在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KIF1C Antibody

  • 中文名稱:
    KIF1C兔多克隆抗體
  • 貨號:
    CSB-PA969739
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human placenta tissue using CSB-PA969739(KIF1C Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human sarcoma tissue using CSB-PA969739(KIF1C Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    KIF1C
  • 別名:
    Kif1c antibody; KIF1C_HUMAN antibody; Kinesin family member 1C antibody; Kinesin-like protein KIF1C antibody; LTXS1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human KIF1C
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.
  • 基因功能參考文獻:
    1. Hereditary spastic paraplegia (HSP) patients with KIF1C mutations may present with cerebellar signs and pyramidal findings may emerge later, therefore complicated HSP should be considered in the differential diagnosis of unidentified cases with cerebellar dysfunction. PMID: 29544888
    2. Rab6A binding to KIF1C's motor domain represents an entirely new mode of regulation for a kinesin motor, and likely has important consequences for KIF1C's cellular functions. PMID: 25821985
    3. KIF1C translocation to the cell periphery intensifies and KIF1C accumulates both in the proximity of peripheral microtubules that show enrichment for the plus-tip-associated proteins CLASPs and around podosomes. PMID: 25344256
    4. Microtubule acetylation influences the subcellular distribution of vesicles associated with the kinesin KIF1C, as well as their directionality, velocity and run length. PMID: 25151635
    5. Nonsense and missense mutations in the KIF1C gene associated with hereditary spastic paraparesis and cerebellar dysfunction. PMID: 24319291
    6. Identification of KIF1C as an hereditary spastic paraplegia gene supports the key role of intracellular trafficking processes in the pathogenesis of hereditary axonopathies. PMID: 24808017
    7. findings show that the microtubule motor Kif1C contributes to persistent cell migration primarily through stabilization of an extended cell rearKif1C-mediated transport of alpha5beta1-integrins is required for the proper maturation of trailing focal adhesions and resistance to tail retraction PMID: 23237952
    8. Hairpin RNA-based depletion of KIF1C resulted in decreased podosome dynamics and ultimately in podosome deficiency. PMID: 16554367

    顯示更多

    收起更多

  • 相關疾病:
    Spastic ataxia 2, autosomal recessive (SPAX2)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Unc-104 subfamily
  • 組織特異性:
    Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 6317

    OMIM: 603060

    KEGG: hsa:10749

    STRING: 9606.ENSP00000320821

    UniGene: Hs.435120



主站蜘蛛池模板: 欧美国产日韩a欧美在线观看| xx性欧美肥妇精品久久久久久| 色妞色视频一区二区三区四区| 亚洲日韩av无码中文字幕美国| 日韩欧美一中文字暮专区| 国产女人高潮抽搐叫床视频| 激情97综合亚洲色婷婷五| 99久久国产露脸精品竹菊传媒| 中文字幕日韩人妻无码| 一本一道av无码中文字幕﹣百度| 国模叶桐尿喷337p人体| 国产高潮抽搐喷水高清| 99热成人精品国产免费 | 免费毛片全部不收费的| 欧美人与物videos另类xxxxx| 青青青青国产免费线在线观看| 欧美性猛交xxxxx按摩欧美| 久热国产精品视频一区二区三区| 国产午夜亚洲精品不卡下载| 国产农村妇女精品一二区| 中出あ人妻熟女中文字幕| 精品人妻伦一二三区久久aaa片| 18禁午夜宅男成年网站| 麻豆精品久久久久久久99蜜桃| 久久精品国产精品| 99热成人精品热久久6网站 | 2019久久久最新精品| 欧美成人片一区二区三区| 一区二区三区人妻无码| 婷婷丁香五月六月综合激情啪| 国产在线观看高清视频黄网| 国产成人a人亚洲精v品无码| 国产l精品国产亚洲区久久| 免费无码午夜福利片| 欧美综合乱图图区乱图图区| 成 人 网 站 免费 在线| 香蕉av777xxx色综合一区| 久久久老熟女一区二区三区| 清纯唯美经典一区二区| 狠狠做五月深爱婷婷伊人| 国产精品xxx在线|