在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. INPP5B Antibody

INPP5B Antibody

  • 中文名稱：
    INPP5B兔多克隆抗體
  • 貨號：
    CSB-PA011734LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA011734LA01HU diluted at 1:400 and staining in paraffin-embedded human glioma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA011734LA01HU diluted at 1:400 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of Hela cells with CSB-PA011734LA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) INPP5B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    4 antibody; 5-trisphosphate 5-phosphatase antibody; 5PTase antibody; 75 kDa inositol polyphosphate 5 phosphatase antibody; 75 kDa inositol polyphosphate-5-phosphatase antibody; 75kDa antibody; EC 3.1.3.36 antibody; I5P2_HUMAN antibody; Inositol polyphosphate 5-phosphatase II antibody; Inositol polyphosphate-5-phosphatase B antibody; Inositol polyphosphate-5-phosphatase; 75kDa antibody; INPP5B antibody; Inpp5b protein antibody; INPP5P antibody; MGC65156 antibody; MGC71303 antibody; OTTHUMP00000004726 antibody; OTTHUMP00000004727 antibody; OTTHUMP00000004728 antibody; Phosphoinositide 5 phosphatase antibody; Phosphoinositide 5-phosphatase antibody; Type II inositol 1,4,5 trisphosphate 5 phosphatase antibody; Type II inositol-1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Type II inositol 1,4,5-trisphosphate 5-phosphatase protein (78-178AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，INPP5B Antibody (CSB-PA011734LA01HU)，的標記方式是Non-conjugated。對于INPP5B Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA011734LB01HU INPP5B Antibody, HRP conjugated ELISA
    FITC CSB-PA011734LC01HU INPP5B Antibody, FITC conjugated
    Biotin CSB-PA011734LD01HU INPP5B Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Hydrolyzes phosphatidylinositol 4,5-bisphosphate (PtIns(4,5)P2) and the signaling molecule phosphatidylinositol 1,4,5-trisphosphate (PtIns(1,4,5)P3), and thereby modulates cellular signaling events.
  • 基因功能參考文獻：
    1. OCRL-mutated fibroblasts from patients with Dent-2 disease exhibit INPP5B-independent phenotypic variability relatively to Lowe syndrome cells PMID: 25305077
    2. The crystal structures of human INPP5B in complex with phosphoinositide substrate analogs revealed a membrane interaction patch likely to assist in sequestering substrates from the lipid bilayer. PMID: 24704254
    3. study found mouse Inpp5b and human INPP5B differ in their transcription, splicing and amino acid sequence; observations form foundation for analyzing the functional basis for the difference in how Inpp5b and INPP5B compensate for loss of Ocrl function PMID: 20872266
    4. The homologous phosphatase Inpp5b was unable to complement the Ocrl1-dependent cell migration defect. PMID: 19700499
    5. INPP5B is also localised to the early secretory pathway including the Golgi apparatus and ER-to-Golgi intermediate compartment (ERGIC). PMID: 17956944
    6. The NH2-terminal region of OCRL, but not of INPP5B, binds clathrin heavy chain. PMID: 19536138

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytosol. Endoplasmic reticulum-Golgi intermediate compartment. Early endosome membrane. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, phagosome membrane. Golgi apparatus.
  • 蛋白家族：
    Inositol 1,4,5-trisphosphate 5-phosphatase type II family
  • 組織特異性：
    Platelets.
  • 數據庫鏈接：

    HGNC: 6077

    OMIM: 147264

    KEGG: hsa:3633

    STRING: 9606.ENSP00000362115

    UniGene: Hs.449942



主站蜘蛛池模板： 亚洲精品午夜无码电影网| 香蕉在线 亚洲 欧美 专区| 久久久久四虎精品免费入口| 成·人免费午夜无码视频蜜芽| 色夜码无码av网站| 国产无套精品一区二区| 亚洲夜夜性无码| 久久久久se色偷偷亚洲精品av| 边吃奶边添下面好爽| 久久国产成人免费网站777| 蜜桃av无码免费看永久| 大伊香蕉在线精品视频75| 国产做a爰片久久毛片a片美国| 国产免费观看久久黄av片| 成年无码av片| 国产精品多人p群无码| 亚洲色成人网站www永久蜜芽 | 国产又猛又黄又爽| 亚洲中文字幕码在线电影| 一本无码中文字幕在线观| 免费1级a做爰片在线观看| 亚洲性啪啪无码av天堂| 久久国产36精品色熟妇| 国产乱码日产精品bd| 2020年国产精品| 久久99亚洲精品久久频| 少妇的肉体aa片免费| 综合色区亚洲熟妇另类| 国产精品久久久久久免费软件| 久热爱精品视频线路一| 青青草原亚洲| 国产精品9999久久久久仙踪林| 日韩精品一卡2卡三卡4卡| 国产精品卡1卡2卡3网站| 久久天天躁狠狠躁夜夜2019| 337p日本欧洲亚洲大胆| 中文在线а√在线天堂中文| 少妇高潮无套内谢麻豆传| 亚洲人成人无码www影院| 精品无码国产av一区二区| 久久99精品久久久久久齐齐|