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  4. LEMD2 Antibody, HRP conjugated

LEMD2 Antibody, HRP conjugated

  • 中文名稱：
    LEMD2兔多克隆抗體, HRP偶聯(lián)
  • 貨號：
    CSB-PA854097LB01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) LEMD2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    LEMD2
  • 別名：
    LEMD2; LEM domain-containing protein 2; hLEM2
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human LEM domain-containing protein 2 protein (17-204AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Involved in nuclear structure organization. Required for maintaining the integrity of the nuclear envelope.; Required for embryonic development and is involved in regulation of several signaling pathways such as MAPK and AKT. Required for myoblast differentiation involving regulation of ERK signaling.
  • 基因功能參考文獻：
    1. We conclude that Lem2p/LEM2 is a conserved nuclear site-specific adaptor that recruits Cmp7p/CHMP7 and downstream ESCRT factors to the nuclear envelope. PMID: 28242692
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851445
  • 相關疾病：
    Cataract 46, juvenile-onset (CTRCT46)
  • 亞細胞定位：
    Nucleus inner membrane; Multi-pass membrane protein. Note=Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery.
  • 組織特異性：
    Ubiquitously expressed.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 21244

    OMIM: 212500

    KEGG: hsa:221496

    STRING: 9606.ENSP00000293760

    UniGene: Hs.444845



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