在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. IMPACT Antibody, Biotin conjugated

IMPACT Antibody, Biotin conjugated

  • 中文名稱：
    IMPACT兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA889191LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) IMPACT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    IMPACT
  • 別名：
    IMPACT antibody; Impact homolog (mouse) antibody; Impact homolog antibody; impact RWD domain protein antibody; IMPCT_HUMAN antibody; Imprinted and ancient gene protein homolog antibody; MGC33718 antibody; Protein IMPACT antibody; RWD domain containing 5 antibody; RWDD5 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Protein IMPACT protein (41-320AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation. Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its inhibitory action on EIF2AK4/GCN2, plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
  • 基因功能參考文獻：
    1. Data suggest that high expression of protein IMPACT homolog in non-immune cells acts as a protective mechanism against indoleamine 2,3-dioxygenase (IDO)-induced GCN2 activation, making them resistant to the amino acid-deprived environment caused by IDO. PMID: 20648630
    2. It thus seems that lineage-specific enhancement of gene expression rather than the tandem repeat per se played a critical role in the evolution of imprinting of Impact. PMID: 15752730
    3. segmental duplication followed by enhancement of the promoter activity is responsible for the species-specific imprinting of Impact PMID: 15871461
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    IMPACT family
  • 組織特異性：
    Widely expressed. Expressed at high level in brain.
  • 數據庫鏈接：

    HGNC: 20387

    OMIM: 615319

    KEGG: hsa:55364

    STRING: 9606.ENSP00000284202

    UniGene: Hs.515317



主站蜘蛛池模板： 国产乱理伦片在线观看| 中文国产成人精品久久久| 人妻三级日本三级日本三级极 | 国产欧美精品区一区二区三区| 一出一进一爽一粗一大视频| 国产精品狼人久久久久影院| 亚洲亚洲人成综合丝袜图片| 日本高清成本人视频一区| 国产手机在线αⅴ片无码观看| 亚洲欧美国产成人综合欲网| 国产人妻xxxx精品hd| 国产欧美成人一区二区a片| 狠狠综合久久av一区二区| 国产成+人+综合+亚洲欧美丁香花| 亚洲精品成人福利网站| 欧美色欧美亚洲高清在线视频| 玩弄少妇人妻| 亚洲欧美日韩中文播放| 亚洲精品av网站在线观看| 国产成人av一区二区三区不卡| 国产麻豆放荡av剧情演绎| 亚洲一区日韩高清中文字幕亚洲| 亚洲1卡二卡三新区2022| 国产精品 视频一区 二区三区| 亚洲国产精品综合久久网各| 风韵犹存丰满大屁股熟妇视频| 中文字幕无码家庭乱欲| 亚洲精品第一国产综合野草社区 | 亚洲精品国产成人一区二区| 丁香婷婷六月综合交清| 国产偷窥熟妇高潮呻吟| 人妻少妇heyzo无码专区 | 成人国产mv免费视频| 国产精品无码一区二区牛牛| 人人超碰人人爱超碰国产| 成人做爰免费视频免费看| 性男女做视频观看网站| 国产精品久久| 国产激情视频一区二区三区| 成人片黄网站a毛片免费观看| 国产精品白丝av网站在线观看|