在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. IPO11 Antibody

IPO11 Antibody

  • 中文名稱：
    IPO11兔多克隆抗體
  • 貨號(hào)：
    CSB-PA887057LA01HU
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) IPO11 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IPO11
  • 別名：
    Imp11 antibody; Importin 11 antibody; Importin-11 antibody; IPO11 antibody; IPO11_HUMAN antibody; Ran binding protein 11 antibody; Ran-binding protein 11 antibody; RanBP11 antibody; SLRN antibody; Synleurin antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Importin-11 protein (1-270AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，IPO11 Antibody (CSB-PA887057LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于IPO11 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA887057LB01HU IPO11 Antibody, HRP conjugated ELISA
    FITC CSB-PA887057LC01HU IPO11 Antibody, FITC conjugated
    Biotin CSB-PA887057LD01HU IPO11 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of UBE2E3, and of RPL12.
  • 基因功能參考文獻(xiàn)：
    1. High IPO11 expression is associated with migration, invasion, and progression of bladder cancer. PMID: 29602637
    2. IPO11 copy number amplification and importin-11 overexpression are promising biomarkers for predicting the progression and poor prognosis of patients with NMIBC. PMID: 27689332
    3. IPO11 provides protection in another way, the researchers found. The transport receptor also shuttles UBE2E1, an enzyme necessary for PTEN ubiquitination, into the nucleus. Thanks to IPO11, normal cells keep all of their UBE2E1 in the nucleus, allowing PTEN to continue functioning in the cytoplasm. In cells lacking IPO11, UBE2E1 remains in the cytoplasm and promotes the destruction of PTEN. PMID: 28258103
    4. IPO11-HTR1A is a significant risk gene region for attention deficit hyperactivity disorder in Caucasians. PMID: 26079129
    5. Data indicate that ubiquitin-conjugating enzyme UBE2E3 and importin 11 (Imp-11)promote the nuclear accumulation and activity of transcription factor NF-E2 (Nrf2) by restricting the transcription factor from partitioning to the mitochondria PMID: 25378586

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Importin beta family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20628

    OMIM: 610889

    KEGG: hsa:51194

    STRING: 9606.ENSP00000386992

    UniGene: Hs.482269



主站蜘蛛池模板： 精品香蕉一区二区三区| 亚洲日韩va在线视频| 国产成人午夜福利免费无码r| 国产精品无码久久综合| 四川少妇大战4黑人| 亚洲欧美日本国产专区一区| 亚洲精品成人久久电影网| 四虎www成人影院观看| 亚洲色婷婷久久精品av蜜桃久久 | 在线 | 一区二区三区| 无码人妻精品丰满熟妇区| 久久99精品久久久久久蜜芽| 法国伦理少妇愉情| 国产精品久久久一区二区| 国产激情久久久久久熟女老人 | 中文亚洲欧美日韩无线码| 国产精品国产三级国产普通话| 久久午夜私人影院| 怡红院成永久免费人视频新的| 国产成人精品亚洲日本在线| 男女啪啪做爰高潮无遮挡| 久久国产精品国产四虎90后| 好硬好湿好爽再深一点动态图视频| 国产精品无码制服丝袜| 国产未发育呦交视频| 国产免费福利在线视频| 最新日韩精品中文字幕| 日韩精品人妻系列无码专区免费 | 粗大挺进尤物人妻中文字幕| 国产欧美另类精品久久久| 国产大学生粉嫩无套流白浆| 一个人看的www免费视频在线观看| 亚洲ⅴ国产v天堂a无码二区| 午夜无码一区二区三区在线| 无码人妻丰满熟妇a片护士| 成 人 色 网 站免费观看| 人妻三级日本香港三级极| 国产精品自在在线午夜免费| 日韩精品久久无码中文字幕| 又色又爽又高潮免费观看 | 五月花成人网|