在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. ING3 Antibody, FITC conjugated

ING3 Antibody, FITC conjugated

  • 中文名稱：
    ING3兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA865171LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) ING3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ING3
  • 別名：
    ING3 antibody; HSPC301 antibody; Inhibitor of growth protein 3 antibody; p47ING3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Inhibitor of growth protein 3 protein (51-223AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome.
  • 基因功能參考文獻：
    1. results reveal the molecular mechanism of H3K4me3 selection by the ING3PHD and suggest that this interaction is important for mediating ING3 tumor suppressive activities. PMID: 27281824
    2. High ING3 expression is associated with prostate cancer. PMID: 26803516
    3. ING3 levels may serve as a surrogate for growth rate, and suggest possible roles for ING3 in growth and self renewal and related diseases such as cancer. PMID: 25819753
    4. Downregulated ING3 expression might play an important role in colorectal adenoma-adenocarcinoma sequence. PMID: 24927342
    5. that ING3 may be an important marker for human hepatocellular carcinoma progression and prognosis, as well as a potential therapeutic target. PMID: 22550337
    6. Data show that ING3 is degraded by the ubiquitin-proteasome pathway through the SCF(Skp2) complex. PMID: 19935701
    7. we have isolated a novel ING family gene, p47ING3, which modulates p53-mediated transcription, cell cycle control, and apoptosis. The p47ING3 gene is located at chromosome 7q31.3 and consists of 12 exons that encode 418 amino acids PMID: 12545155
    8. ING3 may be an important marker for human melanoma progression and prognosis as well as a potential therapeutic target. PMID: 17634537
    9. ING3 would function as a potential tumor suppressor molecule and that low levels of ING3 may indicate an aggressive nature of head and neck cancer. PMID: 18081876
    10. Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers. PMID: 12080476

    顯示更多

    收起更多

  • 相關疾病：
    Squamous cell carcinoma of the head and neck (HNSCC)
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    ING family
  • 組織特異性：
    Expressed in brain, heart, kidney, liver, lung, ovaries, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus.
  • 數據庫鏈接：

    HGNC: 14587

    OMIM: 275355

    KEGG: hsa:54556

    STRING: 9606.ENSP00000320566

    UniGene: Hs.489811



主站蜘蛛池模板： 欧美精品中文字幕在线视| 天天综合亚洲色在线精品| 国产精自产拍在线看中文| 亚洲精品久久久久中文字幕m男 | 亚洲色播爱爱爱爱爱爱爱| 四虎国产精品成人免费久久| 国产精品高潮呻吟av久久黄 | 少妇人妻邻居| 亚洲国产成人av人片久久| av激情亚洲男人的天堂| 国产亚洲综合欧美一区二区| 欧美内射rape视频| 亚洲中文字幕无码人在线| 一本大道东京热无码视频| 国产精品亚洲a∨天堂| 男男车车的车车网站w98免费| 寂寞少妇做spa按摩无码| 国产精品高潮呻吟av久久小说 | 少妇厨房愉情理伦bd在线观看| 中文字幕奈奈美被公侵犯| 国产亚洲欧洲aⅴ综合一区| 色吊丝av中文字幕| 久久久久蜜桃精品成人片| 天堂资源在线官网| 欧美成人片一区二区三区| 国产人与禽zoz0性伦| 国产精品亚洲玖玖玖在线观看| 双乳奶水饱满少妇呻吟| 少女韩国电视剧在线观看完整| 动漫人妻h无码中文字幕| 67pao国产成视频永久免费| 中文字幕av无码一区二区三区 | 国产片精品av在线观看夜色| 天天天狠天天碰天天爱| 久久妇女高潮喷水多| 国产人妻鲁鲁一区二区| 女被啪到深处喷水gif动态图| 精品香蕉99久久久久网站| 欧美乱妇狂野欧美在线视频| 在线看片免费人成视频在线影院 | 超薄丝袜足j好爽在线观看 |