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LEMD2 Antibody, FITC conjugated

  • 中文名稱:
    LEMD2兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA854097LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) LEMD2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    LEMD2
  • 別名:
    LEMD2; LEM domain-containing protein 2; hLEM2
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human LEM domain-containing protein 2 protein (17-204AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in nuclear structure organization. Required for maintaining the integrity of the nuclear envelope.; Required for embryonic development and is involved in regulation of several signaling pathways such as MAPK and AKT. Required for myoblast differentiation involving regulation of ERK signaling.
  • 基因功能參考文獻:
    1. We conclude that Lem2p/LEM2 is a conserved nuclear site-specific adaptor that recruits Cmp7p/CHMP7 and downstream ESCRT factors to the nuclear envelope. PMID: 28242692
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851445
  • 相關疾病:
    Cataract 46, juvenile-onset (CTRCT46)
  • 亞細胞定位:
    Nucleus inner membrane; Multi-pass membrane protein. Note=Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim-like staining of the nuclear periphery.
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 21244

    OMIM: 212500

    KEGG: hsa:221496

    STRING: 9606.ENSP00000293760

    UniGene: Hs.444845



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