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  4. KY Antibody, FITC conjugated

KY Antibody, FITC conjugated

  • 中文名稱：
    KY兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA012702LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KY Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KY
  • 別名：
    KY antibody; KY_HUMAN antibody; Kyphoscoliosis peptidase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Kyphoscoliosis peptidase protein (23-170AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC.
  • 基因功能參考文獻：
    1. This study shown Kyphoscoliosis peptidase (KY) mutation causes a novel congenital myopathy with core targetoid defects in two bother. PMID: 27484770
    2. Homozygous KY mutation was identified as a cause of progressive hereditary spastic paraplegia. High KY transcript levels were demonstrated in muscular organs and lower expression in the CNS. PMID: 28488683
    3. Homozygous c.1071delG, p.(Thr358Leufs*3) variant of KY causes neuromuscular disorder by introducing a premature stop codon. PMID: 27485408
    4. KY expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
    5. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614

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  • 相關疾病：
    Myopathy, myofibrillar, 7 (MFM7)
  • 亞細胞定位：
    Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line.
  • 蛋白家族：
    Transglutaminase-like superfamily
  • 組織特異性：
    Highly expressed in skeletal muscle.
  • 數據庫鏈接：

    HGNC: 26576

    OMIM: 605739

    KEGG: hsa:339855

    STRING: 9606.ENSP00000397598

    UniGene: Hs.146730



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