在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. IYD Antibody

IYD Antibody

  • 中文名稱：
    IYD兔多克隆抗體
  • 貨號：
    CSB-PA754272LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of A549 cells with CSB-PA754272LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) IYD Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    IYD antibody; C6orf71 antibody; DEHAL1 antibody; Iodotyrosine deiodinase 1 antibody; IYD-1 antibody; EC 1.21.1.1 antibody; Iodotyrosine dehalogenase 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Iodotyrosine deiodinase 1 protein (24-147AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，IYD Antibody (CSB-PA754272LA01HU)，的標記方式是Non-conjugated。對于IYD Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA754272LB01HU IYD Antibody, HRP conjugated ELISA
    FITC CSB-PA754272LC01HU IYD Antibody, FITC conjugated
    Biotin CSB-PA754272LD01HU IYD Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine.
  • 基因功能參考文獻：
    1. The rate-limiting processes that contribute to the ability of flavin to promote reductive dehalogenation in human IYD. PMID: 26151430
    2. A switch between one- and two-electron chemistry of iodotyrosine deiodinase is controlled by substrate. PMID: 25395621
    3. Iodotyrosine deiodinase defect identified via genome-wide approach. PMID: 22535972
    4. high activity of human saliva peroxidase with iodide as a substrate may play a crucial role in the bioavailability and metabolism of biologically active iodide. PMID: 21870604
    5. Mutations in DEHAL1 leads to hypothyroidism, goiter and mental retardation (Review) PMID: 20298747
    6. molecular cloning and investigation of the localization and activity of DEHAL1 PMID: 15289438
    7. the cytoplasmic tail of DEHAL1 could play a role in the stability of the protein PMID: 16910871
    8. Diffuse cytoplasmatic localisation or downregulation of DEHAL1 expression in thyroid cancers suggests alteration or loss of DEHAL1 function during thyroid cell dedifferentiation. PMID: 17322488
    9. homozygous mutations in DEHAL1 appear to cause human iodotyrosine deiodinase deficiency, leading to hereditary hypothyroidism and goiter PMID: 18434651
    10. This study describes a functional mutation within IYD, demonstrating the molecular basis of the iodine wasting form of congenital hypothyroidism PMID: 18765512

    顯示更多

    收起更多

  • 相關疾病：
    Thyroid dyshormonogenesis 4 (TDH4)
  • 亞細胞定位：
    Cell membrane; Single-pass membrane protein. Cytoplasmic vesicle membrane.
  • 蛋白家族：
    Nitroreductase family
  • 組織特異性：
    Expressed at a high level in thyroid gland (at protein level). Expressed at a high level in thyroid gland and at lower level in kidney and trachea.
  • 數據庫鏈接：

    HGNC: 21071

    OMIM: 274800

    KEGG: hsa:389434

    STRING: 9606.ENSP00000229447

    UniGene: Hs.310225



主站蜘蛛池模板： 日本一卡二卡3卡四卡网站精品 | 亚洲va中文字幕无码久久| 人妻出轨av中文字幕| 午夜精品影视国产一区在线麻豆 | 天堂久久久久va久久久久| 日本丰满人妻xxxxxhd| 浴室人妻的情欲hd三级国产| 99热精品久久只有精品| 日本精品一区二区三区四区| av无码天堂一区二区三区| 色婷婷亚洲精品综合影院| 日本少妇春药特殊按摩3| 一本大道av伊人久久综合| 国产色播av在线观看| 影音先锋日日狠狠久久| 99久久精品费精品国产一区二| 风韵多水的老熟妇| 久久久久久久极品内射| 午夜福利片手机在线播放| 亚洲欧美在线制服丝袜国产| 久久久成人毛片无码| 欧美成人精品第一区二区三区| 欧美极品video粗暴| 欧美极品色午夜在线视频| 欧美牲交a欧美牲交aⅴ免费| www夜片内射视频日韩精品成人| 99久久精品国产成人综合| 国产成熟女人性满足视频| 亚洲国产精品成人午夜在线观看| 中文字幕日本人妻久久久免费| 国内揄拍国内精品对白| 99这里有精品视频视频| 国产精品99久久99久久久动漫| 国产情侣一区二区三区| 亚洲日韩看片无码电影| 一本色道久久88精品综合| 青青久在线视频免费观看| 天堂中文8资源在线8| 亚洲精品无码你懂的| 人成午夜免费视频无码| 成人伊人精品色xxxx视频|