of luminal breast tumours required for efficient tumour maintenance. PMID: 27798604
    4. Two of the three monoclonal antibodies recognized the large N-terminal extracellular domain of leucine rich repeat containing G protein-coupled receptor 6 (LGR6), and competitively blocked the binding of R-spondin 1, which is known to be the ligand for LGR6. PMID: 28013222
    5. LGR6 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    6. Overexpression of wild-type LGR6 in HeLa cells leads to increased cell migration. PMID: 22615920

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 數據庫鏈接：

    HGNC: 19719

    OMIM: 606653

    KEGG: hsa:59352

    STRING: 9606.ENSP00000356247

    UniGene: Hs.497402



主站蜘蛛池模板： 欧美亚洲色aⅴ大片| 久久久久久av无码免费网站| 免费裸体无遮挡黄网站免费看| 国产精品无码专区| 国产另类ts人妖一区二区| 国产在线 | 欧洲| 99精品丰满人妻无码a片| 国产成人av大片在线播放| 国产东北肥熟老胖女| 国模冰莲极品自慰人体| 国产嫖妓风韵犹存对白| 98久久人妻少妇激情啪啪| 少妇扒开双腿让我看个够| 吃奶揉捏奶头高潮视频| 久久午夜伦鲁片免费无码| 欧洲熟妇色xxxx欧美老妇多毛网站 | 中文字幕色av一区二区三区| 边啃奶头边躁狠狠躁| 国产桃色无码视频在线观看| 国产一卡2卡3卡4卡精品| 99久久精品国产免费| 男人用嘴添女人下身免费视频 | 香港三级韩国三级日本三级| 精品亚洲成a人在线观看青青 | 中文字幕aⅴ人妻一区二区| 真人做作爱视频| 欧美国产精品久久久乱码| 伊人色合天天久久综合网| 久久天天躁狠狠躁夜夜avapp| 边吃奶边添下面好爽| 日韩爆乳一区二区无码| 好爽好硬好深高潮视频456| 夜夜影院未满十八勿进| 玩弄人妻少妇500系列网址| 免费人成网站在线观看视频| 久久无码高潮喷水| 又粗又大又硬又长又爽| 又色又爽又高潮免费观看| 麻豆精品偷拍人妻在线网址| 国产极品粉嫩泬免费观看| 国产乱对白刺激视频|