在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KLK2 Antibody

  • 中文名稱:
    KLK2兔多克隆抗體
  • 貨號(hào):
    CSB-PA012453LA01HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA012453LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA012453LA01HU at dilution of 1:100
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) KLK2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Glandular kallikrein 2 antibody; Glandular kallikrein-1 antibody; hGK 1 antibody; hGK-1 antibody; hK2 antibody; Kallikrein 2 prostatic antibody; Kallikrein related peptidase 2 antibody; kallikrein, glandular antibody; Kallikrein, prostatic antibody; Kallikrein-2 antibody; KLK 2 antibody; Klk-2 antibody; Klk2 antibody; KLK2_HUMAN antibody; KLK2A 2 antibody; KLK2A2 antibody; MGC12201 antibody; Tissue kallikrein 2 antibody; Tissue kallikrein-2 antibody; Ton antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Kallikrein-2 protein (25-261AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated

    本頁(yè)面中的產(chǎn)品,KLK2 Antibody (CSB-PA012453LA01HU),的標(biāo)記方式是Non-conjugated。對(duì)于KLK2 Antibody,我們還提供其他標(biāo)記。見(jiàn)下表:

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA012453LB01HU KLK2 Antibody, HRP conjugated ELISA
    FITC CSB-PA012453LC01HU KLK2 Antibody, FITC conjugated
    Biotin CSB-PA012453LD01HU KLK2 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
  • 基因功能參考文獻(xiàn):
    1. glycosylation changes the enzymatic activity of KLK2 in a drastically substrate-dependent manner. PMID: 26582203
    2. The results indicated that W-hK2 had a defect in cellular trafficking due to its misfolding and that it activated the unfolded protein response, suggesting a mechanism to explain the association of the T allele with higher prostate cancer risk. PMID: 25847286
    3. miR-378 was predicted to target both KLK2 and KLK4 and downregulated levels detected in prostate cancer patients. PMID: 25153390
    4. The differential regulation of alternative transcripts (using KLK2, KLK3 and KLK4 as models) by androgens and anti-androgens as an indicator of prostate cancers, was investigated. PMID: 25153393
    5. Structure-function analyses of KLK2 establish the 99-loop as master regulator of its activity. PMID: 25326387
    6. Predictions based on levels of four kallikrein markers, including KLK2, in blood distinguish between pathologically insignificant and aggressive disease after radical prostatectomy with good accuracy. PMID: 23683475
    7. Alteration of cellular junctions in benign prostatic hyperplasia could contribute to the presence of luminal epithelial secreted proteins prostate specific antigen (PSA)2 and and KLK2 in the stromal compartment. PMID: 24711254
    8. we present the first evidence that KLK2 can also function as an androgen receptor modulator that may modulate cell growth after the development of castration-resistant prostate cancer PMID: 24122203
    9. Associations observed in young, healthy men between the seminal plasma and serum concentrations of hK2 and PSA and several genetic variants in KLK2 and KLK3 could be useful to refine models of PSA cutoff values in prostate cancer testing. PMID: 24270797
    10. Genetic variants at ATF7IP and KLK2 contribute to the variance of %fPSA. PMID: 23359319
    11. Two SNPs, in beta-microseminoprotein at and in kallikrein-related peptidase 2 at, are associated with PCA3 score at genome-wide significance level PMID: 23555189
    12. TK promotes vessel growth by increasing the number of EPCs and enhancing their functional properties through the kinin B(2) receptor-Akt signaling pathway. PMID: 22435954
    13. An exploratory study of a KLK2 polymorphism as a prognostic marker in prostate cancer was found to be less likely associated with low Gleason score morphology. PMID: 21178268
    14. we identifiedand genotyped novel single-nucleotide polymorphisms in cancer cases and controls which verified prior associations in KLK2 and in MSMB (but not in KLK3) with prostate cancer PMID: 20424135
    15. Data show six non-synonymous amino acid or frame shift changes in the KLK3 gene and three changes in each of the neighboring genes, KLK15 and KLK2. PMID: 19823874
    16. The identification of unusual mRNA splice variants of the KLK2 and KLK3 genes that result from inclusion of intronic sequences adjacent to the first exon. PMID: 11834722
    17. Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3. PMID: 12124798
    18. kallikrein expression in nipple aspirate fluid- ethnic variation PMID: 12209605
    19. Measurements of free prostate specific antigen and hK2 improve on our ability to counsel patients prior to treatment as to their risk of biochemical recurrence PMID: 16152616
    20. An additional serum marker for the detection of prostatic cancer. PMID: 16388506
    21. a role for the KLK2 gene in prostate cancer susceptibility PMID: 17085659
    22. results imply that prostate cancer risk is associated with androgen receptor(AR)-CAG repeat and kallikrein-2 polymorphisms in Indian population but no unambiguous association was observed with PSA and AR-GGN repeat polymorphism PMID: 17257635
    23. role of kallikrein gene 2 and 3 variant SNPs in the etiology of prostate cancer among men of European ancestry PMID: 17593395
    24. %fPSA and hK2 add important predictive value in older men and much closer to diagnosis PMID: 17657743
    25. The two novel ETV4 fusion partners possess as predominant common characteristics androgen-induction and prostate-specific expression. PMID: 18451133
    26. Recombinant hK2 activates ERK1/2 signaling of prostate cancer cell lines, which express both PAR1 and PAR2. PMID: 18567807
    27. adding free PSA and human kallikrein 2 to standard pretreatment risk-assessment models to predict biochemical recurrence after radical prostatectomy for prostate cancer enhanced the AUC PMID: 19003994
    28. PSA and kallikrein 2 transcripts in the peripheral blood of prostate cancer patients during barchytherapy could serve as a predictor of biochemiacl outcome. PMID: 19434652
    29. Observational study of gene-disease association, gene-gene interaction, and genetic testing. (HuGE Navigator) PMID: 19223501

    顯示更多

    收起更多

  • 蛋白家族:
    Peptidase S1 family, Kallikrein subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 6363

    OMIM: 147960

    KEGG: hsa:3817

    STRING: 9606.ENSP00000313581

    UniGene: Hs.515560



主站蜘蛛池模板: 色综合天天天天综合狠狠爱| 人人妻人人做人人爽| 中文乱码免费一区二区| 99热久久这里只精品国产www | 亚洲精品av无码喷奶水网站| 色狠狠av老熟女| 久99久无码精品视频免费播放| 亚在线第一国产州精品99| 亚洲 欧美 国产 动漫 综合| 97伦伦午夜电影理伦片| 亚洲国产精品久久亚洲精品| 女人的天堂a国产在线观看| 亚洲一区二区av在线观看| 一本一道人人妻人人妻αv | 99re久久精品国产| 亚洲v国产v欧美v久久久久久| 亚洲2020天天堂在线观看| 中文字幕日韩人妻无码| 亚洲愉拍99热成人精品| 大香伊蕉在人线国产网站首页| 日本熟妇美熟bbw| 樱桃视频影视在线观看免费| 国产精品永久免费视频| 少妇与子乱在线观看| 国产乱码一区二区三区爽爽爽 | www国产成人免费观看视频| 97人妻无码一区| 国内精品久久久久久久电影视 | 日本欧美一区二区三区乱码| 午夜精品久久久久久久久久久久| 久久婷婷五月综合色d啪| 成人爽a毛片在线视频| 久久久久成人精品无码| 中文天堂在线www最新版官网| 狠狠色噜噜狠狠狠狠米奇777 | 美女大量吞精在线观看456| 狠狠色噜噜狠狠狠777米奇小说| 无码中出人妻中文字幕av| 闺蜜张开腿让我爽了一夜| 97人妻人人做人碰人人爽| 国内精品久久久久影视|