在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KIF1C Antibody

  • 中文名稱:
    KIF1C兔多克隆抗體
  • 貨號:
    CSB-PA969739
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human placenta tissue using CSB-PA969739(KIF1C Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human sarcoma tissue using CSB-PA969739(KIF1C Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    KIF1C
  • 別名:
    Kif1c antibody; KIF1C_HUMAN antibody; Kinesin family member 1C antibody; Kinesin-like protein KIF1C antibody; LTXS1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human KIF1C
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.
  • 基因功能參考文獻:
    1. Hereditary spastic paraplegia (HSP) patients with KIF1C mutations may present with cerebellar signs and pyramidal findings may emerge later, therefore complicated HSP should be considered in the differential diagnosis of unidentified cases with cerebellar dysfunction. PMID: 29544888
    2. Rab6A binding to KIF1C's motor domain represents an entirely new mode of regulation for a kinesin motor, and likely has important consequences for KIF1C's cellular functions. PMID: 25821985
    3. KIF1C translocation to the cell periphery intensifies and KIF1C accumulates both in the proximity of peripheral microtubules that show enrichment for the plus-tip-associated proteins CLASPs and around podosomes. PMID: 25344256
    4. Microtubule acetylation influences the subcellular distribution of vesicles associated with the kinesin KIF1C, as well as their directionality, velocity and run length. PMID: 25151635
    5. Nonsense and missense mutations in the KIF1C gene associated with hereditary spastic paraparesis and cerebellar dysfunction. PMID: 24319291
    6. Identification of KIF1C as an hereditary spastic paraplegia gene supports the key role of intracellular trafficking processes in the pathogenesis of hereditary axonopathies. PMID: 24808017
    7. findings show that the microtubule motor Kif1C contributes to persistent cell migration primarily through stabilization of an extended cell rearKif1C-mediated transport of alpha5beta1-integrins is required for the proper maturation of trailing focal adhesions and resistance to tail retraction PMID: 23237952
    8. Hairpin RNA-based depletion of KIF1C resulted in decreased podosome dynamics and ultimately in podosome deficiency. PMID: 16554367

    顯示更多

    收起更多

  • 相關疾病:
    Spastic ataxia 2, autosomal recessive (SPAX2)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Unc-104 subfamily
  • 組織特異性:
    Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 6317

    OMIM: 603060

    KEGG: hsa:10749

    STRING: 9606.ENSP00000320821

    UniGene: Hs.435120



主站蜘蛛池模板: 亚洲一区二区三区无码久久| 成人片黄网站色大片免费毛片| 亚洲男人av香蕉爽爽爽爽| 内射人妻视频国内| 亚洲欧洲成人a∨在线观看| 国产精品亚洲第一区在线观看 | 国产精品久久久久久亚洲毛片| 欧美疯狂性受xxxxx喷水| 国产午夜aaaaa片在线影院| 欧美白人最猛性xxxxx| 国产成人无码一区二区三区| 免费无码国产v片在线观看| 国产69囗曝吞精在线视频| 东京一本一道一二三区| 67194熟妇在线观看线路1| 永久免费无码日韩视频| 国产成人卡2卡3卡4乱码| 久久天天躁狠狠躁夜夜96流白浆| 国产亚洲精品俞拍视频| 免费无遮挡无码视频网站| 久久青青草原精品国产app| 国产成人啪精品午夜网站a片免费| 波多野结衣在线观看一码 | 好想被狂躁无码视频在线观看| 亚洲精品无码不卡在线播he| 国产未发育呦交视频| 国产无遮挡免费真人视频在线观看 | 亚洲欧美日韩综合俺去了 | 国产精品香蕉在线的人| 久久精品aⅴ无码中文字字幕不卡| 男女性高爱潮免费观看| 国产伦精品一区二区三区免费| 曰本无码不卡高清av一二| 日本亚欧热亚洲乱色视频| 无码成人精品区在线观看| 久久久欧美国产精品人妻噜噜 | 精品国产肉丝袜久久| 真实国产乱啪福利露脸| 欧美成人秋霞久久aa片| 香蕉久久国产超碰青草| 国产精品无码无卡在线播放|