在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. KPNA4 Antibody, FITC conjugated

KPNA4 Antibody, FITC conjugated

  • 中文名稱：
    KPNA4兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA012486LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) KPNA4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    KPNA4
  • 別名：
    FLJ31113 antibody; IMA3_HUMAN antibody; Importin alpha 3 antibody; Importin alpha 4 subunit antibody; Importin alpha Q1 antibody; Importin subunit alpha 3 antibody; Importin subunit alpha-3 antibody; IPO A3 antibody; IPOA 3 antibody; IPOA3 antibody; Karyopherin alpha 4 (importin alpha 3) antibody; Karyopherin alpha 4 antibody; Karyopherin alpha 4 importin alpha 3 antibody; Karyopherin alpha 4 subunit antibody; Karyopherin subunit alpha 4 antibody; Karyopherin subunit alpha-4 antibody; KPNA 4 antibody; Kpna4 antibody; MGC12217 antibody; MGC26703 antibody; OTTHUMP00000213880 antibody; QIP 1 antibody; Qip1 antibody; Qip1 protein antibody; SRP 3 antibody; SRP3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Importin subunit alpha-3 protein (51-239AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS. In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.
  • 基因功能參考文獻：
    1. Importin alpha3 facilitates the nuclear transport of the Ran guanine nucleotide exchange factor RCC1. PMID: 29042532
    2. Our results suggest a potential role of Hsa-miR-567 as a novel prognostic biomarker for BC and as regulator of KPNA4. PMID: 28000015
    3. Our results showed that miR-181 family expression was closely correlated with TCGA subtypes and patients' overall survival, indicating that miR-181b. PMID: 26283154
    4. upon DNA damage transport adaptor importin-alpha4 imports XPA into the nucleus in an ATR-dependent manner. PMID: 23861882
    5. Importin alpha3/Qip1 is involved in multiplication of mutant influenza virus with alanine mutation at amino acid 9 independently of nuclear transport function. PMID: 23383277
    6. Impalpha3 is an HIV integrase-interacting cofactor and is required for efficient HIV-1 nuclear import and replication. PMID: 20554775
    7. stress-induced accumulation of non-ubiquitinated p53 in the cytoplasm promotes interaction with importin-alpha3 and rapid import PMID: 19927155
    8. Expression of importin alpha3, a protein involved in p50/p65 nuclear import, was decreased in cells overexpressing PHB. PMID: 19710421
    9. Our results indicate that the nuclear import of RHA is mediated by the importin-alpha3/importin-beta-dependent pathway and suggest that the specificity for importin may regulate the functions of cargo proteins. PMID: 16375861
    10. Daxx interacts selectively with importin alpha3 through its NLS1 and NLS2 sequences. Conversely, importin alpha3 utilizes two NLS-binding sites for Daxx interaction, suggesting that it mediates nuclear import of Daxx. PMID: 17661348

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Importin alpha family
  • 組織特異性：
    Highly expressed in testis, ovary, small intestine, heart, skeletal muscle, lung and pancreas, but barely detectable in kidney, thymus, colon and peripheral blood leukocytes.
  • 數據庫鏈接：

    HGNC: 6397

    OMIM: 602970

    KEGG: hsa:3840

    STRING: 9606.ENSP00000334373

    UniGene: Hs.467866



主站蜘蛛池模板： 老色69久久九九精品高潮| 久久人人爽人人爽爽久久小说| 久久国产福利播放| 后入到高潮免费观看| 女人18片毛片60分钟| 久久精品免费国产大片| 日韩免费人妻av无码专区蜜桃| 亚洲国产a∨无码中文777| 欧美老熟妇xb水多毛多| 一区二区三区波多野结衣在线观看| 免费看女人与公拘交酡过程| 午夜dj在线观看高清在线视频完整版| 污污内射久久一区二区欧美日韩| 亚洲精品国产熟女久久久| 男女下面一进一出好爽视频| 动漫无遮挡h纯肉亚洲资源大片| 国产精品.xx视频.xxtv| 色婷婷久久综合中文久久一本| 欧美人与动zozo在线播放| 少妇无码av无码专区| 国产乱人伦av在线无码| 精品国精品自拍自在线| 精品成人毛片一区二区| 精产一二三产区m553| 人妻无码中文专区久久app| 亚洲欲色欲色xxxxx在线观看| 野外性史欧美k8播放| 免费三级网站| 中文字幕av高清片| 西西艺术人像摄影| 96国产xxxx免费视频| 天天噜日日噜狠狠噜免费 | 久久人妻无码一区二区| 中文文字幕文字幕亚洲色| 无码免费h成年动漫在线观看 | 日韩国产精品无码一区二区三区 | 极品新婚夜少妇真紧| 老司机亚洲精品影院无码| 蜜桃日本免费观看mv| 99久久er热在这里只有精品99| 久久精品一区二区三区av|