在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

KIF1C Antibody

  • 中文名稱:
    KIF1C兔多克隆抗體
  • 貨號:
    CSB-PA012320GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    KIF1C
  • 別名:
    Kif1c antibody; KIF1C_HUMAN antibody; Kinesin family member 1C antibody; Kinesin-like protein KIF1C antibody; LTXS1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human KIF1C
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Motor required for the retrograde transport of Golgi vesicles to the endoplasmic reticulum. Has a microtubule plus end-directed motility.
  • 基因功能參考文獻(xiàn):
    1. Hereditary spastic paraplegia (HSP) patients with KIF1C mutations may present with cerebellar signs and pyramidal findings may emerge later, therefore complicated HSP should be considered in the differential diagnosis of unidentified cases with cerebellar dysfunction. PMID: 29544888
    2. Rab6A binding to KIF1C's motor domain represents an entirely new mode of regulation for a kinesin motor, and likely has important consequences for KIF1C's cellular functions. PMID: 25821985
    3. KIF1C translocation to the cell periphery intensifies and KIF1C accumulates both in the proximity of peripheral microtubules that show enrichment for the plus-tip-associated proteins CLASPs and around podosomes. PMID: 25344256
    4. Microtubule acetylation influences the subcellular distribution of vesicles associated with the kinesin KIF1C, as well as their directionality, velocity and run length. PMID: 25151635
    5. Nonsense and missense mutations in the KIF1C gene associated with hereditary spastic paraparesis and cerebellar dysfunction. PMID: 24319291
    6. Identification of KIF1C as an hereditary spastic paraplegia gene supports the key role of intracellular trafficking processes in the pathogenesis of hereditary axonopathies. PMID: 24808017
    7. findings show that the microtubule motor Kif1C contributes to persistent cell migration primarily through stabilization of an extended cell rearKif1C-mediated transport of alpha5beta1-integrins is required for the proper maturation of trailing focal adhesions and resistance to tail retraction PMID: 23237952
    8. Hairpin RNA-based depletion of KIF1C resulted in decreased podosome dynamics and ultimately in podosome deficiency. PMID: 16554367

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Spastic ataxia 2, autosomal recessive (SPAX2)
  • 亞細(xì)胞定位:
    Cytoplasm, cytoskeleton.
  • 蛋白家族:
    TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, Unc-104 subfamily
  • 組織特異性:
    Expressed in all tissues examined, with most abundant expression in heart and skeletal muscle.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 6317

    OMIM: 603060

    KEGG: hsa:10749

    STRING: 9606.ENSP00000320821

    UniGene: Hs.435120



主站蜘蛛池模板: 亚洲成a人片在线观看天堂| 中文字字幕在线中文乱码| 亚洲人成网亚洲欧洲无码久久| 久久精品国产只有精品2020| 国产区精品福利在线社区| 无码人妻久久久一区二区三区| 亚洲 中文字幕 日韩 无码| 亚洲精品国产精品乱码视色| 国产片精品av在线观看夜色| 久久不见久久见免费视频1′| 久久久久久久99精品免费观看| 少妇被猛男粗大的猛进出| 免费国产va在线观看| 一本aⅴ高清一区二区三区| 99久久99久久免费精品蜜桃| 巨大黑人极品videos精品| 国产乱子伦三级在线播放| 国产超碰人人做人人爽av大片| 中文毛片无遮挡高潮免费| 国产精品无码一区二区三区电影 | 乱码av麻豆丝袜熟女系列| 国产xxxx做受视频| 国产精品青青青在线观看| 狠狠色丁香久久综合| 日韩一欧美内射在线观看| 99久无码中文字幕一本久道| 人妻少妇精品无码专区芭乐视网| 少妇人妻大乳在线视频| 伊人www22综合色| 美女被张开双腿日出白浆| 国产美女遭强高潮网站下载| 日日碰狠狠躁久久躁综合小说| 亚洲一本大道av久在线播放| 无码专区亚洲制服丝袜| 裸身美女无遮挡永久免费视频 | 久久人人爽爽人人爽人人片av| 亚洲不卡中文字幕无码| 亚洲欧洲无码av电影在线观看| 国产男女免费完整视频网页| 色婷婷综合激情综在线播放| 无码av中文字幕免费放|