在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

IMPACT Antibody, FITC conjugated

  • 中文名稱:
    IMPACT兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA889191LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) IMPACT Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    IMPACT
  • 別名:
    IMPACT antibody; Impact homolog (mouse) antibody; Impact homolog antibody; impact RWD domain protein antibody; IMPCT_HUMAN antibody; Imprinted and ancient gene protein homolog antibody; MGC33718 antibody; Protein IMPACT antibody; RWD domain containing 5 antibody; RWDD5 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein IMPACT protein (41-320AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its inhibitory action on EIF2AK4/GCN2, plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
  • 基因功能參考文獻:
    1. Data suggest that high expression of protein IMPACT homolog in non-immune cells acts as a protective mechanism against indoleamine 2,3-dioxygenase (IDO)-induced GCN2 activation, making them resistant to the amino acid-deprived environment caused by IDO. PMID: 20648630
    2. It thus seems that lineage-specific enhancement of gene expression rather than the tandem repeat per se played a critical role in the evolution of imprinting of Impact. PMID: 15752730
    3. segmental duplication followed by enhancement of the promoter activity is responsible for the species-specific imprinting of Impact PMID: 15871461
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    IMPACT family
  • 組織特異性:
    Widely expressed. Expressed at high level in brain.
  • 數據庫鏈接:

    HGNC: 20387

    OMIM: 615319

    KEGG: hsa:55364

    STRING: 9606.ENSP00000284202

    UniGene: Hs.515317



主站蜘蛛池模板: 国产精品a成v人在线播放| 真人无码作爱免费视频| 好爽别插了无码视频| 国产成人麻豆精品午夜福利在线| 久久久精品2019免费观看| 国产精品人妻熟女男人的天堂 | 免费人成视频在线观看网站| 日本伊人色综合网| 98久久人妻少妇激情啪啪| 久久天天躁狠狠躁夜夜2020老熟妇| 少妇伦子伦精品无吗| 俺也来俺也去俺也射| 欧美村妇激情内射| 特级a欧美做爰片第一次| 国产成人av综合色| 久久久久女人精品毛片| 精品服丝袜无码视频一区| 亚洲欧洲日韩综合久久| 国产日韩一区二区三免费高清| 五十路熟妇亲子交尾| 丰满人妻被黑人中出849| 亚洲第一页综合图片自拍| 乱码av麻豆丝袜熟女系列| 国产ae86亚洲福利入口| 公与淑婷厨房猛烈进出视频免费| 国产无套中出学生姝| 后入内射欧美99二区视频| 成 人 网 站94免费观看| 日本熟人妻中文字幕在线| 无码欧精品亚洲日韩一区| 国产精品国产av片国产| 国产成人精品自在线拍| 国产精品人妻一区二区三区四 | 日本丰满少妇裸体自慰| 国产精品美女乱子伦高| 任我爽橹在线精品视频| 一区二区三区在线 | 欧洲| 中文字幕v亚洲ⅴv天堂| 欧美性猛交xxxxx按摩欧美| 老熟女高潮喷水了| 色婷婷久久久swag精品|