在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KLK2 Antibody

  • 中文名稱:
    KLK2兔多克隆抗體
  • 貨號:
    CSB-PA039286
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA039286(KLK2 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA039286(KLK2 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Glandular kallikrein 2 antibody; Glandular kallikrein-1 antibody; hGK 1 antibody; hGK-1 antibody; hK2 antibody; Kallikrein 2 prostatic antibody; Kallikrein related peptidase 2 antibody; kallikrein, glandular antibody; Kallikrein, prostatic antibody; Kallikrein-2 antibody; KLK 2 antibody; Klk-2 antibody; Klk2 antibody; KLK2_HUMAN antibody; KLK2A 2 antibody; KLK2A2 antibody; MGC12201 antibody; Tissue kallikrein 2 antibody; Tissue kallikrein-2 antibody; Ton antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human KLK2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
  • 基因功能參考文獻:
    1. glycosylation changes the enzymatic activity of KLK2 in a drastically substrate-dependent manner. PMID: 26582203
    2. The results indicated that W-hK2 had a defect in cellular trafficking due to its misfolding and that it activated the unfolded protein response, suggesting a mechanism to explain the association of the T allele with higher prostate cancer risk. PMID: 25847286
    3. miR-378 was predicted to target both KLK2 and KLK4 and downregulated levels detected in prostate cancer patients. PMID: 25153390
    4. The differential regulation of alternative transcripts (using KLK2, KLK3 and KLK4 as models) by androgens and anti-androgens as an indicator of prostate cancers, was investigated. PMID: 25153393
    5. Structure-function analyses of KLK2 establish the 99-loop as master regulator of its activity. PMID: 25326387
    6. Predictions based on levels of four kallikrein markers, including KLK2, in blood distinguish between pathologically insignificant and aggressive disease after radical prostatectomy with good accuracy. PMID: 23683475
    7. Alteration of cellular junctions in benign prostatic hyperplasia could contribute to the presence of luminal epithelial secreted proteins prostate specific antigen (PSA)2 and and KLK2 in the stromal compartment. PMID: 24711254
    8. we present the first evidence that KLK2 can also function as an androgen receptor modulator that may modulate cell growth after the development of castration-resistant prostate cancer PMID: 24122203
    9. Associations observed in young, healthy men between the seminal plasma and serum concentrations of hK2 and PSA and several genetic variants in KLK2 and KLK3 could be useful to refine models of PSA cutoff values in prostate cancer testing. PMID: 24270797
    10. Genetic variants at ATF7IP and KLK2 contribute to the variance of %fPSA. PMID: 23359319
    11. Two SNPs, in beta-microseminoprotein at and in kallikrein-related peptidase 2 at, are associated with PCA3 score at genome-wide significance level PMID: 23555189
    12. TK promotes vessel growth by increasing the number of EPCs and enhancing their functional properties through the kinin B(2) receptor-Akt signaling pathway. PMID: 22435954
    13. An exploratory study of a KLK2 polymorphism as a prognostic marker in prostate cancer was found to be less likely associated with low Gleason score morphology. PMID: 21178268
    14. we identifiedand genotyped novel single-nucleotide polymorphisms in cancer cases and controls which verified prior associations in KLK2 and in MSMB (but not in KLK3) with prostate cancer PMID: 20424135
    15. Data show six non-synonymous amino acid or frame shift changes in the KLK3 gene and three changes in each of the neighboring genes, KLK15 and KLK2. PMID: 19823874
    16. The identification of unusual mRNA splice variants of the KLK2 and KLK3 genes that result from inclusion of intronic sequences adjacent to the first exon. PMID: 11834722
    17. Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3. PMID: 12124798
    18. kallikrein expression in nipple aspirate fluid- ethnic variation PMID: 12209605
    19. Measurements of free prostate specific antigen and hK2 improve on our ability to counsel patients prior to treatment as to their risk of biochemical recurrence PMID: 16152616
    20. An additional serum marker for the detection of prostatic cancer. PMID: 16388506
    21. a role for the KLK2 gene in prostate cancer susceptibility PMID: 17085659
    22. results imply that prostate cancer risk is associated with androgen receptor(AR)-CAG repeat and kallikrein-2 polymorphisms in Indian population but no unambiguous association was observed with PSA and AR-GGN repeat polymorphism PMID: 17257635
    23. role of kallikrein gene 2 and 3 variant SNPs in the etiology of prostate cancer among men of European ancestry PMID: 17593395
    24. %fPSA and hK2 add important predictive value in older men and much closer to diagnosis PMID: 17657743
    25. The two novel ETV4 fusion partners possess as predominant common characteristics androgen-induction and prostate-specific expression. PMID: 18451133
    26. Recombinant hK2 activates ERK1/2 signaling of prostate cancer cell lines, which express both PAR1 and PAR2. PMID: 18567807
    27. adding free PSA and human kallikrein 2 to standard pretreatment risk-assessment models to predict biochemical recurrence after radical prostatectomy for prostate cancer enhanced the AUC PMID: 19003994
    28. PSA and kallikrein 2 transcripts in the peripheral blood of prostate cancer patients during barchytherapy could serve as a predictor of biochemiacl outcome. PMID: 19434652
    29. Observational study of gene-disease association, gene-gene interaction, and genetic testing. (HuGE Navigator) PMID: 19223501

    顯示更多

    收起更多

  • 蛋白家族:
    Peptidase S1 family, Kallikrein subfamily
  • 數據庫鏈接:

    HGNC: 6363

    OMIM: 147960

    KEGG: hsa:3817

    STRING: 9606.ENSP00000313581

    UniGene: Hs.515560



主站蜘蛛池模板: 中文字幕av伊人av无码av狼人| 免费男人下部进女人下部视频 | 亚洲va在线va天堂xxxx中文| 亚洲va久久久噜噜噜久久无码| 中文字幕亚洲码在线观看| 成人做爰69片免费看网站| 国产免费观看黄av片| 中文字幕乱码亚洲无线码三区| 日韩不卡1卡2卡三卡网站| 无码国内精品人妻少妇蜜桃视频| 都市激情 在线 亚洲 国产| 亚洲成片在线观看12345| 囯产精品一区二区三区线| 国产成人精品无码一区二区| 国产麻豆精品久久一二三| 亚洲综合无码一区二区痴汉| 免费观看性欧美大片无片| 超碰人人超碰人人| 在线aⅴ亚洲中文字幕| 好男人在在线社区www在线影院| 草草地址线路①屁屁影院成人 | 国产超碰人人做人人爱| 国产精品无套呻吟在线| 女人被狂躁60分钟视频| 十八禁啪啪无遮挡网站| 国产日产高清欧美一区| 特大巨黑吊xxxx高潮| 国产色播av在线观看| 亚洲男人的天堂成人www| 性少妇无码播放| 日韩精品无码一区二区| 亚洲h成年动漫在线观看网站| 中文无码一区二区三区在线观看| 十八禁视频网站在线观看| 午夜片无码区在线观看视频| 精品一区国产vr| 少妇人妻邻居| 国产精品亚洲精品日韩已满十八小 | 国产乱妇无乱码大黄aa片| 欧美肥婆性猛交xxxx| 小13箩利洗澡无码视频网站|