在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. IMPACT Antibody, Biotin conjugated

IMPACT Antibody, Biotin conjugated

  • 中文名稱：
    IMPACT兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA889191LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) IMPACT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IMPACT
  • 別名：
    IMPACT antibody; Impact homolog (mouse) antibody; Impact homolog antibody; impact RWD domain protein antibody; IMPCT_HUMAN antibody; Imprinted and ancient gene protein homolog antibody; MGC33718 antibody; Protein IMPACT antibody; RWD domain containing 5 antibody; RWDD5 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein IMPACT protein (41-320AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its inhibitory action on EIF2AK4/GCN2, plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
  • 基因功能參考文獻：
    1. Data suggest that high expression of protein IMPACT homolog in non-immune cells acts as a protective mechanism against indoleamine 2,3-dioxygenase (IDO)-induced GCN2 activation, making them resistant to the amino acid-deprived environment caused by IDO. PMID: 20648630
    2. It thus seems that lineage-specific enhancement of gene expression rather than the tandem repeat per se played a critical role in the evolution of imprinting of Impact. PMID: 15752730
    3. segmental duplication followed by enhancement of the promoter activity is responsible for the species-specific imprinting of Impact PMID: 15871461
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    IMPACT family
  • 組織特異性：
    Widely expressed. Expressed at high level in brain.
  • 數據庫鏈接：

    HGNC: 20387

    OMIM: 615319

    KEGG: hsa:55364

    STRING: 9606.ENSP00000284202

    UniGene: Hs.515317



主站蜘蛛池模板： 欧美人禽杂交狂配免费看| 中文字幕人成无码人妻| 无码人妻丰满熟妇精品区| 少妇性l交大片毛多| 国产aⅴ精品一区二区三区久久| 亚洲精品无码永久中文字幕| 884aa四虎影成人精品| 国产精品美女一区二区三区| 成人亚洲精品久久久久软件| 人妻少妇被粗大爽.9797pw| 亚洲最新无码成av人| 深夜国产成人福利在线观看| 成人丝袜激情一区二区| 中文字幕丰满乱孑伦无码专区| 色情无码一区二区三区| 女人被狂c到高潮视频网站| 青青草无码精品伊人久久| 一本久久精品一区二区| 国产乱子伦一区二区三区| 日本丰满妇人成熟免费中文字幕| 天天爽亚洲中文字幕| 国产大量精品视频网站| 色综合久久一区二区三区| 熟女内射v888av| 久久伊人精品波多野结衣| 免费国产成人高清在线观看网站| 欧洲美女黑人粗性暴交| 久久久久久久人妻无码中文字幕爆| 国产永久免费观看视频| av天堂中av世界中文在线播放| 久久国产福利国产秒拍飘飘网| 色一情一乱一伦| 少妇高清精品毛片在线视频| 果冻传媒一区二区天美传媒| 国产av午夜精品一区二区三区| 黑人巨茎美女高潮视频 | 欧美极品少妇×xxxbbb| 国产精品成人久久电影| 亚洲日产韩国一二三四区| 亚洲人成网站在小说| 久久国产精品福利一区二区三区|